Formation Of High Level Research Articles

Subject position as a component of healthy personality education

The relevance of the research is due to the fact that over the past two centuries, the predominance of health-saving technologies in the education system has not been able to ensure the preservation and strengthening of children's health during the period of schooling. For the same reasons, the modern education system has not been able to solve this problem. As part of the implementation of these technologies, students were not considered as subjects of preserving and strengthening their health. The way out of this situation is in a comprehensive approach to solving this problem based on the education of a healthy personality, with the focus on the formation of students' subjective position in relation to the preservation and strengthening of their health. This process should involve various social institutions and the student himself, and create health-forming conditions in educational organizations and in society. The purpose of the study was to identify the level of formation of the subjective position of students in relation to the preservation and strengthening of their health on the basis of education of a healthy person in the educational space, in the process of which various social institutions and the student themselves are involved. The research is based on secondary schools in Vozhegodsky (experimental) and Kharovsky (control) districts of the Vologda region. In the experimental Vozhegodsky district, the developed model of healthy personality education in the educational space was tested. The empirical study was attended by 1825 the students of educational institutions of these regions. The sample for the study was carried out by random selection from lists of students in grades 5-11. Definition of level of formation of subjective position of students in relation to the preservation and strengthening of their health from the list of organizations in the experimental and control municipalities in the sample had carried out a survey using the developed test-questionnaire made up by the method of free choice of the presented answers, proposed N. E. Surkovoy, at the beginning, middle and end of the experiment. The obtained data were compared with objective data on the health status of students in health groups obtained from medical records of children's clinics. Over the period from 2004 to 2018, the indicator of a high level of formation of the subject position of students in grades 5 of Vozhegodsky district in relation to the preservation and strengthening of their health increased by 2.5 times, students in grades 11-3 times; in the control Harovsky district in grades 5, this indicator increased by 1.6 times, in grades 11 – 1.4 times. The number of children with the first group of health in educational institutions of Vozhegodsky district increased by 8.2% during the experiment period. In the control Khar district, the number of children with the first health group decreased by 7.7% over the same period. The obtained data confirm that the introduction of new approaches to the design and implementation of comprehensive programs for the education of a healthy person based on the interaction of various social institutions at the level of educational organizations, rural settlements, municipalities ensure the effectiveness of the formation of the subjective position of students in relation to the preservation and strengthening of their health and improve the objective indicators of their health.

Classification of Regions of Ukraine by The Level of Social Tension

The analysis of indicators that reflect changes in the social, economic and political spheres in recent years has shown their significant deterioration and the possibility of growing social tensions in the regions of Ukraine. The purpose of the study is to classify the regions of Ukraine according to the level of formation of social tensions and to determine anticipative measures aimed at preventing the creation of crisis situations. The article proposes a methodical approach to the classification of regions using the methods of cluster, discriminant analysis and analysis of variance according to the level of social tension, which includes two main stages: substantiation of the system of socio-economic indicators characterizing the level of social tension; selection and substantiation of models of classification of the regions. Within the first stage of the methodical approach the system of indicators which reflect changes in social, economic and political spheres of Ukraine in modern transformational conditions was constructed. Within the framework of the second stage of the methodical approach on the basis of cluster analysis the classification of regions according to the level of formation of social tension was carried out. The classes of regions were selected: with a low level of formation of social tension; with an intensified level of formation of social tension; with a high level of formation of social tension. The results of the study showed that the number of regions in the class with a high level of social tension is constantly growing and, unfortunately, the number of regions with high socio-economic development is decreasing. The classification of regions made it possible to determine the list of preventive measures that can reduce the losses of the state associated with the containment of possible crises in the social sphere. However, the article also states that such a list of activities should take into account the specifics of the region that is part of each class

