Sensoneural Hearing Loss Research Articles

Состояние слуховой функции у детей-воспитанников детских домов, эвакуированных из зоны военных действий

In this study, the structure and frequency of hearing impairment in children who lived at various times in the territories of military operations were studied. The high prevalence of otorhinolaryngological diseases, combined with low detectability, entails formidable complications, leads to a decrease in the quality of life of the child and the family as a whole, and negatively affects the general level of public health. In total, during the study, 398 children aged 5 to 16 years old were examined, who were in the temporary accommodation center of the Romashka children’s resting camp. The children are students of orphanages in the Donetsk People’s Republic (DPR) and the Luhansk People’s Republic (LPR) evacuated from the war zone in the first days of the Special Operation. There were 216 girls (54.3%) and 182 boys (45.7%) among them. The average age of children was 8.5 years. Hearing loss was detected in 33 children (8.3%). Two children (0.5%) had a severe form of sensorineural hearing loss of 3–4 degrees. Two children (0.5%) had a mild form of sensorineural hearing loss of 1–2 degrees. Four children (1%) had unilateral chronic sensorineural hearing loss. The diagnosis of otitis media with effusion was established in 20 children (5%), tubo-otitis, in three patients (0.8%). Suspicion of an anomaly in the development of the middle ear, in 2 children (0.5%). Examination of children in orphanages evacuated from the DPR and LPR did not reveal a high prevalence of hearing impairment. Sensoneural hearing loss: 2%, conductive hearing loss: 6.3%. The results of the work demonstrate a wide potential for improving hearing health in the examined children. Active diagnostics of hearing pathology is shown to all children in orphanages. After treatment of conductive hearing pathology, mandatory audiological monitoring is indicated, despite the subjective improvement in hearing.

APPLICATION OF EYE-TRACKING TECHNOLOGY DUAL EYE TRACKING (DUET) IN THE STUDY OF COOPERATION BETWEEN CHILDREN WITH ATYPICAL DEVELOPMENT AND ADULTS IN THE LEARNING PROCESS

A technological breakthrough in simultaneously tracking the visual behavior of two people with an eye tracker (DUET) allows you to explore how a child perceives the world and how an adult (teacher) infl uences it. It became possible to more objectively trace the transformation of a child’s perceptual processes under the infl uence of learning (Monroy, Chen, Houston, Yu, ). An analysis of the gaze movements allows us to model the learning process as the emergence and dynamic transformation of an intersubjective connection between the perception-action systems of a child and an adult (Shvarts, ). Synchronous registration of the dyad’s eye movements was carried out by two portable trackers in the form of Pupil Headset goggles. A comparative study was carried out on a sample of preschoolers - years old: typically developing children and children with hearing impairment after cochlear implantation (sensoneural hearing loss, ICD- class H). An analysis of the ways in which the gaze of the adult-child dyad moves makes it possible to model the learning process as the emergence and dynamic transformation of an intersubjective connection between the perception-action systems of a child and an adult. Comparison of gaze patterns showed that contrasting groups of children use different perceptual strategies in the learning process: the specifi city of eye movements of contrasting groups is manifested in the perceptual actions themselves and the pattern of eye movements relative to fi xations in relevant areas corresponding to the task. It was found that the oculomotor activity of an adult changes in the process of interaction with children of contrasting groups and is organized taking into account the specifi c features of the child’s perceptual activity. Differences are manifested in the degree of synchrony of fi xations and the similarity of the trajectories of gaze movements of an adult and a child. An important result of using the DUET technology on contrast samples is the fact that the process of teaching/ learning caused a mutual transformation of the perceptual strategies of both the adult and the child. The perceptual connection of the dyad is clearly manifested in tracking, identifying and controlling perceptual actions as a previous phase, the emergence of compatibility.

Дозозависимый эффект снижения слуха на фоне приема цисплатина

Cisplatin is a cystostatic agent with a ototoxic side effect. Modern chemotherapy protocols aim to maintain high efficiency against malignant tumors with minimal complications. It is known that one of the side effects of the drug is cisplatin-induced sensoneural hearing loss. Our study research hearing loss with the use of cisplatin depending on the total dose of the drug in clinical practice and identifying target cells in the structure of the inner ear in experiment. A total of 117 patients using cisplatin to treat tumors of various locations were studied, among whom hearing loss was revealed in 28% of cases. Hearing loss predominantly affected the high-frequency region above 8000 Hz and depended on the total dose of cisplatin. We carried out the experimental part of the work on BALB/C mice. To model toxic hearing loss, we used 2 cisplatin administration protocols: a single dose of 12 mg per kg intraperitoneally and a dose of 3 mg/kg sequentially for 7 days. After the administration of cisplatin, a decrease in hearing was recorded according to ABR and DPOAE in all animals, which was more prominent among animals with a single dose of the drug. Histological examination of preparations of the cochlea of animals exposed to the toxic effects of cisplatin showed damage to the structures of the spiral ganglion, stria vascularis and outer hair cells. Variety of damage depended on the dose of the drug.

