Ushna Virya Research Articles

A Review on the Probable Mode of Action of Agnikumara Rasa (B.R Jwaradhikara) - An Ayurvedic Herbal Formulation With Multifaceted Action

In Ayurveda, Agnimandya (reduced digestive power) is considered as a root cause for all diseases. Agnikumara rasa (B.R Jwaradhikara) is a well-known Ayurvedic formulation used by Ayurvedic practitioners that increases Agni (digestive fire) and is indicated in various diseases with specific Anupana (adjuvant). There are 6 constituents in this formulation and is indicated in the management of vitiation of Kapha and Vata humor. On analysing the properties of the ingredients, it was found that it is predominant of Katu rasa (pungent taste), Thikta rasa (bitter taste), Laghu (light), Ruksha (dry), Tikshna (sharp) properties, Ushna virya (hot potency), Katu vipaka (pungent taste after bio-transformation). These therapeutic properties are responsible for pharmacological actions of the formulation. This review paper is an attempt to analyse the mode of action of this formulation which gives a deep insight about the usage of the formulation with a better understanding, so that the physician can use the formulation according to his logic in conditions other than indicated.

Clinical Evaluation of a Novel Formulation: Banarasi Tambula (Piper Betle L.)Patra Swarasawith Bhimseni Karpura Choorna (Dryobalanops Aromatica Gaertn.F.) in the Management of Kaphaja Kasa (Productive Cough)

During high waves of SARS Covid-19 and post-covid period there is increase in respiratory tract diseases in population. It was noted that Ayurvedic management was having encouraging results with comparative cure rate higher and with lesser complications. ‘Tambula Patra (Betel leaf) along with Bhimseni Karpura’ (Camphor) is one of the commonest combination drug of choice used especially in Kapha dominant Kasa by Vruddha Vaidyas from a long period of time. The preparation was named as “NagaSphatika” based on combination of basonym and synomym of components. It was made using Banarasi Tambula leaf’s Swarasa with Bhimseni Karpura as a Prakshepa (additive) in liquid form dispensable medicine for Kaphaja Kasa. Single arm Clinical study was undertaken to evaluate its efficacy in Kaphaja Kasa in 52 patients. NagaSphatika was significantly effective in the management of Kaphaja Kasa. The disease involves Kapha and Vata dosha dushti predominantly. Tambula due to its Katu, Tikta, Kashaya rasa, Ushna Virya, Katu Vipaka, Laghu, Ruksha, Tikshna and Vishada guna pacified Kapha Dosha leading to removal of Avarodh in the Srotas bringing Prakruta gati to Vata Dosha and also ignites Agni which further digests the Ama or Dushta Rasa Dhatu. Bhimseni Karpura having Tikta, Katu Rasa, Madhura Rasa and Katu Vipaka, Laghu, Tikshna Guna alleviates Kapha Dosha by its Lekhan Karma occurring in Kantha and Urah. NagaSphatika had significant effects on signs and symptoms of Kaphaja Kasa, hence is effective in its management

A Critical Analysis on A Multipotent Drug Chandraprabha Vati - Review Article

ChandraprabhaVati is a very commonly used herbo-mineral preparation in dayto-day practice being efficient in various disorders mostly genitor-urinary ones. Chandraprabha Vati is available in various ayurvedic texts with different preparations and different ingredients. The preparation, described by Sarangdhar Samhita and accepted by AFI, is being taken for a critical review of its properties, actions and its clinical efficacies in different diseases. It is made up of 37 ingredients with Shilajit and Guggulu present in maximum quantity 32 parts each. It is katu (73.38%) tikta (69.78%) in rasa, laghu (76.98%) ruksha (74.10%) in guna, ushna virya (70.50%), katu vipaka (69.06%) and tridosha shamak predominantly Vatakapha shamak (91.37% and 84.89% respectively). This preparation is indicated in Prameha, Mutravahasrotaja vyadhi, Anaha, Shoola, Shwasa, Kasa, Shukradosha, Pandu, Kamala, GudagataVyadhi, Netraroga, Dantaroga, Kushtha and various other diseases as mentioned in different texts. Clinical studies have also proved its efficacy in various diseases. It is antidiabetic, anti-inflammatory, anti-tumour, renal protective, hepato-protective, effective in jaundice and genitor-urinary diseases like UTI, dysmenorrhoea, PCOD, female infertility, etc. and many diseases are still left to be explored. Chandraprabha Vati is a multifaced drug and can be used in a variety of ailments successfully.