КРИТЕРІЇ ТА РІВНІ СФОРМОВАНОСТІ ЕМОЦІЙНОЇ КОМПЕТЕНТНОСТІ МАЙБУТНІХ УЧИТЕЛІВ ПОЧАТКОВОЇ ШКОЛИ

The article considers the development of emotional competence of prospective elementary school teachers, which is understood as a set of views, values, acquired knowledge, skills in the emotional sphere, their understanding, expression, regulation and allows you to successfully organize the educational process on an emotional basis, empathy, respect, cooperation with schoolchildren, their parents, colleagues, to realize themselves in personal and professional activities. The purpose of the article is to study and theoretically substantiate the criteria, levels and indicators of the formation of emotional competence of future primary school teachers. To solve the problem, methods of analysis of psychological and pedagogical literature, systematization and generalization of theoretical material, study of experience were used. On the basis of structural components of the specified phenomenon cognitive, value, activity criteria are developed. Cognitive criterion is characterized by the presence and completeness of knowledge about emotions, feelings, emotional states, ways of their expression, causes, age features of the emotional sphere of primary schoolchildren, awareness of technologies influencing the emotional state of schoolchildren, ways to manage their emotions. The value criterion includes recognition of the value of emotions in professional and personal spheres, acceptance of own emotional experiences and feelings of schoolchildren, their parents, colleagues, humanistic attitude to communication, interaction with participants of educational process, need to be emotionally competent teacher, motivation to succeed in pedagogical activity. The activity criterion includes a set of skills and abilities of the student to adequately perceive schoolchildren' emotions, understand their feelings and their own emotional state, express their own emotions, manage them, establish productive communication, organize interaction with schoolchildren, their parents, colleagues, make a constructive impact on participants' emotional state, educational process, motivate, stimulate them, prevent conflicts, apply constructive strategies to resolve them. Given the degree nature of the acquisition of competence, the low, medium and high level of formation of emotional competence of prospective primary school teachers is determined, their characteristics are described. Keywords: emotional competence, prospective elementary school teacher, criteria, indicators, levels, formations.

ФОРМУВАННЯ ЦІННІСНИХ ОРІЄНТАЦІЙ МАЙБУТНІХ ПЕДАГОГІВ-ХОРЕОГРАФІВ У ПРОЦЕСІ МЕТОДИЧНОЇ ПІДГОТОВКИ

The modern philosophy of art and pedagogical education considers the idea of humanization of the educational process in higher education institutions as leading and emphasizes the need to form future teachers’ values, which are evidence of personal maturity, psychological readiness for teaching. The high level of formation of professional qualities of the teacher’s personality, full disclosure of his individual, potential and personal capabilities provide active pedagogical activity. As a component of personality’s structure, value orientations are manifested in human activity as certain hierarchies of benefits that a person provides to material, social and spiritual values. Social values act for the teacher of choreography as strategic goals of his pedagogical activity, influence the content and direction of his needs, motives and interests. The aim of methodical training of future teachers-choreographers is to form the foundations of their professional culture, the ability to operate with knowledge and skills in the process of understanding the problems of teaching choreography, a holistic vision of the pedagogical process. As a result of mastering the theory and technology of art education, methodological training includes individual socio-personal experience of theteacher as a set of methodological knowledge and skills that allow him to identify a personal scientifically sound position in solving art and educational problems. Based on the synthesis of opportunities, pedagogical abilities, social activity, inclusion of the individual in pedagogical activity, the subject of activity with his position, professional plans, beliefs, behaviour, attitude to the results of his own activity and value orientations is formed.

