Integration Of Elements Research Articles

Sino-US film collaboration in practice: Mulan

ABSTRACT This article examines recent Sino-US film collaborations, focusing on Mulan (2020) against the backdrop of geopolitical shifts and the COVID-19 pandemic. Through in-depth interviews and a case study, it investigates the lukewarm reception of Mulan (2020) in China. The study explores how external pressures have disrupted the previously thriving partnership, leading to investment uncertainty, intensified censorship, and shifts in audience consumption towards online platforms, which have exacerbated piracy issues. It also addresses the political tensions surrounding Mulan (2020), including controversies related to Xinjiang and Hong Kong, which hindered its box-office success in Mainland China despite domestic support. A comparative analysis with Mulan (1998) assesses the evolution of feminist themes and filial piety in the 2020 adaptation. The findings indicate that while efforts were made to enhance feminist narratives and cultural motifs, the execution was superficial, treating complex cultural themes as mere embellishments rather than integral elements of the narrative. The film’s portrayal of these themes within a predominantly Western framework highlights ongoing challenges in bridging cultural narratives in Sino-US film productions. The findings underscore the profound impact of geopolitics and reveal the contentious portrayal of feminism and cultural integration in Mulan (2020), emphasizing the challenges in Sino-US film collaborations.

What is Antarctica?

ABSTRACT Antarctica is an integral element to the study of global systems and global governance – for good reason. It offers an interesting case study of how nation-states have assembled a shared understanding of how to govern a continent and surrounding ocean that has never had an indigenous human population. The Antarctic Treaty (1959) lies at the heart of this consensus-based model of regional governance. There are rules, norms and values that underpin the resultant governance. Remarkably, nation-states accepted that territorial claims would be deferred for the duration of the Treaty and worked purposefully to find areas of agreement. Yet, Antarctica remains a contested space. It is geopolitically contested with fears that great power competition might disrupt further that consensual-based model. Beyond that, Antarctica has been capable of entertaining both complementary and rival geographical imaginaries, from being thought of as a scientific laboratory to a planetary common. Most recently, there has been a concerted attempt to think of Antarctica as an object invested with legal personality. Looking ahead, the world’s oceans, polar regions and even outer space are going to face growing scrutiny and challenge as resource worries, climate change and strategic competition makes themselves felt.

Unraveling the adaptive strategies of Mycoplasma hominis through proteogenomic profiling of clinical isolates.

Mycoplasma hominis (M. hominis) belongs to the class Mollicutes, characterized by a very small genome size, reduction of metabolic pathways, including transcription factors, and the absence of a cell wall. Despite this, they adapt well not only to specific niches within the host organism but can also spread throughout the body, colonizing various organs and tissues. The adaptation mechanisms of M. hominis, as well as their regulatory pathways, are poorly understood. It is known that, when adapting to adverse conditions, Mycoplasmas can undergo phenotypic switches that may persist for several generations. To investigate the adaptive properties of M. hominis related to survival in the host, we conducted a comparative phenotypic and proteogenomic analysis of eight clinical isolates of M. hominis obtained from patients with urogenital infections and the laboratory strain H-34. We have shown that clinical isolates differ in phenotypic features from the laboratory strain, form biofilms more effectively and show resistance to ofloxacin. The comparative proteogenomic analysis revealed that, unlike the laboratory strain, the clinical isolates possess several features related to stress survival: they switch carbon metabolism, activating the energetically least advantageous pathway of nucleoside utilization, which allows slowing down cellular processes and transitioning to a starvation state; they reconfigure the repertoire of membrane proteins; they have integrative conjugative elements in their genomes, which are key mediators of horizontal gene transfer. The upregulation of the methylating subunit of the restriction-modification (RM) system type I and the additional components of RM systems found in clinical isolates suggest that DNA methylation may play a role in regulating the adaptation mechanisms of M. hominis in the host organism. It has been shown that based on the proteogenomic profile, namely the genome sequence, protein content, composition of the RM systems and additional subunits HsdM, HsdS and HsdR, composition and number of transposable elements, as well as the sequence of the main variable antigen Vaa, we can divide clinical isolates into two phenotypes: typical colonies (TC), which have a high growth rate, and atypical (aTC) mini-colonies, which have a slow growth rate and exhibit properties similar to persisters. We believe that the key mechanism of adaptation of M. hominis in the host is phenotypic restructuring, leading to a slowing down cellular processes and the formation of small atypical colonies. This is due to a switch in carbon metabolism and activation the pathway of nucleoside utilization. We hypothesize that DNA methylation may play a role in regulating this switch.