Vatari guggulu and mahaushadhi kwatha in amavata (Rheumatoid Arthritis): An open-label, single-arm clinical study

Introduction: Amavata (rheumatoid arthritis [RA]) is a painful disease which is caused due to vitiated vata and Ama. Amavata has been correlated to RA in modern medical parlance. The prevalence of RA in adults of the developed world is around 0.5%–1%, amid which around 40% are registered disabled within 3 years, while around 80% are moderate to severely disabled within 20 years. Based on the pathogenesis of Amavata, the treatment shall be focused mainly on ama-pachana (digestive) and agni dipana (carminative). Most of the ingredients in vatari guggulu and mahaushadhi kwatha are katu (pungent), tikta (bitter) rasa (taste), and ushna virya (hot potency), which helps in ama pachana (digestive) and agni dipana (carminative) action. Ingredients namely gandhaka (Sulphur), guggulu (Commiphora mukul), haritaki (Terminalia chebula), and amalaki (Emblica officinalis) are having rasayana property; while shunti (Zingiber officinale), guduchi (Tinospora cordifolia), guggulu, haritaki, vibhitaki (Terminalia bellerica), and amalaki have anti-inflammatory property. Methods: Thirty patients were administered vatari guggulu 1 tablet (1 g) along with mahaushadhi kwatha 15 ml thrice daily after food with warm water as anupana (adjuvant) for 15 days. Ordinal data were analyzed with Friedman's test followed by Wilcoxon sign rank test as post hoc; continuous data were analyzed with repeated measures ANOVA after applying Bonferroni correction with paired t-test as post hoc. Results: There was statistically significant improvement in the primary outcome measures, in disease activity and functional ability indices. Conclusion: Vatari guggulu and mahaushadhi kwatha are effective in the management of Amavata.

An Exploratory Study of Clinical Efficacy of “Shwasahar Dashemani” in Shwas Roga

Shwasa is considered as the most serious disease in Ayurveda and stated that none other disease kills as instantaneously as Shwasa. A high prevalence of respiratory disorders was observed in Delhi, 30.5 % people are affected the respiratory ailments. Shwasahar Mahakasayais one of the significant Ayurveda group of medicine which helps in improving Respiratory diseases. Study is todrill down the possible effect of Shwasahar Mahakasaya based on distribution of active principles explained in Ayurveda classical text. Percentage criteria is being analysed to get the clarity about the reason behind desired output. Rasa, Guna, Viryaand Vipakathese attributes are analyzed based on their component distribution. Distribution of dominating attributes among 10 Plants indicated in Shwashhar Mahakasaya are Katu Tikta Rasa, Laghu Guna, Ushna Viryaand Katu Vipaka. Results found out of the study is 31.82 % Katu Rasa, 36.36 Tikta Rasa, 43.48% Laghu Guna, 60.00% Ushna Viryaand 60.00% Katu Vipaka. Ushna Virya of the drugs is responsible to alleviate Vataand the remaining other factors Laghu Guna, Katu Tikta Rasaand Katu Vipaka along with Ushna Viryais responsible to alleviate Kapha. Equal potency in Rasapanchaka will produce final result in sequential manner where each aspect lined up with basic effects of Rasa. That is the best possible reason to get the great outcome through Shwashar dashemani.

