Tube System Research Articles

Using APRIS for QA/QC of Newly Fabricated Heat Exchangers

Acoustic Pulse Reflectometry (APR) has been applied extensively to tubular systems in research laboratories, for purposes of measuring input impedance, bore reconstruction, and fault detection. Industrial applications have been mentioned in the literature, though they have not been widely implemented. Academic APR systems are extremely bulky, often employing sophisticated set up, which limits their industrial use severely. Furthermore, leak detection methods described in the literature are based on indirect methods, by carrying out bore reconstruction and finding discrepancies between the expected and reconstructed bore. Here, we describe an APR system which is named APRIS designed specifically for detecting faults commonly found in industrial tube systems such as heat exchangers, condensers and boilers leaks, increase in internal diameter caused by wall thinning, and constrictions by blockages or deposits or scales. The system employs extremely hardware setup, making it extremely portable, but creating a large degree of overlap between forward and backward propagating waves in the system. A series of patented algorithmic innovations enable the system to perform the wave separation mathematically, and then identify the above faults automatically, with a measurement time on the order of 10 seconds per tube.

NUMERICAL INVESTIGATION OF DYNAMIC RESPONSE CHARACTERISTIC OF DAMPED BRACED TUBE SYSTEM WITH DIFFERENT DAMPED SLIT COMFIGURATION

This paper investigated the dynamic response characteristic with focus on damped slit configuration of damped braced tube systems with oil dampers. According to the results, 1) damped braced tube system has over 10% 1st to 3rd damping ratio, 2) while the displacement and acceleration responses are simultaneously reduced up to maximized 1st mode damping ratio, the acceleration reduction effect may be getting worse after the peak, 3) while uniform damper distribution contributes to better damping performance, centralized damper distribution contributes to better period reduction.

Cell-Mimic Directional Cargo Transportation in a Visible-Light-Activated Colloidal Motor/Lipid Tube System.

Active tether and transportation of cargoes on cytoskeletal highway enabled by molecular motors is key for accurate delivery of vesicles and organelles in the complex intracellular environment. Here, a hybrid system composed of colloidal motors and self-assembled lipid tubes is designed to mimic the subcellular traffic system in living cells. The colloidal motors, composed of gold-coated hematite, display light-activated self-propulsion tunable by the light intensity and the concentration of hydrogen peroxide fuel. Importantly, the motors show light-switchable binding with lipid cargoes and attachment to the lipid tubes, whereby the latter act as the motor highways. Upon assembly, the colloidal motor/lipid tube system demonstrates directional delivery of lipid vesicles, emulating intracellular transportation. The assembly and function of the hybrid system are rationalized by a cooperative action of light-triggered electrophoretic and hydrodynamic effects, supported by finite element analysis. A synthetic analog of the biological protein motor/cytoskeletal filament system is realized for the manipulation and delivery of different matter at the microscale, which is expected to be a promising platform for various applications in materials science, nanotechnology, microfluidics, and synthetic biology.

Comparison between mainstream (Capnostat 5) and a low-flow sidestream capnometer (Capnostream) in mechanically ventilated, sevoflurane-anesthetized rabbits using a Bain coaxial delivery system

