Spatial Resolution Images Research Articles

Deep Learning Approach to Improve Spatial Resolution of GOES-17 Wildfire Boundaries Using VIIRS Satellite Data

The rising severity and frequency of wildfires in recent years in the United States have raised numerous concerns regarding the improvement in wildfire emergency response management and decision-making systems, which require operational high temporal and spatial resolution monitoring capabilities. Satellites are one of the tools that can be used for wildfire monitoring. However, none of the currently available satellite systems provide both high temporal and spatial resolution. For example, GOES-17 geostationary satellite fire products have high temporal (1–5 min) but low spatial resolution (≥2 km), and VIIRS polar orbiter satellite fire products have low temporal (~12 h) but high spatial resolution (375 m). This work aims to leverage currently available satellite data sources, such as GOES and VIIRS, along with deep learning (DL) advances to achieve an operational high-resolution, both spatially and temporarily, wildfire monitoring tool. Specifically, this study considers the problem of increasing the spatial resolution of high temporal but low spatial resolution GOES-17 data products using low temporal but high spatial resolution VIIRS data products. The main idea is using an Autoencoder DL model to learn how to map GOES-17 geostationary low spatial resolution satellite images to VIIRS polar orbiter high spatial resolution satellite images. In this context, several loss functions and DL architectures are implemented and tested to predict both the fire area and the corresponding brightness temperature. These models are trained and tested on wildfire sites from 2019 to 2021 in the western U.S. The results indicate that DL models can improve the spatial resolution of GOES-17 images, leading to images that mimic the spatial resolution of VIIRS images. Combined with GOES-17 higher temporal resolution, the DL model can provide high-resolution near-real-time wildfire monitoring capability as well as semi-continuous wildfire progression maps.

Automatic MTF Conversion between Different Characteristics Caused by Imaging Devices.

Depending on various design conditions, including optics and circuit design, the image-forming characteristics of the modulated transfer function (MTF), which affect the spatial resolution of a digital image, may vary among image channels within or between imaging devices. In this study, we propose a method for automatically converting the MTF to the target MTF, focusing on adjusting the MTF characteristics that affect the signals of different image channels within and between different image devices. The experimental results of MTF conversion using the proposed method for multiple image channels with different MTF characteristics indicated that the proposed method could produce sharper images by moving the source MTF of each channel closer to a target MTF with a higher MTF value. This study is expected to contribute to technological advancements in various imaging devices as follows: (1) Even if the imaging characteristics of the hardware are unknown, the MTF can be converted to the target MTF using the image after it is captured. (2) As any MTF can be converted into a target, image simulation for conversion to a different MTF is possible. (3) It is possible to generate high-definition images, thereby meeting the requirements of various industrial and research fields in which high-definition images are required.

Thin slice photon-counting CT coronary angiography compared to conventional CT: Objective image quality and clinical radiation dose assessment.