Genetic Characteristics of Novel IncpSE5381-aadB Plasmids, Integrative and Mobilizable Elements, and Integrative and Conjugative Elements in Pseudomonas aeruginosa.

Pseudomonas aeruginosa is a common causative bacteria in nosocomial infections. This study aims to describe the structure and evolutionary characteristics of mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) from P. aeruginosa and to conduct bioinformatics and comparative genomic analysis to provide a deeper understanding of the genetic characteristics and diversity of MGEs in P. aeruginosa. Fifteen clinical isolates of P. aeruginosa from China were collected and sequenced in this study, and 15 novel MGEs were identified. Together with four MGEs from GenBank, a total of 19 MGEs were used to perform detailed modular structure dissection and sequence comparison. Then, the biological experiments were carried out to verify the biological characteristics of these isolates and MEGs. The novel MGEs identified in this study displayed diversification in modular structures, which showed complex mosaic natures. The seven types of 19 MGEs included in this study were divided into three groups: i) novel MGEs (firstly identified in this study): four IncpSE5381-aadB plasmids and three Tn7495-related integrative and mobilizable elements (IMEs); ii) newly defined MGEs (firstly designated in this study, but with previously determined sequences): four Tn7665-related IMEs; iii) novel transposons with reference prototypes identified in this study: two Tn6417-related integrative and conjugative elements (ICEs), two IS-based transposition units, two Tn501-related unit transposons, two Tn1403-related unit transposons. At least 36 ARGs involved in resistance to 11 different classes of antimicrobials and heavy metals were identified. Additionally, three novel blaOXA variants were identified. Antimicrobial susceptibility testing showed that these variants were resistant to some β-lactamase antibiotics and blaOXA-1204 was additionally resistant to cephalosporins. The continuous evolution of ARG-carrying MGEs during transmission, leading to the emergence of novel MGEs or ARGs, which facilitates the spread of antibiotic resistance in P. aeruginosa and enhances the diversity of transmission modes of bacterial resistance.

Relativistic Electron Precipitation Events Driven by Solar Wind Impact on the Earth's Magnetosphere

AbstractCertain forms of solar wind transients contain significant enhancements of dynamic pressure and may effectively drive magnetosphere dynamics, including substorms and storms. An integral element of such driving is the generation of a wide range of electromagnetic waves within the inner magnetosphere, either by compressionally heated plasma or by substorm plasma sheet injections. Consequently, solar wind transient impacts are traditionally associated with energetic electron scattering and losses into the atmosphere by electromagnetic waves. In this study, we show the first direct measurements of two such transient‐driven precipitation events as measured by the low‐altitude Electron Losses and Fields Investigation CubeSats. The first event demonstrates storm‐time generated electromagnetic ion cyclotron waves efficiently precipitating sub‐relativistic and relativistic electrons from >300 keV to 2 MeV at the duskside. The second event demonstrates whistler‐mode waves leading to scattering of electrons from 50 to 700 keV on the dawnside. These observations confirm the importance of solar wind transients in driving energetic electron losses and subsequent dynamics in the ionosphere.

Isolation, Identification, Genomic Diversity, and Antimicrobial Resistance Analysis of Streptococcus suis in Hubei Province of China from 2021 to 2023.