ObjectiveTo evaluate agreement between end-tidal carbon dioxide (Pe′CO2) and PaCO2 with sidestream and mainstream capnometers in mechanically ventilated anesthetized rabbits, with two ventilatory strategies. Study designProspective experimental study. AnimalsA total of 10 New Zealand White rabbits weighing 3.6 ± 0.3 kg (mean ± standard deviation). MethodsRabbits anesthetized with sevoflurane were intubated with an uncuffed endotracheal tube (3.0 mm internal diameter) and adequate seal. For Pe′CO2, the sidestream capnometer sampling adapter or the mainstream capnometer was placed between the endotracheal tube and Bain breathing system (1.5 L minute–1 oxygen). PaCO2 was obtained from arterial blood collected every 5 minutes. A time-cycled ventilator delivered an inspiratory time of 1 second and 12 or 20 breaths minute–1. Peak inspiratory pressure was initially set to achieve Pe′CO2 normocapnia of 35–45 mmHg (4.6–6.0 kPa). A total of five paired Pe′CO2 and PaCO2 measurements were obtained with each ventilation mode for each capnometer. Anesthetic episodes were separated by 7 days. Agreement was assessed using Bland-Altman analysis and linear mixed models; p < 0.05. ResultsThere were 90 and 83 pairs for the mainstream and sidestream capnometers, respectively. The mainstream capnometer underestimated PaCO2 by 12.6 ± 2.9 mmHg (proportional bias 0.44 ± 0.06 mmHg per 1 mmHg PaCO2 increase). With the sidestream capnometer, ventilation mode had a significant effect on Pe′CO2. At 12 breaths minute–1, Pe′CO2 underestimated PaCO2 by 23.9 ± 8.2 mmHg (proportional bias: 0.81 ± 0.18 mmHg per 1 mmHg PaCO2 increase). At 20 breaths minute–1, Pe′CO2 underestimated PaCO2 by 38.8 ± 5.0 mmHg (proportional bias 1.13 ± 0.10 mmHg per 1 mmHg PaCO2 increase). Conclusions and clinical relevanceBoth capnometers underestimated PaCO2. The sidestream capnometer underestimated PaCO2 more than the mainstream capnometer, and was affected by ventilation mode.

Seismic response analysis of high-rise frame-core tube building on fluid-saturated soil considering soil-pile-structure interaction

This paper proposed a three-dimensional (3D) refined finite element method (FEM) to determine seismic responses of the high-rise buildings resting on fluid-saturated soil considering the soil-pile-structure interaction (SPSI) and the dynamic characteristics of two-phase media, using a user-defined element with ABAQUS. The theory and method to develop the FEM were introduced in detail, including the user-defined element, material constitutive models, boundary conditions, earthquake input methods, specific implementation procedures, and verifications. Then, the FEM was adopted to investigate the seismic responses of a 51-story high-rise building with a frame-core tube system subjected to six earthquake records. Discussions were conducted on the acceleration, displacements, inter-story drifts, story shear force, and damage behavior to interpret the seismic characteristics of the superstructure. A fixed-base model was also considered to reveal the SPSI effect under the same conditions. The results demonstrate that the SPSI lightens acceleration and total story shear force but amplifies displacements, inter-story drifts, and column shear force. Without regard to the SPSI, no apparent change appears for the damage of floor plates, whereas the core tube suffers more severe damage than under the SPSI conditions. For high-rise buildings, the SPSI does not always provide conservative seismic performance evaluations. It is of fundamental importance to include the SPSI effect during the performance-based seismic design of high-rise buildings for comprehensive understanding. The proposed FEM can also be access to seismic SSI analysis for other types of structures in the saturated field.

Successful Ex Vivo Telomere Elongation with Exg-001 in a Patient with a Dyskeratosis Congenita