A Case Study of Senso Neural Hearing Loss Healed Successfully Using Yoga Prana Vidya (YPY) Healing Protocols

Introduction: When some damage to the inner ear occurs, it results in senso neural hearing loss (SNHL). Common causes include exposure to loud noises, genetic factors, or the natural aging process. Medical recommendations generally include hearing aids or assistive devices. This paper presents a case of SNHL treated successfully using Yoga Prana Vidya Healing techniques helping the patient to fully regain normal hearing capabilities. Method: This paper uses case study method of investigation by going through patient’s medical records, YPV healer’s records and patient’s feedback. Results: After two days of healing sessions, the patient experienced bearable noise level, By the end of 9 sessions, noise almost reduced and hearing was improved by 80%, and PTA test score reduced from 41 to 28. She attended and learnt Healer development programme Level 1 (HDP L1) course, and she continued with self-healing. A follow up after a year and half showed perfectly normal hearing with PTA score of 13. Conclusions: Yoga Prana Vidya (YPV) healing protocols have cured the Senso hearing loss in this case, and further research is recommended with appropriate sample size and methodology. In view of being an integrated and holistic system, it will be helpful for the frontline health workers such as doctors and nurses to learn and practice YPV healing protocols to complement their specialties.

Seroprevalence of Cytomegalovirus infection among pregnant women in some selected hospitals in Lokoja Metropolis, Kogi State, Nigeria

Cytomegalovirus is one of the most common viruses which causes congenital defects in babies from infected mothers. Sensoneural hearing loss (SNHL) and neurodevelopmental delay are typical occurrences in childhood resulting from congenital defects which presents no symptoms at birth. The aim of this study was to determine the cytomegalovirus IgM infection among pregnant women attending antenatal clinics at KSSH and FMC in Lokoja metropolis, Kogi State, Nigeria. A total of 184 serum samples were collected and analyzed using CMV IgM ELISA kit diagnostic Automation, INC (USA). The study revealed that out of the 184 samples collected, 40 turned out positive for CMV IgM antibodies giving a prevalence of 21.7% while the negative sample result had a prevalence of 78.3%. a total of 92 samples each was collected from both hospitals; KSSH had 30 CMV IgM positive samples having a percentage 32.6% and FMC with 10 CMV IgM having a percentage of 10.86%. Based on the research, there was no significant association between the risk factors such as marital status, type of marriage, occupation and scarification related to the infection. This could be due to the limited number in sample size. Other socio-economic factors that had statistical significant p value with the infection were education (0.035), hand wash (0.027) and previous history of blood transfusion (0.003). The study has shown the need for sensitization of the populace especially to pregnant women, the need for constant and proper personal hygienic practices be done to reduce the risk of infection and possibly stop its transmission to fetus. In addition, inclusion of screening for cytomegalovirus antibodies among blood donors may be useful tool in preventing transmission of cytomegalovirus to blood recipients.

Hypoparathyroidism-retardation-dysmorphism syndrome-Clinical insights from a large longitudinal cohort in a single medical center.

BackgroundHypoparathyroidism, retardation, and dysmorphism (HRD) Syndrome is a rare disease composed of hypoparathyroidism, retardation of both growth and development, and distinctive dysmorphic features. Here, we describe the long-term morbidity and mortality in a large cohort of HRD patients and suggest recommendations for follow up and treatment.MethodsMedical records of 63 HRD syndrome patients who were followed at Soroka Medical Center during 1989–2019 were reviewed retrospectively. Information regarding demographics, medical complications, laboratory findings, and imaging studies was collected.ResultsThe mortality rate was 52%. The main causes of death were infectious diseases including pneumonia, septic shock, and meningitis. Multiple comorbidities were found including brain anomalies in 90% of examined patients (basal ganglia calcifications, tightening of corpus callosum, Chiari malformation, hydrocephalous, and brain atrophy), seizures in 62%, nephrocalcinosis and/or nephrolithiasis in 47%, multiple eye anomalies were recorded in 40%, bowel obstructions in 9.5%, and variable expression of both conductive and senso-neural hearing loss was documented in 9.5%.ConclusionHRD is a severe multisystem disease. Active surveillance is indicated to prevent and treat complications associated with this rare syndrome.