CRITERIA, INDICATORS AND LEVELS OF SOCIAL RESPONSIBILITY OF THE FUTURE SOCIAL SPECIALISTS

The article substantiates the relevance of the study of social responsibility as a social phenomenon and characteristics (features, properties) of the individual at the present stage of development of society. Indicated that increased productivity depends on effective staff training, the implementation of which is a process in which evaluation of human resources, their characteristics plays an important role. The relevance of the study of formation of social responsibility due to the fact that she, as a character trait of an individual is manifested in all spheres of life of an individual and, in turn, appears as a criterion in the evaluation of its interaction with the other members of society. On the basis of the structural components of social responsibility of the individual (motivational, cognitive, and behavioral) developed criteria of its formation (motivational-value, cognitive-cognitive, activity and practical) and identified indicators reflecting the main criteria characteristics and include the possibility of measurement using appropriate techniques. It is characterized by low, medium and high levels of formation of social responsibility of future specialists of social sphere. It is indicated that the use of diagnostic tools in the process of professional training of future experts in social sphere will not only fully reveal their degree of readiness to perform professional duties, but in time to correct possible deficiencies. It is noted that future scientific research should focus on the study of positive foreign experience of formation of social responsibility of future specialists of social sphere.

ПСИХОТРАВМУЮЧІ ФАКТОРИ БОЙОВОЇ ДІЯЛЬНОСТІ

Along with gaining combat experience, military personnel involved in the Joint Force operation are physically and psychologically injured. By participating in hostilities, military personnel are in a situation that threatens their lives for a long time, they are indirectly experiencing the death, injury and injury of their fellow warriors, and psychological tension is maintained by constant negative expectations. Creating an effective system of psychological assistance and rehabilitation in the present day is possible only under the understanding of the stress factors of combat activity and their impact on the personality, behavior and moral and psychological status of the personnel. Purpose. Аnalysis of stress factors and their impact on the soldier's personality, his behavior and moral and psychological state. Methods . The theoretical methods of research were used to solve the problems set in the work: analysis of scientific sources on the problem of research, synthesis, comparison, generalization. Originality . For the first time, stress factors that negatively affect the psyche, behavior and moral and psychological state of the personnel involved in the operations of the Joint Forces have been analyzed and the need for further improvement of the system of psychological assistance and rehabilitation has been substantiated. Conclusion: 1. Therefore, the modern battle places high demands on the personnel of the troops (forces) and its moral and psychological status. Everyone perceives a life-threatening situation depending on their own understanding of the purpose of hostilities, values, the level of psychological and military training, the attitude to the enemy, colleagues, the level of confidence in the commanders, the level of team cohesion, etc. 2. Ingeneral, the effective activity of personnel in combat conditions requires: a high level of motivation of behavior to perform the assigned task; high level of formation of moral and combat qualities; military and professional skills; the ability to quickly adapt to the combat environment, the ability to overcome the impact of negative factors of combat, the coherence of military teams and more. 3. One of the effective tools for overcoming the psycho-traumatic factors of combat activity by the personnel of the Armed Forces of Ukraine and other components of the Defense Forces is the creation of an effective system of providing psychological assistance and rehabilitation, which should include psycho-diagnostic, psychotherapeutic, psychocorrective preventive measures, and using individual group forms of psychosocial work and be conducted at the strategic, operational and tactical level of military management. 4.We see prospects for further research in substantiating the recommendations for improving the system of psychological assistance and rehabilitation in the Armed Forces of Ukraine.

1 H-NMR metabolomics profiling of recombinant tobacco plants holding a promoter of a sesquiterpene cyclase.

Nicotiana tabacum is a plant model intensively used in the bio-engineering pharmaceutical industry as a platform to produce drugs and therapeutic agents. Currently, no information regarding the non-targeted metabolome of transgenic tobacco containing recombinant regulatory sequences is available. To compare the proton nuclear magnetic resonance (1 H-NMR) metabolomics profiling of a recombinant Nicotiana tabacum strain containing a promoter of a sesquiterpene cyclase from Capsicum annuum driving GUS expression, versus wild-type samples. Methodology The non-targeted 1 H-NMR metabolome was obtained and processed by principal component analysis (PCA) and orthogonal projection to latent structures discriminant analysis (OPLS-DA). The differential metabolites were quantified by quantitative NMR. PCA and OPLS-DA revealed 37 metabolites including 16 discriminant compounds for transgenic samples. Ethanol (0.4 mg g-1 ), the main differential compound, was exclusively detected in transgenic tobacco; however, high levels of formate (0.28 mg g-1 ) and acetate (0.3 mg g-1 ) were simultaneously observed in the same group of samples. Cembratriene-4,6-diol, an antitumour and neuroprotective compound, and capsidiol, a known phytoalexin, increased by about 30% in transgenic samples. In addition, the endogenous levels of the antioxidant caffeoylquinic acid isomers increased by 50% in comparison to those of wild-type tobaccos. Our results support the occurrence of metabolic differences between wild type and transgenic tobacco containing a promoter of a Capsicum sesquiterpene cyclase gene. Interestingly, the recombinant transgenic strain studied accumulated high amounts of added value compounds with biological activity.

