Renalase decisive enzyme about the postoperative term hypotension after coronary artery bypass graft surgery

Aydin S,Eren Mn

doi:10.15761/bhc.1000131

Abstract

Renalase decisive enzyme about the postoperative term hypotension after coronary artery bypass graft surgery

Highlights

Hypotension, or decreased blood pressure, is a common complication seen during and after open heart surgery [1,2]
That measurement of renalase may have practical utility for the monitoring of catecholamines in order to better control dopamine infusion amount and hypotension and may give an idea to the operators about whether hypotension develops in the postoperative term or not
**Normal tension after coronary artery bypass grafting without treatment dopamine; ***Hypotension developed after coronary artery bypass grafting and treated with dopamine; ap < 0.05 compared with and without hypotension developed after coronary artery bypass grafting

Summary

Result

When the patients were compared in terms of number of grafts used (2.7±0.3), perfusion time (97.4±9.8 min.) and aortic cross clamp duration (56.9±4.9 min.), there was not any difference between the patients who did and did not develop hypotension. Heart rate was significantly higher in patient whom developed hypotension after coronary artery bypass graft surgery. CVP (mmHg) and MPAP (mmHg) values were similar in groups (Table 1). As expected, diastolic and systolic blood pressure were lower in hypotension as compared with control subject’s values. Low catecholamine and high renalase levels were detected in the comparison of patients who developed hypotension in the 6-8th hours of the postoperative term as compared with patients who did not develop hypotension after coronary artery bypass graft surgery and healthy subjects. **Normal tension after coronary artery bypass grafting without treatment dopamine; ***Hypotension developed after coronary artery bypass grafting and treated with dopamine; ap < 0.05 compared with and without hypotension developed after coronary artery bypass grafting

Conclusion

Introduction

Material and method

Findings

Discussion