Purpose. The purpose of the article is the analysis of the recreational potential of the Cherkasy region, the characteristics of the activities of institutions that specialize in medical and health tourism, and the determination of their spatial structure. Methods. General scientific methods, namely analysis, synthesis and generalization, were used for the research. The sources of information for the research are the scientific works of specialists whose research is related to medical and health tourism, as well as data on recreational facilities of the Cherkasy region, posted on the Internet. Results. Prerequisites for development and natural healing factors underlying the operation of recreation facilities in Cherkasy region have been established. Medical and health facilities of Cherkasy Region are mainly represented by sanatoriums, preventive sanatoriums and recreation centers. It was found that sanatoriums and health facilities are located unevenly on the territory of the region and are concentrated mainly near the coast of the Kremenchug Reservoir. The existing material and technical base of medical and health facilities of the Cherkasy region was studied and the idea of their range of services was expanded. Scientific novelty. The activities of the most famous medical and health facilities of the Cherkasy region were analyzed. The spatial structure was clarified and the main physico-chemical and therapeutic properties of mineral waters used by recreation facilities for the treatment and prevention of various diseases were revealed. Proposals have been made to expand the range of services of institutions. The practical significance. The results of the research highlighted in the article can be used by employees of recreation facilities of Cherkasy region and other medical and health centers of Ukraine, as well as within the educational process by students of specialties 242 "Tourism", 014.07 "Secondary education (Geography)" and others in order to expand their understanding about the resource and recreational potential of the Cherkasy region.