UNDERSTANDING THE THERAPEUTIC AND PHARMACOLOGICAL EFFECTS OF COMMI-PHORA MUKUL (GUGGULU): A CRITICAL REVIEW

Guggulu has been a key element in the ancient Indian Ayurvedic system of medication. It has been used extensively by Ayurvedic Acharya for thousands of years to treat a large variety of disorders, besides its use in the pharmaceutical and perfume industries. Guggulu is a gum or resin extracted from the plant Commiphora mukul or Guggulu tree. Guggulu is a shrub or small tree belonging to Burseraceae family. a small perennial tree or shrub up to 1.2-1.8 m high, occurring in rocky tracts of Rajasthan, Barar, Khandesh, Maisoor, Kathiyabad, Belari. Exudate is collected during the winter season by making the incisions in the bark or summer, falling from the bark itself1. Guggulu has 5 types that are- Mahishaksha, Mahaneel, Kumuda, Padma, Hiranya. Guggulu is Vishad (non- unctuous), Tikta (bitter), Ushna Virya (hot in potency), increases Pitta, Sara (laxative), Kashaya (astringent), Katu (pungent) in taste, Katu in Vipak (pungent after digestion), Ruksha (causes dryness) and Laghu (light). Chemical compositions of Guggulu are volatile oil, resins and gum, Guggul sterole, Z-guggul sterone, E-guggul sterol-I, II and III, Sesasmine, Cholesterol, Mukolol and other steroids. It has Shothhar, Vedanasthapan, Vranshothan, Vranaropan and Jantughna effects. It uses as an external application in Aamvata, Katishul and Sandhishul. Keywords: Aamvata, Commiphora mukul, Guggulu, Kushtharoga, Sopha, Medoroga

A clinical study to evaluate the efficacy of Shatyadi Yoga in the treatment of Tamak Shwasa (Bronchial Asthma): Single case study

Bronchial Asthma is a chronic inflammatory disease of the Respiratory airways characterized by an increased responsiveness of the tracheobronchial tree to a variety of stimuli. In ayurveda Tamak Shwasa vyadhi is related with the derangement of the Pranavaha Shrotas. Tamak Shwasa is Pittasthana Samudhabhava and Kapha Vataja dosha vyadhi. The proposed study was conducted to access the efficacy of Shatyadi Yoga in the management of Tamak Shwasa. In modern science, there is no permanent cure for Bronchial Asthma.That is why it is the necessity to search for safe and effective herbal yoga in Asthma. The drug Shatyadi Yoga indicate the dominance of Katu, Tikta and Kashaya rasa, Laghu, Tikshna Guna, Ushna virya and Vata Kapha shamak karma. Shatyadi Yoga act on Pranvaha Shrotas thereby pacifying the symptoms in Tamak Shwasa.

CRITICAL REVIEW OF JYOTISHMATYADI YOGA IN NASHTARTAVA

The female undergoes dramatic monthly hormonal changes during each menstrual cycle affecting her emotional and physical state. During these changes sometimes she suffers from some gynaecological problems Nashtartava is one of them. As per classics, Nashtartava is considered as an Avaranajanya Vyadhi in which female suffers from Yathochita kale Adarshanam (Delayed menses/absence of menses), Alparta (scanty flow) and Yonivedana (painful menses). This condition can be compared with oligomenorrhoea or secondary amenorrhea. The ratio of such kinds of menstrual disorders is rising day by day which becomes a precursor of other health issues like infertility, mental and physical stress, etc. Oligomenorrhoea or infrequent menstruation, usually present in a woman with secondary symptoms like acne, obesity, dandruff, infertility etc. so treatment of Nashtartava is very necessary. For its treatment, the use of Agneya and Vata Kapha Shamaka Dravya is mentioned in the classics. Acharya Bhavmishra indicates the use of Jyotishmatiyadi Yoga for the management of Yonidosha along with Nashtartava. Jyotishmatyadi Yoga having Katu, Tikta Rasa, Tikshana Guna, Ushna Virya and Katu Viapaka and Vata Kapha shamaka property so effectively act on Nashtartava. Keywords: Nashtartava, Oligomenorrhoea, Jyotishmatyadi Yoga, Artava

A Review- Learning and Memory activity of Brahmyadi Ghrita

Brahmyadi Ghrita (BG) is one of the formulations recommended in Ashtangahridya Balrogadhikara as medhya & Smritivardhak. It contains 8 ingredients Brahmi, Kushta, Sariva, Pippali, Vacha, Sidhartaka, Goghrita, Saindhav. These are mainly having Medhya, Rasayana, Krimihara, Shodhana, Hridya, Dipana, Pachana properties. In totality ingredient possess Tikta, Katu Rasa, Ushna Virya, Katu Vipaka. Due to these properties it acts as Kaphavatahar and by clearing ‘Srotorodh’ it makes the way for the action of Medhya drugs on target cells

