Introduction: Patellofemoral pain syndrome is one of the most common musculoskeletal disorders of the knee area. Previous studies have pointed to the positive effects of exercise. Therefore, it is very important to check the types of exercise protocols for the treatment of this condition. The purpose of the present study was to investigate the scientific framework of research related to the application of various exercise protocols on patellofemoral pain syndrome, as well as to make a favorable summary and provide more appropriate information from previous researches. In this review study, the search for articles in Persian and English languages in 2022 (until November) was carried out on WOS, Magiran, Scopus, Google Scholar, PubMed, and Springer databases. The keywords of patellofemoral pain syndrome, knee and knee rehabilitation were used to extract articles. 100 relevant articles were selected based on inclusion and exclusion criteria. After reviewing 100 articles, the number of 53 article titles that were close to the research title met the criteria for inclusion in the present study. After re-examining the articles, 25 articles were selected with the aim of examining the exercise protocol on patellofemoral pain.
 Conclusion: It seems that sports exercises with the aim of strengthening the muscles around the knee joint are effective in the recovery process and reducing the pain of people suffering from patellofemoral syndrome.
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