We report a first-in-human gene therapy strategy to extend telomere length in patients with telomere biology disorders. Patients with telomere biology disorders, including dyskeratosis congenita, have extremely short telomeres leading to premature cellular senescence and increased risk of bone marrow failure. Zinc Finger and SCAN Domain Containing 4 (ZSCAN4) is a protein that regulates telomere elongation, enhances genome stability, and is expressed transiently in preimplantation embryos, germ cells during meiosis, embryonic stem cells, and rare adult tissue stem cells. EXG-001 is a non-integrating temperature-sensitive non-transmissible Sendai virus vector encoding for human ZSCAN4. We demonstrated that the transient exposure to ZSCAN4 via EXG-001 extended telomeres of primary fibroblast cells derived from dyskeratosis congenita patients as well as healthy human CD34+ cells. However, we did not know whether EXG-001 can extend short telomeres of CD34+ cells of dyskeratosis congenita patients. We translated this work in a first-in-human clinical trial (NCT04211714), in which autologous CD34+ hematopoietic stem cells (HSC) were collected by pheresis from an adult subject with dyskeratosis congenita over two days after mobilization with plerixafor and filgrastim with IRB approval and consent. 2.8x106 CD34/kg were collected and treated with EXG-001 ex vivo in a functionally closed tubing system using the CliniMACS Prodigy (Miltenyi Biotec). EXG-001 treatment increased telomere length of the CD34+ cells of study subject by 1.24-fold, bringing them into the healthy normal control range of CD34+ cell telomere length (Figure 1A). To address the concern of effects on terminal colony forming unit studies were performed and demonstrated maintenance of normal differentiation potential after treatment (Figure 1B; EXG34217). 0.85x106 CD34/kg autologous treated HSC (EXG34217) were reinfused into the subject in February 2022 without conditioning regimen and further in vivo studies are in progress. This novel approach is genotype and mutation independent and uses modified autologous stem cells in the absence of conditioning regimen or immunosuppression which is highly desirable in this radiation and chemotherapy sensitive population. These data support further investigation and translation of telomere elongation via ZSCAN4 exposure by EXG-001 in patients with telomere biology disorders as a potential therapeutic intervention for the prevention or treatment of bone marrow failure. Figure 1View largeDownload PPTFigure 1View largeDownload PPT Close modal

A coupled combustion and hydrodynamic model for the prediction of waterwall tube overheating of supercritical boiler

Tube overheating is the leading cause of boiler tube failures that had led to tremendous replacement and maintenance costs. Boiler tube temperature is simultaneously affected by the heating effect of hot combustion gas in the furnace and the cooling effect of steam flow in boiler tubes. Thus, prediction of tube temperature needs to include the simulations of both the gas and steam flows of the boiler in the model. To compromise the significant scale difference between the boiler furnace and tubes, a coupled model that integrates a three-dimensional (3D) CFD model describing the gas flow and combustion processes in the furnace with a one-dimensional (1D) hydrodynamic model describing the steam flow in the boiler waterwall tubes was developed in this paper. The 3D CFD and 1D hydrodynamic models are coupled by iterative data exchange of boiler heat flux and steam temperature between the two models. In this way, this coupled model can incorporate all the key parameters that strongly affect the waterwall tube temperature, including the distributions of boiler heat flux, steam temperature and the convective heat transfer coefficient of steam flow in boiler tubes. In particular, the critical effects of steam maldistribution caused by both the structure of tube network system and uneven heat absorption of parallel tubes on tube temperature can be resolved by this model. This coupled model provides the capability to predict the detailed distribution of waterwall tube temperature and locate the areas of tube overheating under different boiler operating parameters. This coupled model was employed to predict the tube temperature distribution of the spiral waterwall of a 350 MW supercritical boiler. The predicted results show that the areas having higher risk of tube overheating are located near the outlet of spiral waterwall tubes where the steam temperature is the highest and on the wall areas where the local wall heat flux is the highest. The results strengthen the necessity of incorporating both the gas and steam sides of boiler into the model for accurate prediction of waterwall tube temperature.

Reactive uptake coefficients for multiphase reactions determined by a dynamic chamber system

Abstract. Dynamic flow-through chambers are frequently used to measure gas exchange rates between the atmosphere and biosphere on the Earth's surface such as vegetation and soils. Here, we explore the performance of a dynamic chamber system in determining the uptake coefficient γ of exemplary gases (O3 and SO2) on bulk solid-phase samples. After characterization of the dynamic chamber system, the derived γ is compared with that determined from a coated-wall flow tube system. Our results show that the dynamic chamber system and the flow tube method show a good agreement for γin the range of 10−8 to 10−3. The dynamic chamber technique can be used for liquid samples and real atmospheric aerosol samples without complicated coating procedures, which complements the existing techniques in atmospheric kinetic studies.

