In this paper, a novel silicon-controlled rectifier (SCR) electrostatic discharge (ESD) protection device, called low voltage triggered SCR (LVTSCR) triggered SCR (LVTSCRTSCR), is proposed for 3.3 V I/O protection applications in 0.18 μm CMOS technology. One side of the device is the traditional LVTSCR structure, and other side is the traditional SCR structure. The two structures are connected by a floating P+ diffusion layer. The working principle of LVTSCRTSCR was verified by the TCAD simulation results and TLP test results. The test results show that the triggering voltage of LVTSCRTSCR is determined by the traditional LVTSCR, with a value of 9.850 V. The holding voltage of the device can be effectively improved by increasing the size of the floating diffusion layer D4. When D4 = 6 μm, the holding voltage can be 4.491 V, suitable for 3.3 V I/O.