Класифікація регіонів України за рівнем формування соціальної напруженості

A classification of regions of Ukraine by the level of formation of social tensions together with determination of preventive measures aimed at preventing the creation of crisis situations are carried out. It is proved that the socio-economic situation typical for Ukraine has deteriorated significantly. This is evidenced by the decline of a large number of international indicators that characterize the stability of the country’s development. The suggested in the article methodological approach to the classification of regions by the level of formation of social tensions includes two main stages: substantiation of the system of socio-economic indicators that characterize the level of social tension; selection and substantiation of models of classification of regions. The carried out analysis of the values of socio-economic indicators of each cluster allowed to allocate the following classes of regions by the level of formation of social tension: 1st class – increased level of formation of social tensions; 2nd class – low level of formation of social tensions; 3rd class – high level of formation of social tensions. Of particular importance for the research is the 3rd class, i.e., the class with a high level of formation of social tensions, which leads to a crisis. The regions of this class should have serious government support in the social sphere. The results of the research showed that the number of regions classified with high level of social tensions is constantly growing and, unfortunately, the number of regions where the social sphere is more developed is decreasing. It should be noted that this situation is extremely dangerous, because it can lead not only to social, but also economic and political crises. The carried out analysis of the status of region of each of the received classes provides the possibility to prevent aggravation of crises in the social sphere and determine the list of preventive measures that can lead to a decrease in losses both in terms of individual classes and in the State as a whole.

Геоинформационный анализ агломерации Кавказских Минеральных Вод: градостроительные и функционально-планировочные аспекты

The article presents the results of research on the formation and development of the functional and planning structure of the urban agglomeration of the Caucasian Mineral Waters, as an integral part of the settlement system of the Stavropol territory and the North Caucasus Federal district. Theoretically, the authors rely on the concept of a single settlement system and a reference frame as a combination of nodal and linear elements that Express the main features of the territorial organization of the region. The paper uses various sources of quantitative and qualitative information on the Stavropol territory as a whole, the region of Caucasian Mineral Waters and individual municipalities: results of sociological surveys of the population, census data, information about the current socio-economic and demographic situation of the territory, materials of state and departmental statistics, documents of territorial planning and urban planning, own observations and results of “field” studies of the territory. Based on these data, a General characteristic of the CMS agglomeration is given, the spatial organization of settlement is analyzed, and current trends in its development are determined. One of the results of the study is a geographic information model of the agglomeration, which sets its boundaries and composition, calculates the coefficient of development, and makes a demographic forecast for the agglomeration as a whole and for individual municipalities. The model of spatial organization of the territory was based on the planning framework of the region, including social, economic, environmental, and transport frameworks. The territory of the agglomeration, despite its high level of formation, differs in significant contrasts, which makes it possible to distinguish different zones within it by the level of urban development and the role in the agglomeration. Using the methods of geoinformation mapping, maps of the agglomeration boundaries and transport accessibility of its cores were created, as well as a perspective structural and planning model of the CMS region. The authors come to the conclusion that the design decisions for the development of territories within the CMS agglomeration, given in the documents of territorial planning and urban planning of municipalities, should be based on the main function of the region — ecological and resort, which gives it the status of a region of Federal significance. Therefore, the measures set out in the territorial planning documents of each municipality must be interconnected (both in terms of hierarchical subordination and in the General context of agglomeration development of the territory) for the sustainable development of municipalities and the entire agglomeration, the preservation of the environment and cultural heritage.

