Introduction: Fluid cytology studies are preferred over biopsy, which may miss focal lesions. Objectives: To examine the cytology of aspirated pleural and ascitic uid and classify them according to age, sex, macroscopic appearance, and neoplastic or non-neoplastic type. Material and Methods: Total 441 uids were studied, of which 198 were pleural uid and 243 were ascitic uid. The received uid was centrifuged and smears were prepared from the sediment and stained with giemsa stain. Maximum c Results: ases were observed in 21-30 years in pleural uid and 51-60 years in ascitic uid. Overall male : female ratio was 1.05:1. Ascites and pleural uid show the most common non- malignant lesion is inammatory pathology and the most common malignant lesion is adenocarcinoma. This non-invasive Conclusion: technique has become an essential tool in the diagnosis of many diseases and is especially valuable in cases where more invasive procedures may be contraindicated. Cytology should be considered the rst line of investigation as it is a simple and cost effective procedure.