Photon-counting CT (PCCT) is the next-generation CT scanner that enables improved spatial resolution and spectral imaging. For full spectral processing, higher tube voltages compared to conventional CT are necessary to achieve the required spectral separation. This generated interest in the potential influence of thin slice high tube voltage PCCT on overall image quality and consequently on radiation dose. This study first evaluated tube voltages and radiation doses applied in patients who underwent coronary CT angiography with PCCT and energy-integrating detector CT (EID-CT). Next, image quality of PCCT and EID-CT was objectively evaluated in a phantom study simulating different patient sizes at these tube voltages and radiation doses. We conducted a retrospective analysis of clinical doses of patients scanned on a conventional and PCCT system. Average patient water equivalent diameters for different tube voltages were extracted from the dose reports for both EID-CT and PCCT. A conical phantom made of polyethylene with multiple diameters (26/31/36cm) representing different patient sizes and containing an iodine insert was scanned with a EID-CT scanner using tube voltages and phantom diameters that match the patient scans and characteristics. Next, phantom scans were made with PCCT at a fixed tube voltage of 120kV and with CTDIVOL values and phantom diameters identical to the EID-CT scans. Clinical image reconstructions at 0.6mm slice thickness for conventional CT were compared to PCCT images with 0.4mm slice thickness. Image quality was quantified using the detectability index (d'), which estimated the visibility of a 3mm diameter contrast-enhanced coronary artery by considering noise, contrast, resolution, and human visual perception. Alongside d', noise, contrast and resolution were also individually assessed. In addition, the influence of various kernels (Bv40/Bv44/Bv48/Bv56), quantum iterative reconstruction strengths (QIR, 3/4) and monoenergetic levels (40/45/50/55keV) for PCCT on d' was investigated. In this study, 143 patients were included: 47 were scanned on PCCT (120kV) and the remaining on EID-CT (74 small-sized at 70kV, 18 medium-sized at 80kV and four large-sized at 90kV). EID-CT showed 7%-17% higher d' than PCCT with Bv40 kernel and strength four for small/medium patients. Lower monoenergetic images (40keV) helped mitigate the difference to 1%-6%. For large patients, PCCT's detectability was up to 31% higher than EID-CT. PCCT has thinner slices but similar noise levels for similar reconstruction parameters. The noise increased with lower keV levels in PCCT (≈30% increase), but higher QIR strengths reduced noise. PCCT's iodine contrast was stable across patient sizes, while EID-CT had 33% less contrast in large patients than in small-sized patients. At 120kV, thin slice PCCT enables CCTA in phantom scans representing large patients without raising radiation dose or affecting vessel detectability. However, higher doses are needed for small and medium-sized patients to obtain a similar image quality as in EID-CT. The alternative of using lower mono-energetic levels requires further evaluation in clinical practice.

Multi-Temporal Sentinel-1 and Sentinel-2 Data for Orchards Discrimination in Khairpur District, Pakistan Using Spectral Separability Analysis and Machine Learning Classification

Generating orchards spatial distribution maps within a heterogeneous landscape is challenging and requires fine spatial and temporal resolution images. This study examines the effectiveness of Sentinel-1 (S1) and Sentinel-2 (S2) satellite data of relatively high spatial and temporal resolutions for discriminating major orchards in the Khairpur district of the Sindh province, Pakistan using machine learning methods such as random forest (RF) and a support vector machine. A Multicollinearity test (MCT) was performed among the multi-temporal S1 and S2 variables to remove those with high correlations. Six different feature combination schemes were tested, with the fusion of multi-temporal S1 and S2 (scheme-6) outperforming all other combination schemes. The spectral separability between orchards pairs was assessed using Jeffries-Matusita (JM) distance, revealing that orchard pairs were completely separable in the multi-temporal fusion of both sensors, especially the indistinguishable pair of dates-mango. The performance difference between RF and SVM was not significant, SVM showed a slightly higher accuracy, except for scheme-4 where RF performed better. This study concludes that multi-temporal fusion of S1 and S2 data, coupled with robust ML methods, offers a reliable approach for orchard classification. Prospectively, these findings will be helpful for orchard monitoring, improvement of yield estimation and precision based agricultural practices.

Multi-branch residual image semantic segmentation combined with inverse weight gated-control

The loss of pixel-level information in the multi-class segmentation task based on the U-net model results in unclear boundaries and low semantic segmentation accuracy. Aiming at this, a deep multi-branch residual Unet (IWG-MRUN) with fused inverse weight gated-control is proposed to improve the quality of image semantic segmentation. Specifically, we first introduce a deep multi-branch residual module, which used parallel convolution mode to capture the contextual feature to extract the detailed features of the input image at a deeper level. Then, we adopt an inverse weight gated-control module to enhance the diversity of up-sampling information by counterclockwise transmitting attention horizontally to improve the restoration accuracy of up-sampled image pixels. Finally, to obtain finer granularity features from low spatial resolution images, we adopt the different receptive field pyramid attention mechanisms at the highest level of the U-shaped encoder to capture high-level context information at different scales, thereby improving the accuracy of semantic segmentation. The experimental results show that the segmentation accuracy of the proposed algorithm reaches 91.80% and the CCE loss is reduced to 0.21. When compared to the Unet, BiSeNet, DeeplabV3+ and U-net + BLR model, the pixel accuracy of semantic segmentation is improved by 15.0%, 1.98%, 0.9% and 6.5%, respectively. The semantic segmentation model proposed in this paper provides an end-to-end semantic segmentation capability with the enriched finer granularity features of the target boundary and realizes the accurate segmentation of the objects in different categories.