P036 Rapid oscillatory ventilation seen during positive airway pressure titration studies: A case series

Abstract We have observed a phenomenon in some patients undergoing positive airway pressure implement/titration studies in our sleep lab, characterised by periods of extremely high respiratory rates of up to 80 breaths/min which appear to be device triggered. These episodes occur during periods of central apnoea and last up to 1.5-2.0 minutes. A possible related phenomenon has been reported in a case series of 4 patients published in the Journal of Clinical Sleep Medicine in 2018 (Gupta et al), however this was using a different CPAP device and respiratory rates were significantly lower than what we have observed. Apart from this, there are no reports in the literature that are consistent with the observations we have made in our lab. Correspondence from the device vendor have suggested that the episodes are due to a rare state in the motor control system which maintains correct pressure in the mask circuit and may have been influenced by our lab not using the vendor’s proprietary heated tubing system. In addition, the incidence rate of this is said to be extremely low at 0.00087%, although our lab has already observed at least 5 cases of this in the 6 months from August 2021 to February 2022. Our objective is to present a case series to inform the broader sleep community of our unique observations.

Comparative Study of Tube in Tube System and Bundled Tube System for High Rise Building

In India, reinforced concrete frames are the most popular kind of construction. High-rise buildings have grown extremely popular in India as a result of the country rapid urbanization, which has led to an increase in land prices and the need for agricultural land. High-rise buildings must support loads other than only gravity, Lateral forces as well, since many significant Indian cities are located in seismically active areas, buildings must be strengthened. It is crucial for lateral forces. The purpose of this study is to examine the efficient, cost-effective, and safe structure between the Bundled tube system and the Tube in Tube system, The Tube in Tube and Bundled Tube ETABS versions, For analysis, the G+30 stories. These multiple-story structures can be converted into tall buildings that use less space but have more floor space land area. Tubular buildings have become more prevalent in recent years, becoming a typical component of towering buildings. structural tubes are especially appropriate for all tall constructions. In the planning of in towering buildings, lateral loads are a major factor. Wind and earthquake loads are examples of loads. seismological analysis is utilizing the equivalent static approach. The simulation Etabs software is used for analysis. Bare frame, Tube in Tube and Bundle tube Structure is Modelled structures are used. Compared and interpreted for three different models.

Daily timings of sap production in sugar maple in Quebec, Canada.

Global warming is affecting plant phenology, with potential consequences on the dynamics of growth reactivation of sugar maple and the timings of maple syrup production. In this study, we assess the temperatures inducing the daily reactivation or cessation of sap production. We selected 19 sugarbushes across Quebec, Canada, using a tapping method associated with the tubing system, we recorded the daily timings of onset and ending of sap production during winter and spring 2018, and we associated the hourly temperatures at each site. Sap production occurred from mid-February to the end of April, starting on average between 10 and 11 AM, and ending from 6 to 8 PM. We observed a seasonal pattern in the onset and ending of sap production during spring, with the onset showing a greater change than the ending. Onset and ending of sap production occurred mostly under temperatures ranging between -2 and 2°C. The production of sap in maple is closely related to circadian freeze-thaw cycles and occurs under nighttime and daytime temperatures fluctuating below and above 0°C. The daily lengthening of the duration of sap production mirrors the changes in the timings of freeze and thaw events and can be explained by the physical properties of the water and the physiological processes occurring during growth reactivation. The ongoing warming will result in earlier and warmer springs, which may anticipate the cycles of freeze and thaw and advance sap production in sugar maple.