Streptococcus suis (S. suis) is a zoonotic pathogen capable of causing severe diseases in humans and pigs, including meningitis, sepsis, polyserositis, arthritis, and endocarditis. This study aimed to investigate the biological characteristics of 19 strains of S. suis isolated from diseased pigs in Hubei Province between 2021 and 2023. Through bioinformatics analysis, we investigated the serotype, MLST, pan-genome characteristics, SNP, AMR, and ICE of the 19 S. suis isolates. Among the 19 S. suis strains, ten serotypes were identified, and serotype 9 was the most prevalent (21.05%). Ten new alleles and nine new sequence types (STs) were discovered, with ST28 and ST243 emerging as the predominant STs. The results of the pan-genomic analysis of S. suis indicate that there are 943 core genes, 2259 shell genes, and 5663 cloud genes. Through SNP evolutionary analysis, we identified a strong genetic similarity between SS31 and the reference genome P1/7. The analysis of antibiotic resistance genes revealed widespread presence of erm(B) and tet(O) genes among 19 strains of S. suis. This association may be linked to the high resistance of S. suis to lincosamides, macrolides, and tetracyclines. Integrative and conjugative elements (ICEs) and integrative and mobilizable elements (IMEs) were identified in 16 strains, with a carriage rate of 84.21%, and resistance genes were identified within the ICE/IME elements of 8 strains. Antimicrobial susceptibility testing revealed that all strains showed sensitivity to vancomycin and lincomycin but resistance to tilmicosin, tiamulin, amoxicillin, and doxycycline. This study contributes to our understanding of the genomic diversity of S. suis in Hubei Province of China, providing essential data for the comprehensive prevention and control of S. suis infections in China.

PLANNING FOR SUSTAINABLE DEVELOPMENT THROUGH THE INTEGRATION OF A NEW POLITICAL CULTURE

The article represents an attempt to investigate the phenomenon of political culture through the lens of sustainable development. Based on comparative approach and Political Science provisions, implementation of UN Sustainable Development Goals is considered within the integration of a new political culture. Patterns characteristic for the USA and China are employed as examples, and the broad use of ‘sustainable value’ notion is suggested. It is shown that sustainability value and political culture are integral elements of sustainable development planning and practice, which should give the synergy effect.

Application of binary lessons in mathematics as a factor of achieving the requirements of the updated Federal State Standards of basic general education

As part of the introduction of the updated Federal State Educational Standard for basic general education, the school is required to pay special attention not only to meeting the requirements for subject learning outcomes, but also to the development of functional literacy and soft skills. As part of the implementation of this direction, special attention is paid to increasing the level of mathematical literacy of students as an integral element of functional literacy. The key subjects in secondary schools that contribute to this process are mathematics, physics and computer science. Since the potential of meta-subjectivity and interdisciplinary communication of the subject of mathematics directly depends on its potential as a teaching and educational system, the article makes a critical assessment of the content of training and introduces proposals for its optimization in terms of focus on both the formation of mathematical literacy and the development of the mind and thinking of students, the formation of their mathematical culture and metamathematical knowledge. Paying attention to the mathematical component, the article notes that currently, as part of the implementation of the basic general education program, the emphasis is shifting to the area of the possibility of applying mathematical knowledge, skills and abilities to the problems of everyday reality. Thus, to increase the level of mathematical literacy as an integral element of functional literacy, an interdisciplinary consideration of the mathematics course and a search for ways to implement interdisciplinary connections are required. From this point of view, as an example for such an implementation, the issue of compiling and solving educational problems that can be used when conducting binary or integrated lessons in mathematics and physics was considered. The integrative nature of the content of binary lessons in mathematics and physics means the need for a synthesis of knowledge and methods of activity for students to implement it, which allows students to better assimilate the material, since they can see the connection between different subjects