La interrelación entre las estrategias de afrontamiento y la competencia sociopsicológica de la personalidad de los estudiantes universitarios

In contemporary society characterized by socio-economic and political instability, the problem of studying the factors and mechanisms that contribute to the constructive resolution of life difficulties and counteracting their negative consequences is very important. This paper contains the results of an empirical study of the characteristics and relationships of students’ coping behavior with different levels of their socio-psychological competency. The research methods comprised the following: theoretical analysis, empirical research (testing), qualitative analysis of the obtained data, mathematical and statistical data processing (SPSS Statistics, Excel). The characteristics of indicators of socio-psychological competency were determined with the use of the technique for assessing socio-communicative competency, as well as a questionnaire that reveals the possibility of using socio-psychological skills by a person in difficult life situations. To study coping behavior, the following were used: “The ways of coping questionnaire” and “The youth coping scale”. The validity and reliability of the research results was ensured by the initial methodological positions, the use of tested tools, representativeness of the research sample, as well as mathematical processing of data with the help of software package for statistical analysis. The conclusions have been drawn that the basis of constructive mechanisms to overcome difficult life situations is a high level of formation of professional skills and abilities, introversion, motivation to achieve success, high intellectual development, moral standards, a high level of development of communication skills. It is these mechanisms that make it possible to resolve problem situations and tasks at work in a productive way. Their absence or a low level of development contributes to the dominance of situational methods of overcoming difficult life situations that impede professional formation and personal development.

МЕТОДЫ И ПРИЕМЫ ОБУЧЕНИЯ КИТАЙСКИХ СТУДЕНТОВ РУССКОЙ РАЗГОВОРНОЙ РЕЧИ

The article examines the problems and methods of teaching russian spoken speech at a chinese university, taking into account the ethnocultural characteristics of the chinese audience and the specifics of the chinese student education system. A system of methods and approaches is justified, which contributes to the effective mastery of russian spoken speech. The article describes the features of the chinese audience, complicating the mastery of russian spoken speech in the RCT lesson. The principles and exercises proposed in the article contribute to the organization of such an educational process that will ensure the achievement of a high level of communicative competence of chinese students, the author considers certain didactic techniques that allow achieving a high level of formation of foreign-language communicative competence, neutralization of passion and psychological barrier («psychological counseling», debates, «brainstorming», «fun pictures», comic dialogues, thematic autostoritelling, «black box», «director himself», roleplaying games, «lexical physical education», etc.). The article notes that the main way to overcome this is to use means, methods and techniques in the process of training based on the pedagogical impact of humor, the use of which should become an integral component of the process of teaching chinese students of oral speech and be consistently implemented in all aspects of this process: in the speech behavior of the teacher, in the selection of didactic material, in the typology of the proposed tasks. The author justifies the concept of lessons in colloquial speech as an «encyclopedia of life» and the need to expand the outlook of students by providing them with new information from the field of «background knowledge», not only aimed at expanding the lexical base, but also containing interesting information about psychological and cultural phenomena.

Evaluation of the effectiveness of the use of case-technology in teaching computer modeling of future teachers of informatics