Enhancing the resolution of three‐dimensional migration images based on space‐variant point spread function deconvolution

AbstractImproving the resolution of seismic migration images plays an important role for geophysical interpreters to characterize underground reservoirs. However, the classical image domain least‐squares migration method based on the local‐stationary assumption cannot obtain a satisfactory high‐resolution seismic image due to the significant spatial variant characteristics of the point spread function. To mitigate this problem, we proposed a high‐resolution point spread function deconvolution method and applied it to two‐dimensional cases. Nevertheless, extending the two‐dimensional method to three‐dimensional problems directly would fail due to the intrinsic complexity in three‐dimensional cases. In this study, we resolve the differences encountered in the point spread function deconvolution method for two‐ and three‐dimensional cases and provide specific strategies for achieving high‐resolution imaging with low computational cost when extending the point spread function deconvolution method to three‐dimensional cases. The main schemes include (1) incorporating the analytical expression of the point spread function to guide the generation of three‐dimensional point spread function distributions, (2) extending the point spread function filter calculation method from a two‐dimensional square to a three‐dimensional rectangular prism and (3) interpolating to obtain more compact point spread functions for reducing migration artefacts. Results from the three‐dimensional synthetic Overthrust model and field data set demonstrate that our techniques could effectively enhance the spatial resolution of the migration images with reduced migration artefacts. With these specific strategies, the space‐variant point spread function deconvolution algorithm shows superior performance on three‐dimensional cases at a much lower computational cost compared with the classical least‐squares migration method and the local‐stationary deblurring method. Synthetic tests and real data applications confirm that the space‐variant point spread function deconvolution method has distinct advantages over both two‐ and three‐dimensional problems and can be widely adopted in practice.

Advancing the path to in-vivo imaging in freely moving mice via multimode-multicore fiber based holographic endoscopy.

Hair-thin multimode optical fiber-based holographic endoscopes have gained considerable interest in modern neuroscience for their ability to achieve cellular and even subcellular resolution during in-vivo deep brain imaging. However, the application of multimode fibers in freely moving animals presents a persistent challenge as it is difficult to maintain optimal imaging performance while the fiber undergoes deformations. We propose a fiber solution for challenging in-vivo applications with the capability of deep brain high spatial resolution imaging and neuronal activity monitoring in anesthetized as well as awake behaving mice. We used our previously developed multimode-multicore fiber to record fluorescently labeled neurons in anesthetized mice. Our exhibits a cascaded refractive index structure, enabling two distinct regimes of light transport that imitate either a multimode or a multicore fiber. The has been specifically designed for use in the initial phase of an in-vivo experiment, allowing for the navigation of the endoscope's distal end toward the targeted brain structure. The multicore regime enables the transfer of light to and from each individual neuron within the field of view. For chronic experiments in awake behaving mice, it is crucial to allow for disconnecting the fiber and the animal between experiments. Therefore, we provide here an effective solution and establish a protocol for reconnection of two segments of with hexagonally arranged corelets. We successfully utilized the to image neurons in anaesthetized transgenic mice expressing enhanced green fluorescent protein. Additionally, we compared imaging results obtained with the with larger numerical aperture (NA) fibers in fixed whole-brain tissue. This study focuses on addressing challenges and providing insights into the use of multimode-multicore fibers as imaging solutions for in-vivo applications. We suggest that the upcoming version of the increases the overall NA between the two cladding layers to allow for access to high resolution spatial imaging. As the NA increases in the multimode regime, the fiber diameter and ring structure must be reduced to minimize the computational burden and invasiveness.

Dual-exposure temporal laser speckle imaging for simultaneously accessing microvascular blood perfusion and angiography.

