ABSTRACT Introduction Various anthropometric measurements have been used to determine the size of maxillary anterior teeth. However, which anthropometric measurement is the most reliable indicator to determine the width of maxillary anterior teeth remains unclear. Aims and objectives To evaluate which anthropometric measurement is the most reliable indicator in determining the width of maxillary anterior teeth. Materials and methods An electronic search was conducted for scholarly articles discussing various anthropometric measurements used for determination of width of maxillary anterior teeth, written in English or translated into English listed with PubMed, Cochrane Library, ScienceDirect, Wiley Online Library, and Google scholar databases. The search strategy yielded 119 articles. Out of them, 70 were excluded following reading of abstract, and 49 were selected for full-text reading. Of these, 21 were excluded based on exclusion criteria. Finally, 28 articles were included for final search. Due to heterogenicity of studies, a meta-analysis was not performed. Results High degree of correlation was seen between interalar width (IAD), interpupillary distance (IPD), bizygomatic width (BW), and width of maxillary anterior teeth, in Indian population, whereas in Saudi population, intercanthal distance (ICD) has high degree of correlation to the width of maxillary anterior teeth, and in Brazilian (mulatto and blacks) population, high degree of correlation was seen between intercommissural width (ICOW) and width of maxillary anterior teeth. Conclusion The anthropometric measurement used depends on the population group in which it is being used. There is no single anthropometric measurement that can be used to determine the width of maxillary anterior teeth. Hence, more studies with large sample size and different population groups need to be conducted. Clinical significance In Indian population, high degree of correlation was seen between IAD, IPD, BW, and width of maxillary anterior teeth. The results of the previous study should be validated by including a large population size spread over entire Indian subcontinent. This would also help to generate multiplication factor for various anthropological measurements for use limited to the Indian population. How to cite this article Jain AR, Nallaswamy D, Ariga P, Ganapathy DM. Determination of Correlation of Width of Maxillary Anterior Teeth using Extraoral and Intraoral Factors in Indian Population: A Systematic Review. World J Dent 2018;9(1):68-75.