Review on Efficacy of Herbal Antiviral Drugs against COVID-19

Coronavirus disease (CoViD-19) is an infection of the respiratory system caused due to various viruses affects the respiratory pathway, and it can spread from one person to another by coughing, sneezing or physical contact. Commonly include cough, cold, fever are the symptoms. Viral diseases increase worldwide concern, including emerging and chronic viruses. The invention of new anti-viral drugs from plants has implicit in the past. The Coronavirus disease 19 (COVID-19) caused due to severe acute respiratory syndrome, which is a transmittable and pathogenic viral infection. Several traditional medicines of plant origin having antimicrobial and anti-inflammatory properties some have been studied for their anti-viral properties and immune-modulating effects. Herbal drugs are now in massive requirement in the developing countries for primary health care not because of their economical but also for better civilising adequacy, improved compatibility with the human body and significantly fewer side effects. This review gives an overview of some critical traditionally used medicinal herbs with anti-viral properties—the literature regarding the drugs of this group, collected from Ayurveda classics. Research articles are collected from published material and discussed per therapeutic actions. Most of the Herbs are with Katu Rasa (pungent) and Ushna Virya (hot potency). They are indicated in diseases, viz. Kasa (cough), Shwas (asthma), Krumi (worm/ infection). Krumihara property drugs which are correlated with anti-viral action helps to prevent against Novel coronavirus infection.

Standardization of Poly Herbal Cosmetic Formula on Abnormal Pigmentation in Cutaneous Wound Healing – A Preliminary Study

Abnormal pigmentation in cutaneous wound healing has become a major cosmetic issue in the current society. Rising popularity of green labeled cosmetics which are environmentally sustainable with minimum side effects have greater demand in the world cosmetic market. Standardization of herbal formula is essential in order to assess the quality of drugs. Hence, the research study was designed to standardize the selected herbs based on comprehensive literary study on selected Varnaya Dravya (complexion promoting herbs) mentioned in Ayurveda authentic texts and Sri Lankan traditional manuscripts comprising of Terminalia chebula Retz, Terminalia belerica (Gaertn). Roxb, Phyllanthus emblica Linn, Rubia cordifolia Linn, Curcuma longa Trim, and Sesamum indicum Linn. Authentication of herbal ingreedients has been carried out at Bandaranayaka Memorial Ayurveda Research Institute, Nawinna, Sri Lanka. Microscopic identification, Moisture content, pH value, Total ash content and Colouring matter were tested determind through paper chromatography under WHO (2011) guidelines. Microscopic identification revealed that the poly herbal cosmetic formula in powder form contains yellow colour cells, stone cells, group of elongated stone cells, transparent cells, pitted vessels, spiral vessels, vessels filled with red, small fibers, oil globules, starch granules, needle shape crystals, hair and Trichoid. Moreover, moisture content of the formula was 6.3%, pH - 5.92 and total ash value - 4.45%. Determination of colouring matter indicated formula does not contain synthetic dyes. In addition, secondary plant metabolites like phenolic, tannins and saponins were present. Pharmacodynamics potential of the formula showed 25% kashaya (astringent) and tiktta (bitter) rasa (taste) accordingly. Further, 46% and 27% of formula showed ruksha (dryness) and laghu (lightness) guna (properties) along with 83% and 67% indicated ushna virya.
 (hot in potency) and madura (sweet) vipaka respectively. Due to presence of secondary metabolites, the poly herbal formula has anti-bacterial, anti-fungal and anti-oxidant potentials which will be favorable for skin complexion protection from bacteria and fungi. Moreover, Lekhana action gives scraping effect which is important for removing the scar.
 The study suggested that parameters found to be sufficient to evaluate the herbal cosmetic powder and could be used as reference standards and applicability of this formulae should be validated with a preclinical and clinical trials.