Problem and goal. The article describes the problem of using case-technology in teaching computer modeling to future teachers of informatics. The relevance of solving this problem is determined by the need to find new approaches to combining the fundamental and applied training of future teachers in order to form a holistic competency that provides a solution to professional pedagogical problems. The purpose of this study was to design a model of training future teachers of informatics in the field of computer modeling using case-technology, as well as testing this model during a pedagogical experiment. Methodology. The basis of the developed methodological approach was the use of subject-oriented cases in teaching computer modeling to future teachers of informatics. This type of cases is considered as a set, which includes: 1) situational problem; 2) tasks, the implementation of which leads to the solution of the problem; 3) materials needed to complete tasks; 4) software tools for solving the problem. The model of training of future teachers of informatics using case-technology is considered as a set of target (formation of competence of the teacher of informatics in the field of computer modeling), content (the content of the course “Computer Modeling”) and process components (three stages of design, development and direct application of the subject-oriented case of computer modeling in the classroom). To assess the effectiveness of the case-technology application, a pedagogical experiment was conducted, involving the implementation of training in experimental and control groups. Results. The article presents the results of an experiment conducted at the Volgograd State Socio-Pedagogical University. During the experiment in the control and experimental groups, a course of computer modeling was implemented with the preservation of the content, but with the use of case-technology in the experimental group. Criterion evaluation of the effectiveness of the formation of competence of the teacher of informatics in the field of computer modeling was carried out in the subject and research aspects. The results of the experiment showed that in the experimental groups increased the number of students represented at high, as well as medium and high levels of formation of both the subject and research component of the competence. Conclusions. The study showed that the proposed approach to the use of case-technology provides high results. The obtained and statistically confi data of the experiment allow us to speak about the effectiveness of the use of case-technology as a means of teaching computer modeling to future teachers of informatics.

PSXIII-25 Comparative analysis of state of the neurosecretary system of pink salmon, Oncorhynchus gorbuscha walb. on different stages of ontogenesis

Abstract The preoptic-pituitary neurosecretory system (PPNS) plays a key role in the regulation of reproduction, spawning, osmoregulation and fish growth. This study aimed to find out the development features of the PPNS in pink salmon in connection with gonadal sex differentiation and spawning. A comparative morphometric analysis of all parts of the system was carried out in juveniles aged 3–4 months and adults during the spawning season. The ratios of the areas were calculated for the PPNS different segments on the sagittal sections: the cellular parts of the preoptic nucleus, the cyto- and karyometric characteristics of neurosecretory cells. The complex morphometry of neurosecretory, glial and vascular elements in the neurohypophysis was carried out. It was found that during seaward run and the completion of sex differentiation, the main sections of the PPNS were already fully formed and the ratio of all parts of the preoptic nucleus in juveniles and adults was not significantly different (р< 0,05). In juveniles, compared with adults, the relative area of the neurohypophysis was significantly higher (P < 0.05), and level of relative development of the capillary network, the length of neurohemmal contacts and organ hyperemia were comparable. It was shown a high level of formation and functioning of PPNS in juveniles, as well as its important role during seaward run and early gonadogenesis.

Criteria, Indexes And Levels of Formed of Readiness of Future Junior Specialists of Physical Culture and Sport to Communicative Cooperation in Professional Activity

In the article certainly and criteria, indexes and levels of formed of readiness of future junior specialists of physical culture and sport, are reasonable to communicative cooperation in professional activity. With the purpose of determination of criteria of formed of the investigated quality correlation of concepts is set "criterion" and "index". A criterion is certain as more stable, and index dynamic.
 Such criteria of readiness of future junior specialists of physical culture and sport are certain to communicative cooperation: motivational, cognitive, communicative-active and emotionally-evaluation, that is directly correlated with the components of the investigated quality. A motivational criterion includes for itself such indexes: communicative values; communicative interests; communicative necessities .
 Indicators of the cognitive criterion are: knowledge of the basics of communication; knowledge of the basics of professional communication. The indicators of the communicative criterion are: communicative thinking; communicative behavior. The indicators of the emotional-evaluative criterion are: self-control and self-regulation (establishing emotional contact during the conversation, assessing the interlocutor’s mood, managing their own emotional state during the conversation, assessing the emotional state of the partners during communication, assessing their own communicative competence).
 A low, satisfactory, sufficient and high level of formation of readiness of junior specialists in physical education and sports for communicative interaction in professional activities is established.