Thermal Analysis and Static Lubrication Performance Study of Liquid Metal Journal Bearing

The temperature distribution of liquid metal journal bearing system in X-ray tube of medical CT machine was simulated by using simulation software, and the working temperature of the herringbone groove liquid metal journal bearing was initially determined. On this basis, the lubricating properties of the liquid metal lubricant were analyzed. The lubrication model of herringbone groove liquid metal journal bearing with Galinstan liquid metal as lubricant was established, and the influence of herringbone groove structure parameters on the static lubrication performance of liquid metal journal bearings was analyzed. The results show that the Galinstan liquid metal has good high temperature stability and can act as a reliable lubricant in the high temperature working environment of the medical CT machine X-ray tube.

An integrated instrument of a tandem quadrupole mass spectrometer for cluster reaction and soft-landing deposition.

We have developed an integrated instrument system of a multiple-ion laminar flow tube (MIFT) reactor combined with a tandem quadrupole mass spectrometer (TQMS) and soft-landing deposition (SD) apparatus. A customized water-cooling magnetron sputtering (MagS) source is designed, by which we are able to attain a highly efficient preparation of metal clusters of 1-30 atoms with tunable size distributions. Following the MagS source, a laminar flow tube reactor is designed, allowing for sufficient gas-collision reactions of the as-prepared metal clusters, which is advantageous for probing magic clusters and minimizing wall effects when probing the reaction dynamics of such clusters. The customized TQMS analyzer involves a conical octupole, two linear octupoles, a quadruple ion deflector, and a 19mm quadruple mass analyzer, allowing to decrease the pressure stepwise (from ∼5 to ∼10-9 Torr), thus ensuring high sensitivity and high resolution of the mass spectrometry analysis. In addition, we have designed a dual SDapparatus for the mass-selected deposition of clusters and their reaction products. For the whole system, abbreviated as MagS-MIFT-TQMS-SD, we have performed a detailed ions-fly simulation and quantitatively estimated the ions transfer efficiency under vacuum conditions determined by real experiments. Taking these advantages, well-resolved Pbn +, Agn +, and Nbn + clusters have been produced, allowing for meticulous studies of cluster reactions under sufficient gas-phase collisions free of electric field trapping. Also, we have tested the efficiency of the dual SD.

Improving efficiency and renewables utilization by hybrid heating plants for industrial buildings

In this paper, a typical industrial building was modelled using a dynamic simulation software in three very different climatic zones in Italy. On the basis of the thermal loads, a hybrid condensing radiant tubes heating system was modelled. The radiant tubes system was coupled to an air heating system with terminals placed in the building fed by two heat sources: one deriving from the condensation of the exhausted of the radiant tubes, and the other by a heat pump with external air heat source. The energy performance of the hybrid heating system was evaluated by optimizing the nominal power of the heat pump, the bivalent temperature in alternative bivalent operation (the system gives priority to the heat pump, which switches off when the outside air temperature drops below the bivalent temperature and the radiant tubes turn on), and the peak power of the photovoltaic system on the roof of the building. This analysis was performed taking into account the variation in heat pump performance with the outside air temperature. The optimal configuration of the hybrid heating system (minimizing the annual amount of total non-renewable primary energy and maximizing the non-renewable primary energy ratio) was then compared to some more traditional heating systems for industrial buildings to evaluate the energy advantages of this innovative solution.

Comparison between use courier transport with pneumatic tube system on the results of routine hematology test, Prothrombin Time (PPT), Activated Partial Thromboplastin Time (APTT), and potassium

