The current study is modelled to evaluate numerous flow applications in applied sciences espeically in nuclear reacting cooling, geothermal reservoirs, chemical engineering and thermal oil recovery. The present research investigates the magnetohydrodynamic transport of non-Newtonian Casson Nano fluid past due to stretching permeable cylinder by employing Buongiorno's mathematical model. Unlike the frequently used constant temperature and concentration boundary conditions, the present study employed convective boundary conditions. The influences of important sundary parameters like an inclination of magnetic field, joule heating, viscous dissipation, thermophoresis, Brownian motion, Arrhenius activation energy, and chemical reaction are taken into account. The physical flow phenomenon is modelled and after that transformed into a non-dimensional form by incorporating suitable similarity transforms. For solution purpose, Runge-Kutta-Fehlberg fourth-fifth order (RKF45) numerical integrating procedure along with shooting algorithm is adopted. Impacts of several emerging parameters on the velocity distribution, temperature distribution, and concentration distribution, coefficient of skin friction, Sherwood number, and Nusselt number are clarified via graphical and tabular results. It seems to establish that with the rise of chemical reaction parameter chemical reaction parameter the nanoparticles concentration distributions decline while the contrasting trend is perceived for activation energy parameter.