Waardenburg-Shah syndrome rare and challenging case report from Somalia.

Introduction and importanceWaardenburg-Shah disorder could be an uncommon autosomal recessive inherited ailment characterized by aganglionic megacolon with a high mortality rate. Babies born with Waardenburg syndrome may have typical features of hair, skin and eye pigmentary abnormalities, and hearing loss. Here we present a case with typical presentation of Waardenburg Shah syndrome.Case presentationThis is a case of neonatal intestinal obstruction caused by a rare syndrome known as Waardenburg-Shah syndrome, with clinical manifestations of abdominal distension, bilious vomiting, and a history of delayed meconium passage with a family history of variant forms of this syndrome. The patients underwent first laparotomy, which found no atresia.post op colongarphy revealed a narrowed colon. Then reoperated, and a biopsy was taken and opened ileostomy. The pathology result showed gangilion negative. The patient was lost due to uncontrollable sepsis at the age of 2 months.Clinical discussionWaardenurg syndrome is a congenital audito-pigmentary syndrome first described in 1951.Waardenurg syndrome is classified into four types, WS1 to WS4, and they share the common presence of congenital sensoneural hearing loss and pigmentary defects. The diagnosis of WS has major and minor criteria. The definitive management of this disorder involves surgical removal of aganglionic segment of the bowel and connecting functioning gangilioic bowel to the anus.ConclusionShah-Waardenburg syndrome TYPE-4 is a relatively unusual syndrome characterized by a higher prevalence of whole colonic aganglionosis with or without small bowel involvement, resulting in substantial morbidity and mortality in the neonatal age range.

АЙТРЕКИНГ ИССЛЕДОВАНИЯ ИСПОЛЬЗОВАНИЯ РАЗНЫХ ФОРМ ИНСТРУКЦИИ В ОБУЧЕНИИ ДЕТЕЙ С НАРУШЕНИЕМ СЛУХА

Background. It is analyzed how the method of eye movement registration can be used to study the learning processes of children with hearing impairment. On the basis of oculomotor activity data, diffi culties are identifi ed that impede the learning of children with hearing impairment, which contributes to the discovery of eff ective ways of learning. A separate research issue is the search for the eff ective use of diff erent forms of instruction. Objective. Eye-tracking study of learning diffi culties with diff erent forms of instruction (as diff erent forms of multimodal means of establishing joint attention). Sample. Th e study sample consisted of 15 preschool children with hearing impairment (sensoneural hearing loss, class H90 according to ICD-11), eight girls, seven boys, mean age 5.4±0.8. Methods. A task was used in the form of a correction test to fi ll in the fi gures (according to the Pieron-Ruser method). To understand diff erent forms of instruction in 4 series of the experiment, the combination of the speech form and the use of action in explaining the rule for fi lling in the fi gures varied. Th e main method is the method of eye movement registration using the PLabs portable tracker-the eye tracker. Results. Th e most important criterion for the eff ectiveness of diff erent forms of instruction is the time from the beginning of the presentation of the instruction to the fi rst fi xation on the target object and the duration of attention delay in non-target areas. With multimodal instruction, longer fi xations are observed in relevant areas and short fi xations in irrelevant areas, fi xations are more oft en and faster in relevant areas. With the transition to independent analysis, tasks at the beginning of fi xation in relevant and irrelevant areas become reduced in time and quantity, and then begin to take on an increasingly long character. Conclusion. A diff erent form of instruction allows you to restructure the perception of a child with a hearing impairment, focusing attention on the elements that are relevant to the task. Th e most eff ective is the simultaneous use of multimodal means of explaining instructions to attract and regulate attention.

Indicators of the peripheral and central departments of the auditory analyzer according to the threshold tone audiometry and acoustic impedansometry data in participants of combat operations with a different course of sensoneural hearing loss