Pneumatic tube system (PTS) is a transport medium that is widely used in hospitals. The samples transported via PTS would get vibrations due to changing air velocity and pressure. This unstable pressure could cause pre-analytic errors in laboratory measurements. It happened because it damages erythrocytes and lymphocytes and causes haemolysis. It has been demonstrated that these changes can alter the quality of samples and induce haemolysis by leading primarily to increase in lactate dehydrogenase (LDH) concentrations, and potassium concentration. Haemolysis is dined as the release of intracellular components of erythrocytes and other blood cells into the extracellular space of blood. It can also affect the results of in vitro platelet function test. Incorrect test results can affect the diagnosis and the treatment for patients Every hospital that uses PTS are advised to validate and investigate that PTS has the possibility of haemolysis and impacts laboratory results of blood specimens. The purpose of the study was to validate and know comparison between use courier transport with using PTS on the results of routine haematology tests, PPT, APTT, and potassium. This research was experimental research by using posttest without control. The research used statistical test which was paired t-test. The research was conducted at the Integrated Clinical Laboratory Installation of the Gadjah Mada University Academic Hospital in August – October 2020 with 30 preoperative patients. Data were analysed with Prism GraphPad 8 software. There was no significant difference between WBC, RBC, Hb, HCT, MCV, MCH, MCHC, PPT, and APTT. Moreover, there was a significant difference between the results of PLT and potassium in the samples transported via PTS and delivered by courier transport.

Analysis of stagger effects on Busemann supersonic biplane airfoil in shock tube tests by point diffraction interferometer method

The Busemann biplane concept is proposed for low-boom low-drag supersonic aircraft. Studies on the supersonic biplane have been focused on supersonic flow, whereas the understanding of transonic aerodynamic characteristics is essential for aircraft design. Significantly, the complicated flow field with a shock and boundary layer interaction between Busemann biplane elements in transonic flow remains unclear. In the present study, the transonic aerodynamic characteristics of the two-dimensional Busemann biplane are investigated by shock tube tests and numerical simulations, focusing on the flow field between the biplane elements. In addition, the stagger effects, which change the relative position of the lower and upper elements in the freestream direction to avoid the choked flow between the biplane elements, are also analyzed. A shock tube system creates a test flow at Mach numbers of 0.6 to 0.8, and the Reynolds number is set at 2.85 × 105. The Point Diffraction Interferometer (PDI) method is applied to determine the density distribution around the model and the pressure coefficient on the surfaces of the biplane elements. Symmetrical density distribution is confirmed in the Busemann biplane (the baseline model, or the biplane with no stagger). A normal shock wave is generated between the biplane elements. When the Mach number increases, the normal shock wave moves downstream. The normal shock position is quantitatively stable with small fluctuation amplitudes. The fringes are strongly curved near the surfaces of the biplane elements due to the flow separation near the airfoil surfaces. When the Mach number increases, the separation area increases. When the Mach number increases, the peak value of the pressure coefficient on the surfaces of the biplane elements increases. On the other hand, the normal shock wave between the biplane elements is eliminated in the staggered models. The changes in density distribution between the biplane elements are minor compared to the case of the baseline model, which indicates that the stagger reduces the choked flow between the biplane elements. The peak value of the pressure coefficient on the wing surface increases when the stagger value increases. The stagger effects on reducing the total drag coefficient of the biplane models are confirmed.

Thin layer chromatography/desorption flame-induced atmospheric pressure chemical ionization/mass spectrometry for the analysis of volatile and semi-volatile mixtures.

A micro-sized oxyacetylene flame was generated using a small concentric tube system. Hot gas flow and primary reactive species from the micro-flame were directed toward a developed TLC gel plate to thermally desorb and ionize analytes on the gel surface. The resulting analyte ions subsequently entered the MS inlet for detection. A 1-1.5-mm-wide light-brown line was observed on the TLC plate after the desorption FAPCI/MS (DFAPCI/MS) analysis, revealing that the gel surface withstood a high temperature from the impact of the micro-flame. Volatile and semi-volatile chemical compounds, including amine and amide standards, drugs, and aromatherapy oils, were successfully desorbed, ionized, and detected using this TLC/DFAPCI/MS. The limit of detection of TLC-DFAPCI/MS was determined to be 5ng/spot for dibenzylamine and ethenzamide. TLC/DFAPCI/MS is one of the simplest TLC-MS interfaces showing the advantages such as low costs and an easy set up. The technique is useful for characterizing thermally stable volatile and semi-volatile compounds in a mixture.

