In the present real-time world, due to the improvements and innovations of System on Chip (SoC) applications, there is a requirement to integrate multiple technology design topologies. The electronic system design is classified as analog, digital, and mixed-signal design. The comparator is the major building block used in the datapath of System on Chip (SoC) application device. The usage of these devices depends on not only functionality but also on the non-functionality parameters considering different performance estimation metrics. The nonfunctional performance metrics for a transistor level design depends on the number of transistors, switching activities of logic level voltages and delay between input and outputs. These performance metrics are improved by considering the multiple logic families for multiple output generations instead of using a single logic family topology. The comparator is the major component in the arithmetic circuits for SoC applications and can be realized by using various design topologies. The vividly used topologies are Conventional CMOS logic, Pass Transistor Logic (PTL), Gate Diffusion Input (GDI) Logic, Stacking technique, Quantum-dot cellular automata, etc. The selection of the design topology for the comparator is made based on the non-functional parameters. The performance of non-functional parameters is improved by combining the topology architectures of different design techniques. In this paper, the comparator is designed using conventional CMOS logic, PTL, GDI, and a hybridized topology for best performance and the same is implemented using 45nm technology. These circuits are designed by using Cadence Virtuoso Electronic Design Automation (EDA) design tools. Non-functional performance parameters are analyzed for different topologies. Index Terms: VLSI Design, Comparator, Datapath, EDA tools, CMOS Logic, GDI Logic, PTL Logic.