Tulasi (Ocimum sanctum Linn.) – A Drug Review

Tulasi ( Ocimum sanctum Linn. belonging family Lamiaceae) is described as a sacred and useful medicinal plant in ancient literature. It is derived from ‘Sanskrit,’ which means the incomparable one. Tulasi leaves have Katu- Kashaya Rasa, as well as Laghu, Ruksha and Tikshna Guna and Ushna Virya . It has proven pharmacological actions such as antioxidant, immune-modulatory, antipyretic, anticancer, chemo-preventive, radio-protective, anti-hypertensive, cardio protective, antimicrobial activity and many more. The present article attempts to collect all necessary information regarding Derivation, Vernacular names, Paryaya , Vargikarana , Rasa Panchaka, Varieties, Karma and Formulations from Samhita and Nighantu. Also Taxonomical position, Pharmacognostical evaluation and pharmacological activities of this plant have also been reviewed from various scientific research articles. The leaf of OS contains 0.7% volatile oil comprising about 71% eugenol and 20% methyl eugenol. Keywords: Tulasi, Ocimum sanctum Linn, Classical view, Pharmacognostical Feature Cite this Article Nidhi Patel, Bharti Umretia. Tulasi (Ocimum sanctum Linn.) – A Drug Review. Research & Reviews: A Journal of Pharmacognosy. 2020; 7(2): 14 – 22p.

THE STUDY OF EFFICACY OF SIMHASYADI KWATHA WITH ERANDA TAILA IN GRIDHRASI

Now a day’s everyone is living a rush full life. Busy life schedule means due to which some of us are suffering from various vataj roga. In Gridhrasi, there is a pain in distribution of sciatic nerve from buttocks to thigh, calf and foot. Many formulae have been prescribed for gridhrasi in Ayurveda. Simhasyadi Kwatha with Eranda taila is prescribed by Bhavprakasha. The ingredients of kwatha are Vasa, Danti, and Aragwadha. These drugs possess ushna virya which acts as vatahara and kaphahara. Eranda taila is the prakshepa in this kwatha acts as potentiator. Gridhrasi affects daily routine of the patients and causes lots of difficulties in movements due to tremendous pain. Hence this study has been done to relieve the patients from their painful illness.

To Study the effect of Pathyadi Choorna in Ajeerna Vyadhi

The fast life style and fast food give rise to the number of diseases, most of them are related to gastro-intestinal tract. Now a day’s most of the people relay on mostly fast food. Some of the people has day-night duties in companies where they mostly prefer fast food because of such life style digestive system undergoes stress. Ayurveda, is the science of life which delts with complete etiology of disease, which we called VYADHI. We dealt with Hetu,Poorva-Roopa, Roopa, Samprapti, Upashay-Anuupshay & Upadrav-Udark. Due to non acceptance of Annapan-Viddhi i.e.Atyambupana1 Vishamashan or following of Virudha Ahar i.e.Sandharan1[mala-mutra veg dharan]Anidra [not complete in timely sleep], it give rise to improper digestion that produces Ama which developes Ajeerna vyadhi 
 Symtoms are Udarshula, Adhman, Atop, Arochak, Shiroruja, Chardi,Glani, Gaurav, Vishtambh, Bhram, Marut Mudhata, Vibhandh, aorva, Gandadakshishopha. Ajirna is having three types mainly Amajeerna,Vishtabadajeerna, Vidagdhajeerna . Pathyadi Choorna1,2 is used as material from the reference of Yog Ratnakar1. We have also follow book like Madhav-Nidan. According to the reference, any person suffering from Ajeerna vyadhi5 with above symptoms can he recovered with the help of Pathyadi Choorna. Haritaki, Pippali and Souvarchala Lavan are the main ingredients which taken in equal quantity, without impurities and converted into powder form i.e. Choorna. This choorna is given to patients of Ajeena Vyadhi. PATHYADI CHOORNA is given 2 gram prati bhojanotter with 50 ml koshna jal .We treated 50 patients with Pathyadi choorna. 
 Observations are made on the basis of data collected from patients from time to time.after detailed observation we came to some conclusion. Contents of Pathyadi Choorna are having Ushna Virya so that it is more effective in Amajeerna. Pathyadi Choorna plays an important role in Ajeerna Vyadhi caused by Agnimandya and in persons having Mandagni. This Kalpa is most useful in types of Ajeerna having chardi than Udgar, Adhman than Atop and Udarshool than Shiroruja. Pathyadi Choorna is very much useful in Ajeena Vyadhi.

Role of takrasevan in agnimandya - a review.