Relatedness and product complexity meet gravity models of international trade

Researchers have long used gravity models to analyze international trade patterns, identify export opportunities, and negotiate trade agreements. Recent research has emphasized the significance of relatedness and product complexity research in developing robust economic development strategies. This paper presents a novel approach, incorporating relatedness and product complexity as integral elements for interpreting export potential within gravity models powered by machine learning. Our approach stands out for its proficiency in accurately predicting bilateral trade values at a detailed product group level, providing valuable insights for policymakers and other stakeholders. The research leverages random forest machine learning models for predictions and incorporates relatedness and complexity to reveal new dimensions in international trade analysis.

BIOETHICS AND PATIENT INVOLVEMENT IN MEDICAL DECISION-MAKING: CHALLENGES AND ETHICAL IMPLICATIONS IN CLINICAL PRACTICE

Background Patient involvement in medical decision-making has become an integral element in contemporary healthcare, affirming the rights and autonomy of patients in their care processes. This review presents an in-depth study concerning the issue of patient involvement in medical decision-making from a bioethical perspective, as well as exploring the challenges and ethical implications that arise in clinical practice. Methods A literature review method is used in this study, encompassing various literary sources that detail bioethical principles such as patient autonomy, justice, beneficence, and non-maleficence in the context of medical decision-making. Additionally, this study seeks a profound understanding of how clinical practices and health policies influence patient involvement and present specific ethical challenges. Result The findings of this literature review highlight the crucial role of bioethics in shaping more ethical practices in medical decision-making and identify key issues that need attention, such as inequality in access and information, value conflicts between patients and healthcare providers, and the need to focus on the best interests of the patient. Conclusion By understanding these ethical challenges and implications, we can better develop guidelines and policies that support meaningful and ethical patient involvement in clinical practice. Thus, this research contributes to the development of healthcare that respects bioethical values as well as the rights and needs of patients.

Integrative and Conjugative Elements and Prophage DNA as Carriers of Resistance Genes in Erysipelothrix rhusiopathiae Strains from Domestic Geese in Poland.

Goose erysipelas is a serious problem in waterfowl breeding in Poland. However, knowledge of the characteristics of Erysipelothrix rhusiopathiae strains causing this disease is limited. In this study, the antimicrobial susceptibility and serotypes of four E. rhusiopathiae strains from domestic geese were determined, and their whole-genome sequences (WGSs) were analyzed to detect resistance genes, integrative and conjugative elements (ICEs), and prophage DNA. Sequence type and the presence of resistance genes and transposons were compared with 363 publicly available E. rhusiopathiae strains, as well as 13 strains of other Erysipelothrix species. Four strains tested represented serotypes 2 and 5 and the MLST groups ST 4, 32, 242, and 243. Their assembled circular genomes ranged from 1.8 to 1.9 kb with a GC content of 36-37%; a small plasmid was detected in strain 1023. Strains 1023 and 267 were multidrug-resistant. The resistance genes detected in the genome of strain 1023 were erm47, tetM, and lsaE-lnuB-ant(6)-Ia-spw cluster, while strain 267 contained the tetM and ermB genes. Mutations in the gyrA gene were detected in both strains. The tetM gene was embedded in a Tn916-like transposon, which in strain 1023, together with the other resistance genes, was located on a large integrative and conjugative-like element of 130 kb designated as ICEEr1023. A minor integrative element of 74 kb was identified in strain 1012 (ICEEr1012). This work contributes to knowledge about the characteristics of E. rhusiopathiae bacteria and, for the first time, reveals the occurrence of erm47 and ermB resistance genes in strains of this species. Phage infection appears to be responsible for the introduction of the ermB gene into the genome of strain 267, while ICEs most likely play a key role in the spread of the other resistance genes identified in E. rhusiopathiae.