Laser speckle contrast imaging (LSCI) has gained significant attention in the biomedical field for its ability to map the spatio-temporal dynamics of blood perfusion in vivo. However, LSCI faces difficulties in accurately resolving blood perfusion in microvessels. Although the transmissive detecting geometry can improve the spatial resolution of tissue imaging, ballistic photons directly transmitting forward through tissue without scattering will cause misestimating in the flow speed by LSCI because of the lack of a quantitative theoretical model of transmissvie LSCI. Here, we develop a model of temporal LSCI which accounts for the effect of nonscattered light on estimating decorrelation time. Based on this model, we further propose a dual-exposure temporal laser speckle imaging method (dEtLSCI) to correct the overestimation of background speed when performing traditional transmissive LSCI, and reconstruct microvascular angiography using the scattered component extracted from total transmitted light. Experimental results demonstrated that our new method opens an opportunity for LSCI to simultaneously resolve the blood vessels morphology and blood flow speed at microvascular level in various contexts, ranging from the drug-induced vascular response to angiogenesis and the blood perfusion monitoring during tumor growth.

High Spatiotemporal Remote Sensing Images Reveal Spatial Heterogeneity Details of Soil Organic Matter

Soil is the foundation of sustainable agricultural development. Soil organic matter (SOM) is a key indicator for characterizing soil degradation, and remote sensing has been applied in SOM prediction. However, the differences in SOM prediction from different remote sensing data and the ability to combine multi-source and multi-phase remote sensing data for SOM prediction urgently need to be explored. The following research employed Landsat-8, Sentinel-2, and Gaofen-6 satellite data, utilizing a random forest algorithm to establish a SOM prediction model. It aimed to explore the variations in SOM prediction capabilities among these satellites in typical black soil regions. Additionally, the study involved creating multi-phase synthetic images for SOM prediction using Landsat-8 and Sentinel-2 images captured during three years of bare soil periods. Finally, the research examined the ability to combine three satellites to construct high spatiotemporal remote sensing images for SOM prediction. The results showed that (1) using Landsat-8 and Sentinel-2 to extract the principal components of the three-year bare soil period to construct the multi-phase synthetic image for SOM prediction, higher prediction accuracies can be obtained compared with the single-phase images. (2) The highest accuracy can be obtained using multi-phase synthetic images and high spatial resolution images to construct high spatiotemporal remote sensing images and perform SOM prediction (R2 is 0.65, RMSE is 0.67%, MAE is 0.42%). (3) Simultaneously, high spatiotemporal remote sensing images can reach 2 m spatial resolution to reveal the spatial heterogeneity of SOM. The causes of SOM spatial anomalies can be determined after analysis combined with soil degradation information. In subsequent research, SOM prediction should focus more on multi-sensor collaborative prediction.

Hyperspectral low altitude UAV target tracking algorithm based on deep learning and improved KCF

This article presents a novel target tracking algorithm for hyperspectral low altitude UAV, combining deep learning with an improved Kernelized Correlation Filter (KCF). Initially, an image noise reduction method based on principal component analysis with Block-Matching 3D (BM3D), is employed to process redundant information. Subsequently, an image fusion method is utilized to merge the processed hyperspectral image and the high-resolution panchromatic band image to obtain a high spatial resolution image for target enhancement. Following this, YOLOv5 is used to detect the coordinate information of the UAV target in the current frame. Then, The KCF algorithm is used for target tracking in the current frame using kernel correlation filtering. Finally, the Discriminative Scale Spatial Tracker (DSST) is employed to determine the scale information to achieve a multi-scale tracking effect. The experimental results demonstrate that the algorithm presented in this paper surpasses CSK, HLT, and the conventional KCF algorithm in hyperspectral UAV datasets. On average, there is a significant increase in accuracy which is over 17% when using our algorithm.

A spectral and spatial transformer for hyperspectral remote sensing image super-resolution

ABSTRACT Due to the generally low spatial resolution of hyperspectral images (HSIs), early multispectral images lacked corresponding panchromatic bands, and as a result, fusion methods could not be used to enhance resolution. Many researchers have proposed various image super-resolution methods to address these limitations. However, these methods still suffered from issues, such as inadequate feature representation, lack of spectral feature representation, and high computational cost and inefficiency. To address these challenges, a spectral and spatial transformer (SST) algorithm for hyperspectral remote sensing image super-resolution is introduced. This algorithm uses a spatial transformer structure to extract the spatial features between the image pixels and a spectral transformer structure to extract the spectral features within the image pixels. The integration of these two components is applied to HSI super-resolution. After comparative experiments with currently advanced methods on three publicly available hyperspectral datasets, the results consistently show that our algorithm has better performance in both spectral fidelity and spatial restoration. Furthermore, our proposed algorithm was applied to real-world super-resolution experiments in the region of China's Ruoergai National Park, and subsequently, pixel-based classification was conducted on the super-resolution images, the results indicate that our algorithm could also be applied to future remote sensing interpretation tasks.