Symptom Localization May Differentiate Subtypes of Eustachian Tube Dysfunction.

To evaluate the predictive ability of symptom self-localization to distinguish obstructive eustachian tube dysfunction from non-obstructive salpingitis. Adult (age ≥18 years) patients with a primary complaint of aural discomfort who underwent diagnostic nasal endoscopy and tympanometry at a tertiary academic center were enrolled. Symptoms were self-localized by using a single finger on the affected side. All patients completed the 7-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) and underwent scoring of eustachian tube inflammation using the Endoscopic Evaluation of the Eustachian Tube (3ET) system. Seventy-three patients were included in the study. Symptoms were localized to the external auditory canal (EAC) in 28 (38.4%), to the infratemporal fossa (ITF) below the lobule in 37 (50.7%), and to the preauricular region in 8 (11.0%). Demographics and medical history were similar between groups. The EAC group had significantly more negative tympanometric peak pressure (TPP) (median, -92.0 daPa; IQR, 95.5) and higher 3ET scores. In contrast, the ITF group had normal TPP (median, -2.0 daPa; IQR, 7.0) and higher 3ET scores. The preauricular group was more likely to have temporomandibular joint or pterygoid muscle pain. ETDQ-7 scores did not differ significantly between groups. Symptom localization is associated with specific objective findings in the evaluation of aural discomfort. Patients with pain localizing to the ITF are more likely to have findings of eustachian tube salpingitis without obstruction whereas patients with symptoms deep in the EAC are more likely to have findings consistent with obstructive eustachian tube dysfunction. 3 Laryngoscope, 133:1818-1823, 2023.

Radiation Input/Output System in a Ten-Barrel W-Band Gyrotron-Type Traveling-Wave Tube with Helically Corrugated Waveguides

Radiation Input/Output System in a Ten-Barrel W-Band Gyrotron-Type Traveling-Wave Tube with Helically Corrugated Waveguides

The effect of thermochemical sulfate reduction of n-pentane and condensate on the chemical and isotopic compositions of gases: Implications for the organic reactant and reaction extent

Evaluating the composition of organic reactants initially involved in thermochemical sulfate reduction (TSR) reaction and better understanding the chemical and isotopic compositions of gases are helpful to minimize the risks involved in exploration of natural sour gas reservoirs. Variations in the chemical and carbon isotopic compositions of the gas produced during high pressure (50Mpa), isothermal (360 °C) hydro-pyrolysis experiments of the TSR reaction and thermal cracking involving n-pentane (n-C5) and condensate were investigated using a high-pressure gold tube system. The results show that the yields of CH4, CO2 and H2S increased with reaction time, and that the yields of C2–C4 firstly increased and then decreased. The δ13C value of alkane gases increased with reaction time. The δ13C value of CO2 produced from the TSR reaction involving n-C5 became less negative. The yields of alkane gas, CO2 and H2S from the TSR reaction of n-C5 were up to two times higher than that those from the TSR reaction of condensate. This indicates that lighter liquid hydrocarbons with higher hydrogen content produce more hydrocarbon and non-hydrocarbon gases. The relationship between the dryness, δ13C values of alkane gases and sourness could help to estimate whether the organic reactant was liquid or gaseous hydrocarbons. The value of ln(C2/C3) at the early stage of TSR reaction can be used to roughly estimate the composition of the liquid hydrocarbons involved in the TSR reaction. Our analysis also shows that the value of ln(C2/C3) firstly increased and then decreased with increasing gas dryness during the TSR reaction, which could be an effective index to assess the TSR reaction extent and provide new clues for identifying gas origin. The δ13C values of methane and ethane produced in the TSR reaction involving n-C5 reversed to δ13C1 > δ13C2 during the 48–60h period, which could be related to the oxidation of alkanes by HSO4−. This could help explain the δ13C1 > δ13C2 in TSR influenced gas reservoirs with low H2S content.