Finite element and experimental analysis of surface integrity and surface roughness of precision machining SiCp/Al

The silicon carbide particle-reinforced matrix composites, or SiCp/Al, have excellent mechanical qualities, but producing them is quite difficult since the SiC particles’ and the Al matrix’s properties differ greatly from one another. During the cutting process, the Ra local oscillation phenomena takes place; that is, surface roughness seems to grow, decrease, and then increase as the cutting depth increases within a particular cutting depth range while maintaining the same cutting speed and feed. To find out why this behavior occurred, a cutting experiment and a simulation analysis of SiCp/Al composites were performed. Tests were conducted to find out how varied cutting depths affected surface roughness, and a finite element model for two-dimensional cutting was created. Based on the data, it can be concluded that Ra’s local oscillation phenomena is responsible for the surface quality at various cutting speeds. At 100 mm/s, 200 mm/s, 300 mm/s, and 400 mm/s, respectively, the mutation’s surface quality improved by 29.6%, 14.3%, 19.6%, and 30.7% prior to the cutting depth. The analysis is justified by the fact that the depth of cut is increasing, the way in which particles are removed has changed and the percentage of scratches appears to be decreasing. As aluminium is a plastic material, plastic deformation occurs during cutting by the sub-cutting edge of the extrusion, coating the machined surfaces and producing fine cracks rather than plough furrows. In a sense, increasing the cutting thickness results in larger chips, more force on the particles in the cutting path and easier removal. At the same time, it reduces the width of the chip in future cuts, improving the surface quality of the process.

History and features of formation of the system of civic-patriotic education in Trans-Dniester in condition of an unrecognized state

Civic-patriotic consciousness and education is an integral element of any state claiming sovereignty and independence. With its help, the self-awareness of the population is formed, trust in the authorities and the state, and the legitimacy of power is ensured. The imperatives of the concept of civil-patriotic education in states with a “deficit” of international recognition, history of statehood, and financial resources actualize the mobilization nature of civil-patriotic ideology and its differentiation into the mother state and the patron state. This ideological position is relevant for Abkhazia, South Ossetia, Nagorno-Karabakh and Trans-Dniester, where the patron state (represented by Russia) is the support of the unrecognized state in ideological opposition to the mother state. In the article the history of formation and development of the system of civic-patriotic education in Trans-Dniester is viewed. It is closely connected with the history of the development of state, the construction of national security system and emerging threats to the statehood of the self-determined republic. The research was carried out using methods of historical, historical-political analysis, essential-substantive, chronological and system-structural methods. Analysis of civic-patriotic education in Trans-Dniester showed that it is a complex system of legal, institutional and functional elements that are closely included in the national security system of the Trans-Dniester Moldavian Republic.

Detection and genomic characterization of Klebsiella pneumoniae and Escherichia coli harboring tet(X4) in black kites (Milvus migrans) in Pakistan.

The emergence of plasmid-mediated tigecycline resistance gene tet(X4) among clinically relevant bacteria has promoted significant concerns, as tigecycline is considered a last-resort drug against serious infections caused by multidrug-resistant bacteria. We herein focused on the isolation and molecular characterization of tet(X4)-positive Klebsiella pneumoniae (K. pneumoniae) and Escherichia coli (E. coli) in wild bird populations with anthropogenic interaction in Faisalabad, Pakistan. A total of 150 birds including black kites (Milvus migrans) and house crows (Corvus splendens) were screened for the presence of tigecycline resistance K. pneumoniae and E. coli. We found two K. pneumoniae and one E. coli isolate carrying tet(X4) originating from black kites. A combination of short- and long-read sequencing strategies showed that tet(X4) was located on a broad host range IncFII plasmid family in K. pneumoniae isolates whereas on an IncFII-IncFIB hybrid plasmid in E. coli. We also found an integrative and conjugative element ICEKp2 in K. pneumoniae isolate KP8336. We demonstrate the first description of tet(X4) gene in the WHO critical-priority pathogen K. pneumoniae among wild birds. The convergence of tet(X4) and virulence associated ICEKp2 in a wild bird with known anthropogenic contact should be further investigated to evaluate the potential epidemiological implications. The potential risk of global transmission of tet(X4)-positive K. pneumoniaeand E. coli warrant comprehensive evaluation and emphasizes the need for effective mitigation strategies to reduce anthropogenic-driven dissemination of AMR in the environment.