Anatomy-based correction of kidney PVE on 177Lu\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$^{177}\ ext{Lu}$$\\end{document} SPECT images

BackgroundIn peptide receptor radionuclide therapy (PRRT), accurate quantification of kidney activity on post-treatment SPECT images paves the way for patient-specific treatment. Due to the limited spatial resolution of SPECT images, the partial volume effect (PVE) is a significant source of quantitative bias. In this study, we aimed to evaluate the performance and robustness of anatomy-based partial volume correction (PVC) algorithms to recover the accurate activity concentration of realistic kidney geometries on 177\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$^{177}$$\\end{document}Lu SPECT images recorded under clinical conditions.MethodsBased on the CT scan data from patients, three sets of fillable kidneys with surface-to-volume (S:V) ratios ranging from 1.5 to 2.8 cm−1, were 3D printed and attached in a IEC phantom. Quantitative 177\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$^{177}$$\\end{document}Lu SPECT/CT acquisitions were performed on a GE Discovery NM CT 870 DR camera for the three modified IEC phantoms and for 6 different Target-To-Background ratios (TBRs: 2, 4, 6, 8, 10, 12). Two region-based (GTM and Labbé) and five voxel-based (GTM + MTC, Labbé + MTC, GTM + RBV, Labbé + RBV and IY) methods were evaluated with this data set. Additionally, the robustness of PVC methods to Point Spread Function (PSF) discrepancies, registration mismatches and background heterogeneity was evaluated.ResultsWithout PVC, the average kidney RCs across all TBRs ranged from 0.66 ± 0.05 (smallest kidney) to 0.80 ± 0.03 (largest kidney). For a TBR of 12, all anatomy-based method were able to recover the kidneys activity concentration with an error < 6%. All methods result in a comparable decline in RC restoration with decreasing TBR. The Labbé method was the most robust against PSF and registration mismatches but was also the most sensitive to background heterogeneity. Among the voxel-based methods, MTC images were less uniform than RBV and IY images at the outer edge of high uptake areas (kidneys and spheres).ConclusionAnatomy-based PVE correction allows for accurate SPECT quantification of the 177\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$^{177}$$\\end{document}Lu activity concentration with realistic kidney geometries. Combined with recent progress in deep-learning algorithms for automatic anatomic segmentation of whole-body CT, these methods could be of particular interest for a fully automated OAR dosimetry pipeline with PVE correction.

Fabrication of oscillating metal probe for dynamic scanning microwave microscopy

Abstract A microwave probe plays a critical role in near-field imaging, and there is a continuous effort to develop them through straightforward methods. This study designed and fabricated an oscillating metal probe and used it for scanning microwave imaging of micro-nano structures. The surface smoothness of the cantilever is approximately 19.3 nm after polishing with diamond abrasive paper, and the tip radius is less than 20 nm using electrochemical etching. The impact of metal electrode materials on microwave signals was assessed in the frequency range of 1–20 GHz. The microwave imaging capability of the devised probe was explored through the imaging of a micro-nano structure. The spatial resolution of microwave imaging reached 0.5 μm over a scanning area of 50 μm × 50 μm. This study has far-reaching significance for developing higher-performance microwave probes and advancing scanning microwave microscopy.

Spatial Resolution of Images and Effective Focus Size of Bremsstrahlung of an Improved Compact Betatron SEA-7 with Electron Energy of 7 MeV

Spatial Resolution of Images and Effective Focus Size of Bremsstrahlung of an Improved Compact Betatron SEA-7 with Electron Energy of 7 MeV

Super Resolution Dual-Energy Cone-Beam CT Imaging With Dual-Layer Flat-Panel Detector.

