Landslides are prevalent in the Ethiopian highlands, particularly in the east Gojjam zone, which is highly affected by landslide problems. This research was carried out in the east Gojjam zone, northwestern Ethiopia. The study area is part of an economically important area in the country, and it is the main source of water for the Grand Ethiopian Renaissance Dam (GERD). The main objective of this work was to undertake a detailed inventory of past landslide locations and prediction of present and future landslide hazards, as well as the preparation of a landslide zonation map in the East Gojjam zone by using the Analytical Hierarchy Process (AHP) with the GIS technique. The parameters used for this study were slope degree, slope aspect, land use and land cover, road proximity, rainfall, lithology, altitude, and river proximity. The various causative parameters were collected from the field, and suitable modifications were made to the thematic maps. Finally, the ratings for various parameters were used as the basis to prepare the LHZ map in GIS windows. The landslide susceptibility and inventory mapping were produced in the GIS environment. The results of the study show that the main driving factors for the landslide hazards in the area were river proximity, rainfall, and manmade activities. Validation of this LHZ map revealed that more than 80% of past landslides match within the "high hazard zone" and reasonably accepted the rationality of the adopted methodology. The considered parameters, as well as their evaluation of the production of LHZ-Map, were confirmed. The produced landslide inventory map is very important for urban planners, agricultural studies, environmentalists, and future landslide hazardous prevention and mitigation strategies.