In this study, a field experiment of soil passivation and low accumulation-crops was carried out for typical northern alkaline cadmium and lead compound-polluted farmland soil. Calcite was used as the main passivation material, and a small amount of slaked lime, zeolite powder, and biochar were combined to form a group passivation agent. The effects of passivators on soil physicochemical properties, bioavailability of the heavy metals Cd and Pb, and the yield and plant (stalk and seed) content of heavy metals Cd and Pb in low-accumulation maize were investigated under different grouping conditions of calcite+slaked lime (CL), calcite+zeolite (CZ), calcite+biochar (CB), and calcite+slaked lime+zeolite+biochar (CLZB). The results showed that:① all applications of passivating agent ensured the normal growth of maize and slightly increased the 1000 grain weight and maize yield. ② The effects of different calcite-based passivators on soil physical and chemical properties were different. The CL, CZ, CB, and CLZB treatments increased soil pH by 0.46, 0.25, 0.12, and 0.13 units, respectively, but had no significant correlation with soil fertility index (P>0.05). ③ DTPA leaching and ion exchange state contents of Cd and Pb in soil could be significantly reduced by different calcite-based combinations with passivators, and the reduction rates of Cd and Pb in DTPA leaching were 49.36% and 72.55%, respectively. The reduction rates of ion exchange Cd and Pb contents were 55.39% and 78.52%, respectively. ④ The contents of Cd and Pb in stems, leaves, and grains of low-accumulation maize were further reduced by different passivating agents. The contents of Cd and Pb in the stems and leaves of maize were reduced by 45.93% and 67.00% after CLZB treatment, and the contents of Cd and Pb in grains were decreased by 25.17% and 46.62%, respectively. Moreover, the contents of Cd and Pb in DTPA extraction and ion exchange states were significantly positively correlated with the contents of Cd and Pb in corn stems, leaves, and grains (P<0.01). The results showed that the combined use of combination passivators and low-accumulation crop varieties can obtain better restoration effects in the remediation of cadmium and lead combined-polluted farmland in the middle alkaline soil in northern China.