A voltage-programmed pixel circuit based on low-temperature poly-silicon (LTPS) thin-film transistors (TFTs) is presented for active-matrix organic light-emitting diode (AMOLED) displays. The circuit consists of six p-type transistors and one capacitor (6T1C). During the extraction stage, the circuit extracts the driving TFT’s threshold voltage and the power supply voltage. During the data input stage, the circuit generates a charging voltage, which is associated with the driving TFT’s mobility and the OLED’s threshold voltage. Consequently, the pixel circuit, using only one capacitor, compensates not only for the TFT’s electrical characteristics variations, i.e., the threshold voltage variation and mobility variation, but also for the power supply voltage drop and the OLED degradation. The circuit simulation results reveal that the OLED current error rates (CERs) are lower than 5.09% when the threshold voltage varies by ±0.5V, lower than 3.61% when the mobility varies by ±30%, and lower than 9.16% when the voltage drop varies by −0.5V in the data voltage range.