Background: Our health and overall well-being mainly depends on our eating habits, physical activities, sleep patterns etc. Human beings, in order to adjust themselves in the modern era, have been compiled to become fast and mechanical. Due to this they can’t give proper attention to diet and exercise. Due to this Aaharpachan Kriya gets affected leading to Agnimandya (low or decreased digestive power). According to Ayurveda Agnimandya is responsible for almost all diseases. Objectives: Objective is to study importance of Takrasevan in Agnimandya. Material and methods: Ayurvedic / modern texts and literature, research paper. Discussion: Grahani, Atisar, Arsh etc. are the commonest diseases seen in today’s life. These diseases are not life threatening but can cause great distress to patient. Ayurveda gave an amount of treatment modalities; one of them is Takrasevan i. e. consumption of buttermilk. Takra having ushna virya, kashaya rasa, madhur vipak and ruksha guna properties which pacifies Vata, Pitta, Kapha and potentiate the Agni and digests as well as absorbs the food articles and treats the disease in generous way. Conclusion: By this study it can be conclude that Takra (Buttermilk) can use on daily basis as dietary product. As it contains Probiotics which facilitates proper digestion and absorption process, it maintains proper metabolism to keep person free from diseases.

Assessment of Rasapanchaka of Martynia annua Linn root

Dravya is a fundamental and inevitable factor to human life. The likenesses of Dravya and human body from its molecular level made it an essential part of Ayurveda. Five basic principles, namely Rasa (taste), Guna (quality), Vipaka (post digestive taste ), Virya (potency), and Prabhava (unexplained effect) collectively known as Rasapanchaka clarifies pharmacodynamics in Ayurveda. Martynia annua Linn is commonly found in dense clumps on roadsides, degraded moist and dry deciduous forest, waste lands, and throughout India. In folk medicine, decoction of whole plant is administered in patients with pneumonia and cold fever. The leaves of the plant are consumed in times of scarcity and also given in case of epilepsy, and its juice is gargled for sore throat. The fruits are used for the treatment of asthma; the seeds are applied locally for itching and eczema. The roots are boiled with milk and taken as a tonic, and they are made into a poultice and applied in case of snake bite. In tribal pockets of Satpura Plateau in Madhya Pradesh, root paste of M. annua Linn is used in folk medicine to treat cancer and rheumatism, but to accept it in current clinical practice, it is essential to recognize the basic Rasapanchaka of the drug. By knowing the pharmacodynamics, the physician safely prescribes the drug on apt conditions. In this study, Rasapanchaka of M. annua Linn plant root was found with the help of healthy volunteers. Study results revealed Kashaya and Madhura are the Rasa and Anuras of the drug and Ushna and Snigdha are the chief Guna. It is an Ushna Virya drug and its Vipaka is Katu.

Effect of Haritaki (Terminalia Chebula Retz) with Takra in Dandruff

Dandruff is a common scalp disorder affecting almost half of the population. According to Ayurveda, Dandruff may be correlated to Darunaka. Ayurveda classics dealt different procedures and medications to treat the disease Darunaka (dandruff). The present study is based on the reference from Cikitsamanjary by Sreeman Nambootiri, an authentic Ayurveda book. Haritaki mixed with Takra (buttermilk) as Sirolepa (application of paste over the scalp region) is used to reduce Darunaka. Darunaka is a Kapha Vata predominant disease having the symptoms like Kandu (Itching), Kesha Chyuthi (Hair fall), Twak sphutana (Scaling) and Rukshata (Dryness). Haritaki is having Lavanavarjitha Pancha Rasa, Laghu Ruksha Guna, Ushna Virya, Madhura Vipaka and Tridoshahara property (Pharmacological properties). Takram is having Laghu Ruksha Guna, Kasaya, Amla rasa; Ushna Virya and Madhura Vipaka with Kapha Vatahara property. In the clinical study, 30 patients of Darunaka were selected as per inclusion and exclusion criteria. The study was effective in reducing the symptoms of Darunaka.

A clinical study of Shunthyadi churna in the Management of Tamaka shwasa W.S.R. to Bronchial Asthma

