Abstract
Leukemic conversion in case of Burkitt’s lymphoma from non-endemic region
Highlights
Burkitt’s lymphoma is rare neoplasm which may be either be endemic involving mandible and maxilla and associated with Epstein Barr virus or sporadic which is associated with EBV in only 1020% of cases [1,2]
Immunohistochemistry on bone marrow biopsy showed positivity of Ki-67 in more than 95% blasts
EBV is associated with endemic cases but AIDS related malignancies constitute 2.4-20% of Burkitt’s lymphoma [6]
Summary
Burkitt’s lymphoma is rare neoplasm which may be either be endemic involving mandible and maxilla and associated with Epstein Barr virus or sporadic which is associated with EBV in only 1020% of cases [1,2]. The leukemic conversion of Burkitt’s lymphoma without any tumour mass is considered to be unusual and that too in immunocompetent patient [3,4]. The present case is being reported due to its unusual presentation with absence of any abdominal or facial mass but with only bone marrow involvement in non-endemic region. The case highlights an important feature of leukemic conversion of Burkitt’s lymphoma in immunocompetent patient which is rarely reported in literature.
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