Nano triumphs bulk in red light emission from Eu3+ doped Y2Zr2O7: Gel combustion versus solid state synthesis

Red phosphors are integral element of a phosphor converted white light emitting diodes (pc-WLEDs) which significantly impacts the color rendering index (CRI) and correlated color temperature (CCT) and thus provides a white light suitable for indoor applications. Red Light emitting Eu doped Y2Zr2O7 (YZOE) has been synthesized by two different synthesis methods viz. gel combustion (GC) and solid-state route (SS) wherein the former yielded nanocrystalline and latter leads to bulk YZOE. By virtue of lower light scattering, better electron-hole overlap integral and lower symmetric surrounding, nano YZOE displayed better photoluminescence properties in terms of emission intensity, photoluminescence quantum yield (PLQY) and excited state lifetime compared to its bulkier counterpart.

Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis.

Integrative and conjugative elements (ICEs) play a vital role in bacterial evolution by carrying essential genes that confer adaptive functions to the host. Despite their importance, the mechanism underlying the stable inheritance of ICEs, which is necessary for the acquisition of new traits in bacteria, remains poorly understood. Here, we identified SezAT, a type II toxin-antitoxin (TA) system, and AbiE, a type IV TA system encoded within the ICESsuHN105, coordinately promote ICE stabilization and mediate multidrug resistance in Streptococcus suis. Deletion of SezAT or AbiE did not affect the strain's antibiotic susceptibility, but their duple deletion increased susceptibility, mainly mediated by the antitoxins SezA and AbiEi. Further studies have revealed that SezA and AbiEi affect the genetic stability of ICESsuHN105 by moderating the excision and extrachromosomal copy number, consequently affecting the antibiotic resistance conferred by ICE. The DNA-binding proteins AbiEi and SezA, which bind palindromic sequences in the promoter, coordinately modulate ICE excision and extracellular copy number by binding to sequences in the origin-of-transfer (oriT) and the attL sites, respectively. Furthermore, AbiEi negatively regulates the transcription of SezAT by binding directly to its promoter, optimizing the coordinate network of SezAT and AbiE in maintaining ICESsuHN105 stability. Importantly, SezAT and AbiE are widespread and conserved in ICEs harbouring diverse drug-resistance genes, and their coordinated effects in promoting ICE stability and mediating drug resistance may be broadly applicable to other ICEs. Altogether, our study uncovers the TA system's role in maintaining the genetic stability of ICE and offers potential targets for overcoming the dissemination and evolution of drug resistance.

The right of military personnel to defense in the context of the European integration Ukraine

The relevance of the article is because certain aspects of harmonisation of legislation of Ukraine and the European Union member states, which are NATO members, in particular, in terms of ensuring the rights of military personnel to defence within criminal proceedings, require their own separate scientific understanding in the current context.
 The article analyses the provisions of the Convention for the Protection of Human Rights and Fundamental Freedoms of 1950, the Agreement between the Parties to the North Atlantic Treaty regarding the Status of their Forces of their Armed Forces, and national legislation of Ukraine.
 The author notes that today in Ukraine there is no separate system of military justice and no specialisation of attorneys at the level of law in cases of this category has been introduced. Given that our country is currently facing a full-scale invasion, and the establishment of a military justice system following the example of certain NATO member states requires significant budgetary expenditures, it seems appropriate to introduce mandatory specialisation of lawyers providing legal assistance to military personnel in criminal proceedings.
 At the same time, NATO member states do not have a same vision of the need to introduce a separate system of military justice, but the existence of agreed standards of legal protection of our military personnel and military personnel of these countries is one of the integral elements of Ukraine’s membership in the North Atlantic Alliance.
 In connection with the above, there is already an urgent need to study and implement the above standards in national legislation, including, inter alia, the consolidation of provisions in the legislation on the specialisation of lawyers providing legal aid in criminal proceedings of this category.