In flat-panel detector (FPD) based cone-beam computed tomography (CBCT) imaging, the native receptor array is usually binned into a smaller matrix size. By doing so, the signal readout speed could be increased by 4-9 times at the expense of a spatial resolution loss of 50%-67%. Clearly, such manipulation poses a key bottleneck in generating high spatial and high temporal resolution CBCT images at the same time. In addition, the conventional FPD is also difficult in generating dual-energy CBCT images. In this paper, we propose an innovative super resolution dual-energy CBCT imaging method, named as suRi, based on dual-layer FPD (DL-FPD) to overcome these aforementioned difficulties at once. With suRi, specifically, a 1D or 2D sub-pixel (half pixel in this study) shifted binning is applied instead of the conventionally aligned binning to double the spatial sampling rate during the dual-energy data acquisition. As a result, the suRi approach provides a new strategy to enable high spatial resolution CBCT imaging while at high readout speed. Moreover, a penalized likelihood material decomposition algorithm is developed to directly reconstruct the high resolution bases from these dual-energy CBCT projections containing sub-pixel shifts. Numerical and physical experiments are performed to validate this newly developed suRi method with phantoms and biological specimen. Results demonstrate that suRi can significantly improve the spatial resolution of the CBCT image. We believe this developed suRi method would greatly enhance the imaging performance of the DL-FPD based dual-energy CBCT systems in future.

A Spatio-Spectral Fusion Method for Hyperspectral Images Using Residual Hyper-Dense Network.

Spatio-spectral fusion of panchromatic (PAN) and hyperspectral (HS) images is of great importance in improving spatial resolution of images acquired by many commercial HS sensors. DenseNets have recently achieved great success for image super-resolution because they facilitate gradient flow by concatenating all the feature outputs in a feedforward manner. In this article, we propose a residual hyper-dense network (RHDN) that extends the DenseNet to solve the spatio-spectral fusion problem. The overall structure of the proposed RHDN method is a two-branch network, which allows the network to capture the features of HS images within and outside the visible range separately. At each branch of the network, a two-stream strategy of feature extraction is designed to process PAN and HS images individually. A convolutional neural network (CNN) with cascade residual hyper-dense blocks (RHDBs), which allows direct connections between the pairs of layers within the same stream and those across different streams, is proposed to learn more complex combinations between the HS and PAN images. The residual learning is adopted to make the network efficient. Extensive benchmark evaluations well demonstrate that the proposed RHDN fusion method yields significant improvements over many widely accepted state-of-the-art approaches.

Full-resolution image restoration for light field images via a spatial shift-variant degradation network.

The light field (LF) imaging systems face a trade-off between the spatial and angular resolution in a limited sensor resolution. Various networks have been proposed to enhance the spatial resolution of the sub-aperture image (SAI). However, the spatial shift-variant characteristics of the LF are not considered, and few efforts have been made to recover a full-resolution (FR) image. In this paper, we propose an FR image restoration method by embedding LF degradation kernels into the network. An explicit convolution model based on the scalar diffraction theory is first derived to calculate the system response and imaging matrix. Based on the analysis of LF image formation, we establish the mapping from an FR image to the SAI through the SAI kernel, which is a spatial shift-variant degradation (SSVD) kernel. Then, the SSVD kernels are embedded into the proposed network as prior knowledge. An SSVD convolution layer is specially designed to handle the view-wise degradation feature and speed up the training process. A refinement block is designed to preserve the entire image details. Moreover, our network is evaluated on extensive simulated and real-world LF images to demonstrate its superior performance compared with other methods. Experiments on a multi-focus scene further prove that our network is suitable for any in-focus or defocused conditions.

Time-Saving 3D MR Imaging Protocols with Millimeter and Submillimeter Isotropic Spatial Resolution for Face and Neck Imaging as Implemented at a Single-Site Major Referral Center.

MR imaging has become the routine technique for staging nasopharyngeal carcinoma, evaluating perineural tumor spread, and detecting cartilage invasion in laryngeal carcinoma. However, these protocols traditionally require in the range of 25 to 35 minutes of acquisition time. 3D sequences offer the potential advantage of time savings through the acquisition of 1-mm or submillimeter resolution isotropic data followed by multiplanar reformats that require no further imaging time. We have iteratively optimized vendor product 3D T1-weighted MR imaging sequences for morphologic face and neck imaging, reducing the average acquisition time of our 3T protocols by 9 minutes 57 seconds (40.9%) and of our 1.5T protocols by 9 minutes 5 seconds (37.0%), while simultaneously maintaining or improving spatial resolution. This clinical report describes our experience optimizing and implementing commercially available 3D T1-weighted MR imaging pulse sequence protocols for clinical face and neck MR imaging examinations using illustrative cases. We provide protocol details to allow others to replicate our implementations, and we report challenges we faced along with our solutions.