Project Activities in the Context of the Implementation of State Standards of the New Generation

Federal state educational standards of higher education contain requirements that indicate the priority direction of the formation of the competencies of modern graduates. Competence-based educational paradigm necessitates the search and implementation of ways to promote the formation of a qualified specialist. The implementation of project activities in higher education is revealed as the leading direction of activity, ensuring the achievement of a high level of formation of competencies of students of higher educational institutions. The purpose of the article is to consider the project activities of students of higher education in the conditions of implementation of state standards of the new generation. The authors present the characteristics of the project activity, its typology, set the possibilities, the criteria for evaluating the implementation of project activities. As an example, presents a large-scale project of higher school of organization of independent work of students, which includes relevant conditions, educational landscape, allowing students to participate in various projects, thereby forming respective competences laid down in the standard. The project activity of students in the framework of this project develops at a higher level.

Adaptive Responses in the Metabolism of <i>Escherichia coli</i> in View of Gene Expressions under Aerobic and Micro-aerobic Condition

The major aims of biology to understanding life at a systems level. Escherichia coli is a metabolically versatile bacterium able to respond to changes in environmental factors availability. The effect of pH downshift on fermentation characteristics was investigated in a continuous culture of Escherichia coli at aerobic and micro-aerobic conditions. Regardless of oxygen availability, higher levels of acetate were associated with lower biomass yields and lower glucose consumption rates at pH 5.5 as compared to the observations made at pH 7.0. Observed gene expressions indicated that the down- regulation of the glucose uptake rate corresponded to the down-regulation of ptsG gene expression which in turn was caused by the up-regulation of mlc gene under the positive control of Crp. In accordance with up-regulation of arcA gene expression at acidic conditions, the expressions of TCA cycle-related genes such as icdA and gltA, and the respiratory chain gene cyoA were down-regulated, whereas cydB gene expression was up-regulated. Decreased activity of the TCA cycle caused more acetate formation at lower pH levels. Under micro-aerobic condition, higher levels of formate and lactate were produced at lower pH due to up-regulation of pflA, yfiD and ldhA genes. Meanwhile, lower levels of ethanol were produced due to the down-regulation of adhE gene at lower pH, as compared to the observation at neutral pH. The combined effect of pH and temperature on gene expression was also investigated and observed that decreases in the specific glucose consumption rate were associated with increases in the specific acetate production rate. This type of information is useful for the production of recombinant proteins, bio-molecules, simultaneous saccharification and fermentation (SSF) and strain improvement.

THE FORMATION OF TRANSLATORS’ RESEARCH COMPETENCE AT THE UNIVERSITIES OF UKRAINE

This study explores the essence and the structure of the translators’ research competence, as well as the development of the system for its formation. We have developed a system of 12 interrelated segments of the research skills of translator: the development of the initial research base, the study of theoretical information, data collection (translation), data collection (didactics), data processing, pedagogical model of the experimental forming stage, argumentation of personal position, generalization of experimental data, forecasting the research prospects, presenting the research results, publication of research results, self-esteem. In accordance with the scientific positions, we offered to evaluate the level of formation of research skills in accordance with the criterion of the performance accuracy of skills presented in each segment. The obtained data revealed low, medium, high levels of formation of research skills. We have evaluated the level of students’ knowledge about the main categories of research activity. In order to form the research competence of translators, we have developed the tasks aimed at the formation of research skills, knowledge about the organization of research activities in the field of translation studies.

Formation Of Emotional-Volitional Culture Of Future Policemen In The Course Of Vocational Training