Recent development and fighting strategies for lincosamide antibiotic resistance.

SUMMARYLincosamides constitute an important class of antibiotics used against a wide range of pathogens, including methicillin-resistant Staphylococcus aureus. However, due to the misuse of lincosamide and co-selection pressure, the resistance to lincosamide has become a serious concern. It is urgently needed to carefully understand the phenomenon and mechanism of lincosamide resistance to effectively prevent and control lincosamide resistance. To date, six mobile lincosamide resistance classes, including lnu, cfr, erm, vga, lsa, and sal, have been identified. These lincosamide resistance genes are frequently found on mobile genetic elements (MGEs), such as plasmids, transposons, integrative and conjugative elements, genomic islands, and prophages. Additionally, MGEs harbor the genes that confer resistance not only to antimicrobial agents of other classes but also to metals and biocides. The ultimate purpose of discovering and summarizing bacterial resistance is to prevent, control, and combat resistance effectively. This review highlights four promising strategies, including chemical modification of antibiotics, the development of antimicrobial peptides, the initiation of bacterial self-destruct program, and antimicrobial stewardship, to fight against resistance and safeguard global health.

Organization of patient-oriented care for children diagnosed with cerebral palsy in outpatient settings

The desire to organize a patient-centered approach in interaction with patients is increasing, as focusing on the needs of the patient becomes an integral element of the quality of modern medical care. Target. To evaluate the provision of medical care to children with cerebral palsy using various methods that address the needs of not only the patient himself, but also his family members involved in his daily rehabilitation and social adaptation. Results. Indicators of the quality of patient-centered care include the actions of the patient and nursing staff, determining the content of care in a specific clinical situation, compliance with standards and algorithms of nursing activities, taking into account partnerships with patients and their relatives, and cooperation with other specialists of the multidisciplinary team. Conclusion. At the global level, the World Health Organization recognizes the patient-centered approach as key to modern assessment of the quality of health care. In this regard, the quality of patient-centered nursing activities, as a component of medical care, is determined by three main characteristics: structure, process and result.

Analisis Distribusi Dana Bantuan Perum Perumnas dalam Mendukung Tujuan Pembangunan Berkelanjutan (TPB)

Organizations and companies as integral elements in society are faced with the responsibility to understand and manage the impact of their operations on the environment, social and economy. The company program, especially BUMN, including Perum Perumnas, which supports the TPB, is the Social and Environmental Responsibility Program (TJSL). This research aims to analyze the role of Perum Perumnas in supporting the Sustainable Development Goals (TPB). This research method is data analysis research or company reports, especially the Perum Perumnas sustainability report for 2021-2022. The results of this research are that Perum Perumnas in 2021-2022 contributed to 10 of the 17 TPB. The order of cumulative TPB aid funds for 2021-2022, from largest to smallest, is TPB 16 (Peace, Justice and Resilient Institutions), TPB 8 (Decent Work and Economic Growth), TPB 6 (Clean Water and Decent Sanitation), SDG 11 (Sustainable Cities and Human Settlements), SDG 4 (Quality Education), SDG 2 (No Hunger), SDG 7 (Clean and Affordable Energy), SDG 14 (Protecting Marine Ecosystems), SDG 5 (Gender Equality), and TPB 10 (Reducing Inequality). The trend in the distribution pattern of Perum Perumnas TPB assistance areas in 2021-2022 follows the project locations handled by Perum Perumnas with the distribution of Perum Perumnas TPB assistance areas still focused on Java Island.