The Role of Fluid Mechanics in Coronary Atherosclerotic Plaques: An Up-to-Date Review.

Most acute coronary syndromes are due to a sudden luminal embolism caused by the rupturing or erosion of atherosclerotic plaques. Prevention and treatment of plaque development have become an effective strategy to reduce mortality and morbidity from coronary heart disease. It is now generally accepted that plaques with thin-cap fibroatheroma (TCFA) are precursors to rupturing and that larger plaques and high-risk plaque features (including low-attenuation plaque, positive remodeling, napkin-ring sign, and spotty calcification) constitute unstable plaque morphologies. However, plaque vulnerability or rupturing is a complex evolutionary process caused by a combination of multiple factors. Using a combination of medicine, engineering mechanics, and computer software, researchers have turned their attention to computational fluid mechanics. The importance of fluid mechanics in pathological states for promoting plaque progression, inducing plaque tendency to vulnerability, or even rupture, as well as the high value of functional evaluation of myocardial ischemia has become a new area of research. This article reviews recent research advances in coronary plaque fluid mechanics, aiming to describe the concept, research implications, current status of clinical studies, and limitations of fluid mechanic's characteristic parameters: wall shear stress (WSS), axial plaque shear (APS), and fractional flow reserve (FFR). Previously, most computational fluid dynamics were obtained using invasive methods, such as intravascular ultrasound (IVUS) or optical coherence tomography (OCT). In recent years, the image quality and spatial resolution of coronary computed tomography angiography (CCTA) have greatly improved, making it possible to compute fluid dynamics by noninvasive methods. In the future, the combination of CCTA-based anatomical stenosis, plaque high-risk features, and fluid mechanics can further improve the prediction of plaque development, vulnerability, and risk of rupturing, as well as enabling noninvasive means to assess the degree of myocardial ischemia, thereby providing an important aid to guide clinical decision-making and optimize treatment.

A finely segmented semi-monolithic detector tailored for high-resolution PET.

Preclinical research and organ-dedicated applications use and require high (spatial-)resolution positron emission tomography (PET) detectors to visualize small structures (early) and understand biological processes at a finer level of detail. Researchers seeking to improve detector and image spatial resolution have explored various detector designs. Current commercial high-resolution systems often employ finely pixelated or monolithic scintillators, each with its limitations. We present a semi-monolithic detector, tailored for high-resolution PET applications with a spatial resolution in the range of 1mm or better, merging concepts of monolithic and pixelated crystals. The detector features LYSO slabs measuring (24×10×1)mm3, coupled to a 12×12 readout channel photosensor with 4mm pitch. The slabs are grouped in two arrays of 44 slabs each to achieve a higher optical photon density despite the fine segmentation. We employ a fan beam collimator for fast calibration to train machine-learning-based positioning models for all three dimensions, including slab identification and depth-of-interaction (DOI), utilizing gradient tree boosting (GTB). The data for all dimensions was acquired in less than 2h. Energy calculation was based on a position-dependent energy calibration. Using an analytical timing calibration, time skews were corrected for coincidence timing resolution (CTR) estimation. Leveraging machine-learning-based calibration in all three dimensions, we achieved high detector spatial resolution: down to 1.18mm full width at half maximum (FWHM) detector spatial resolution and 0.75mm mean absolute error (MAE) in the planar-monolithic direction, and 2.14mm FWHM and 1.03mm MAE for DOI at an energy window of (435-585)keV. Correct slab interaction identification in planar-segmented direction exceeded 80%, alongside an energy resolution of 12.7% and a CTR of 450ps FWHM. The introduced finely segmented, high-resolution slab detector demonstrates appealing performance characteristics suitable for high-resolution PET applications. The current benchtop-based detector calibration routine allows these detectors to be used in PET systems.