In classics Tamaka Shwasa is Pitta Sthana Samudbhava Vhadhi, mainly affected Doshas are Vata and Pitta. In modern science Tamaka Swasa is correlate with bronchil ashtha, Symptoms of Tamaka Swasa is nearly similar to. Bronchial asthma a chronic inflammatory disorder of the airways in which the chronic inflammation causes an associated increase in airway hyperresponsiveness that leads to recurrent episodes of asthmatic exacerbation. Modern science has no permanent cure of Tamaka Swasa, thats why it is necessity to search herbal and herbo-minaral preparations for the treatment of disease. It is safe and effective in asthma. Shunthyadi Churna described in Yogratnakara for the treatment of Shwasa. Aim: Role of Shunthyadi Churna in treatment of Tamaka Shwasa. Materials and Methods: Total 23 patients of Tamaka Shwasa age group of 18 to 60 years fulfilling the inclusion criteria were selected for trial. Disscussion: Properties having Shuthyadi Churna is Tikta Katu Rasa, Laghu and Tikna Guna (light and penetrating properties), Ushna Virya (hot potency) and Vatakaphagna (decrease Vata and Kapha Dosha). Shuthyadi Churna is effective in break down the Samprapti of Tamaka Swasa and effective remedy for the patient of bronchial asthma.

UNDERSTANDING THE PHARMACOKINETICS OF MAMAJJAKA (ENICOSTEMMA LITTORALE BLUME) AS A DIETARY SUPPLEMENT IN DIABETES MELLITUS.

Enicostemma littorale Blume, also known as Mamajjaka in Sanskrit, Indian gentian in English and “Kadavinay” in local language, is a perennial herb of Gentianaceae family. The plant parts like leaves and roots are used since ages in various parts of India for treating diabetes. It is widely used in Solapur and Osmanabad districts of Maharashtra, in the form of “leaf pickle” as a dietary supplement in diabetic patient. Acharya Priyavat Sharma has described it as useful in madhumeha. Mamajjaka has a predominance of Tikta rasa, Ushna virya, Katu vipaka, Laghu-Ruksha guna and Vayu-Aakash mahabhuta. It’s an easily available and economically important herb. Different constituents of Mamajjaka, like Swertiamarin, Flavonoids, Saponins, triterpenoids, alkaloids, catechins, sterols, phenolic acids and xanthones, have been reported for possessing hypoglycemic properties. In-vivo, anti-hyperglycemic effect of Mamajjaka has been established, through enhancing glucose-induced insulin release, reducing the glycosylated hemoglobin and by inhibiting the action of glucose-6-phosphate in liver. As, all previous studies have established the significant potentials of Mamajjaka both in Type-1 and Type-2 diabetes, in this study we have reviewed the pharmaco-kinetics of Mamajjaka, keeping in mind the scientific basis of traditional use of Mamajjaka mainly as diet in diabetes. We have established the role of panchabhautic constitution of Mamajjaka as a dietary supplement for the diabetic patients. We have concluded that Mamajjaka, being cost-effective and easily available medicinal herb possessing hypoglycemic properties, can be used as an excellent vegetable in diabetic patients as a dietary supplement.

THERAPEUTIC IMPORTANCE OF HARIDRADI GANA IN THE MANAGEMENT OF MADHUMEHA W.S.R TO DIABETES MELLITUS

Abstract:
 Background: Haridradi gana is a specific classification described in Astanghrudaya which contains five such medicinal herbs that are mainly recommended in prameha
 .Objectives: To study five herbs of haridradi gana for their Antidiabetic potential as per Ayurvedic perspective. To study the Rasa,guna,virya,vipaka of haridradi gana.
 Methodology: Haridradi gana is the 17th number of gana in the gana’s of Ashtang hruday. This gana includes total 5 number medicinal herbs these are Haridra,Daruharidra,Yashtimadhu,Prushaniparni,Indrayav and analysis of these five drugs regarding rasa,guna,virya,vipaka.
 Result: –Maximum contents of haridradi gana having 70% of tikta pradhan katu rasa, 70% ushna virya and 80% katu vipak,60% of laghu-ruksha guna.. Tikta rasa has shoshak property, tikta rasa absorbs kleda-meda-vasa-majja-lasika-puya-sweda-mutra-purisha-pitta and kapha.it also rectifies agni leads to proper utilization of insulin in the periphery leads to reduction in insulin resistance. ushana virya causes stroto shodhana it leads to absorption of circulating free glucose by cells and reduces hyperglycemia.Laghu-ruksha guna destroys accumulation of kapha and meda.and By the side katu vipaka helps to remove sneha, sweda, kleda, and mala from body.
 Conclusion:The present study reveals that the herbs included in haridradi gana having dominantly tikta-katu rasa,ushana virya,katu vipaka,laghu-ruksha guna significantly plays role as an anti-diabetic.