The article is devoted to revision of a problem of formation of the emotional-volitional culture of future policemen in the course of vocational training. It is predetermined by the increase of intensity and force of stressful factors which influence negatively on their mentality, moral and physical state during performance of professional duties. At the stage of theoretical development of a problem was made a hypothesis that formation of emotional-volitional culture of future policemen will be effective if in the course of their vocational training provide the following issues: 1) development of resistant motivation in cadets to mastering emotional-volitional culture as professionally significant quality; 2) application of pedagogical tools in educational process (forms, methods, means) which requires demonstration of emotions and volitional qualities of the personality; 3) stimulation of cadets to self-improvement of emotional-volitional culture. For testing the made hypothesis were used the following methods: theoretical (philosophical, psychological and pedagogical analysis with the purpose of conceptual construct determination and grounds of pedagogical conditions of formation of emotional-volitional culture of future policemen); empirical (questioning, testing, conversations, polls, pedagogical experiment); mathematical statistics (arithmetic mean of , Pearson criterion χ?). 358 cadets from Kharkiv National University ofInternal Affairsparticipated in a research. They formed the experimental group (180 persons) and the control group (178 persons).Results. The efficiency of pedagogical conditions implementation of formation of the emotional-volitional culture of future policemen in the course of vocational training was proved during the experimental work which included classes, extracurricular educational activities, in particular, the educational club «Fan of extreme» and also practical training of cadets. In a general number of cadets with the high level of formation of emotional-volitional culture in the experimental group increased by 30% whereas in a control group the appropriate increase was only 12%. At the same time, the number of cadets with the low level of formation of emotional-volitional culture decreased in the experimental group by 24%, in control group by 18%.Conclusions. Defined pedagogical conditions of formation of the emotional-volitional culture of future policemen were checked by scientific experiment and could be realized in the course of vocational training at the higher education establishments of Ministry of Internal Affairs of Ukraine.

Study of bilineage differentiation of human-bone-marrow-derived mesenchymal stem cells in oxidized sodium alginate/N-succinyl chitosan hydrogels and synergistic effects of RGD modification and low-intensity pulsed ultrasound

The level of formation of new bone and vascularization in bone tissue engineering scaffold implants is considered as a critical factor for clinical application. In this study, an approach using an RGD-grafted oxidized sodium alginate/N-succinyl chitosan (RGD–OSA/NSC) hydrogel as a scaffold and low-intensity pulsed ultrasound (LIPUS) as mechanical stimulation was proposed to achieve a high level of formation of new bone and vascularization. An in vitro study of endothelial and osteogenic differentiations of human-bone-marrow-derived mesenchymal stem cells (hMSCs) was conducted to evaluate it. The results showed that RGD–OSA/NSC composite hydrogels presented good biological properties in attachment, proliferation and differentiation of cells. The MTT cell viability assay showed that the total number of cells increased more significantly in the LIPUS-stimulated groups with RGD than that in the control ones; similar results were obtained for alkaline phosphatase activity/staining and mineralized nodule formation assay of osteogenic induction and immunohistochemical test of endothelial induction. The positive synergistic effect of LIPUS and RGD on the enhancement of proliferation and differentiation of hMSCs was observed. These findings suggest that the hybrid use of RGD modification and LIPUS might provide one approach to achieve a high level of formation of new bone and vascularization in bone tissue engineering scaffold implants.

Kinetics of naphthalene metabolism in target and non-target tissues of rodents and in nasal and airway microsomes from the Rhesus monkey

Naphthalene produces species and cell selective injury to respiratory tract epithelial cells of rodents. In these studies we determined the apparent Km, Vmax, and catalytic efficiency (Vmax/Km) for naphthalene metabolism in microsomal preparations from subcompartments of the respiratory tract of rodents and non-human primates. In tissues with high substrate turnover, major metabolites were derived directly from naphthalene oxide with smaller amounts from conjugates of diol epoxide, diepoxide, and 1,2- and 1,4-naphthoquinones. In some tissues, different enzymes with dissimilar Km and Vmax appeared to metabolize naphthalene. The rank order of Vmax (rat olfactory epithelium>mouse olfactory epithelium>murine airways≫rat airways) correlated well with tissue susceptibility to naphthalene. The Vmax in monkey alveolar subcompartment was 2% that in rat nasal olfactory epithelium. Rates of metabolism in nasal compartments of the monkey were low. The catalytic efficiencies of microsomes from known susceptible tissues/subcompartments are 10 and 250 fold higher than in rat airway and monkey alveolar subcompartments, respectively. Although the strong correlations between catalytic efficiencies and tissue susceptibility suggest that non-human primate tissues are unlikely to generate metabolites at a rate sufficient to produce cellular injury, other studies showing high levels of formation of protein adducts support the need for additional studies.