Resistivity ρ(T) and Hall coefficient RH(T) in magnetic fields H up to 14T were studied in superconducting (Tc=3.3K) LaRu4Sb12 single crystals disordered by fast neutron irradiation. Atomic disordering leads to increase in residual resistivity ρ0, decrease of Hall number and suppression of superconductivity. The upper critical field slope −dHc2/dT increases approximately linear with ρ0. The irradiation effects are almost recovered after annealing at 500°C. The observed radiation-induced effects in LaRu4Sb12 are compared with those in PrOs4Sb12 in terms of unconventional mechanisms of superconductivity.