In higher education, blended learning technology combining e-learning and classroom activities has become widespread. Blended learning contributes to the introduction of variable forms and ways of interaction between students and teachers, interaction of study process participants with content, and the expansion of the teacher’s toolkit when working with students. In order to identify and justify the pedagogical conditions of effective organization of blended learning in universities, the authors have described the essence and main components of blended learning technology, and the options of its implementation using learning management systems (LMS). LMS can be classified as to types of licensing, a set of functionality, the module-based criterion, the “customer requirement” criterion, and physical location. The articled presents and identifies features and capabilities of one of the most common learning management systems - LMS MOODLE. The authors reveal pedagogical conditions for the successful implementation of blended learning technology at a university: development of a syllabus and training curricula, correlation of the possibilities of their implementation with the use of blended learning technology; competent course design and implementation, as well as active updating of the content of LMS courses to ensure their quality and relevance; providing timely teacher support for communication and feedback with students; development and application of special methods for monitoring and assessing educational results to carry out reliable and valid diagnostics of learning outcomes and provide prompt feedback; development of high-quality methodological support for teachers on the organization and implementation of the educational process in new conditions and produce methodological materials for students; ensuring a high degree of readiness of students and teachers to implement training in a new format, organize their training and support end contribute to the development of digital competences.