Aim: study of the characteristics of the acoustic stapedius-muscle reflex in conjunction with the data of threshold tone audiometry in combatants with different dynamics of the course of sensorineural hearing loss. Materials and methods: The characteristics acoustic stapedius-muscle reflex and the indicators of threshold tonal audiometry in combatants with different dynamics of sensorineural hearing loss were conducted. 60 military personnel were examined: group 1, with positive dynamics after treatment, group 2, in which progression sensorineural hearing loss took place, 30 people per group. Results and discussion: The study showed that patients who received combat acutrauma showed significant changes in the qualitative and quantitative characteristics of the acoustic stapedius-muscle reflex, which may indicate that they have disorders in the brainstem of the auditory analyzer. In patients with progressive sensorineural hearing loss, these disorders are more pronounced. Thus, they observed a significant (p<0.01) decrease in amplitude not only compared to the control, but also with the indicators of the group with positive dynamics. In addition, in the group with progressive course (group 2) there is a greater "dissociation" of acoustic stapediusmuscle reflex – a larger number of patients with no acoustic stapedius reflex, "asymmetric" acoustic stapediusmuscle reflex. When examining patients with combat acutrauma, we recommend examining both the peripheral (according to threshold tonal audiometry) and brainstem (according to acoustic stapedius-muscle reflex) department of the auditory system, which will not only identify disorders and prescribe the necessary treatment, but also assess the severity and predict the course of disorders in such patients. Therefore, acoustic stapedius-muscle reflex and its amplitude indicators should be used as diagnostic and prognostic criteria when conducting expert examinations of this category of patients. Conclusions: 1. In combat acutrauma there are violations both in the peripheral department of the auditory analyzer according to the threshold tonal audiometry, and in the central (brainstem) according to acoustic stapedius-muscle reflex. 2. In combat acutrauma there is a significant (p<0,01) decrease in the amplitude of acoustic stapediusmuscle reflex, more pronounced in fighters with progressive SNP. 3. "Asymmetry" of acoustic stapedius-muscle reflex, pronounced decrease in the amplitude of the acoustic reflex, "dissociation" of acoustic reflex indicators with the results of audiometric examination is not only a typical sign of hearing loss in fighters with acute trauma, but can be a prognostic marker and one of the criteria disorders in this category of patients. 4. When examining patients with combat acutrauma, it is advisable to study the characteristics of acoustic stapedius-muscle reflex.

Вроджена цитомегаловірусна інфекція: рекомендації ICCRG та аспекти менеджменту, що знаходяться на етапі клінічних випробувань

Вроджена цитомегаловірусна (ЦМВ) інфекція залишається причиною сенсоневральної втрати слуху і аномалій розвитку нервової системи у новонароджених в розвинених країнах світу, що рідко діагностується. Відсутність уніфікованих рекомендацій негативно відбивається на глобальних зусиллях знизити частоту вроджених аномалій, асоційованих із ЦМВ. Власні катамнестичні спостереження за дітьми з мальформаціями нервової системи і сенсоневральними порушеннями, а також оцінка імунологічної відповіді на ЦМВ у вагітних і в період новонародженості ініціювали проведення поглибленого аналізу сучасної світової літератури. У статті подані напрямки мінімізації ризику вродженої цитомегаловірусної інфекції, що реалізуються в клінічних рекомендаціях, заснованих на висновках провідних світових експертів з виявлення та менеджменту вродженої цитомегаловірусної інфекції у вагітних і новонароджених, також окреслені перспективи менеджменту, що знаходяться на етапі клінічних випробувань.

Ototoxicity in some Cancer Patients

To review the outcome in cancer patients who was treated with Cisplatin and other ototoxicity drugs in 6 mounts period in Oncology Department, KOC Stara Zagora. This study suggests that there is a correlation between increase of the Sensoneural hearing loss and combination of Cisplatin and other groups of drugs by some treatment cancer patients.

The significance of microanatomy of the round window in terms of cochlear implantation

Sensoneural hearing loss is a polyetiological disease, which is often a secondary reflection of systemic pathology and is associated with damage of the cochlea and auditory nerve receptors. An important point in the surgical stage of cochlear implantation is the introduction of an implant active electrode into the cochleostomy spiral channel through the cochleostoma or round window. However, the issue of intra-cochlear structures surgical trauma in such surgical intervention seems to be very important, as it may reduce the success of subsequent rehabilitation. Therefore, the study of the anatomy of the round window and adjuscent areas was the objective of this work.

A CASE OF SENSONEURAL HEARING LOSS MANAGED WITH HOMOEOPATHIC SIMILIMUM- AN EVIDENCE BASED CASE REPORT

Sensoneural hearing loss (SNHL) is most common form of hearing loss world-wide. SNHL results from lesions of the cochlea, 8th nerve and central auditory pathways. The causes of SNHL may be congenital, traumatic, infectious, inflammatory, iatrogenic, neoplastic and senile. The development of drugs to treat or prevent SNHL has proven challenging. In modern system of medicine this disease is difficult to treat as treatment is directed towards cause only. Rehabilitation with hearing aids and other devices are also necessary for management of such cases. This article is about a patient of 73 years of age, who was suffering from senile SNHL and improved with homoeopathic medicine, Baryta carb 200, and without need of hearing aid device.

Combined Diagnostic Value of Both CT and MRI in Pre-Operative Evaluation of Cochlear Implant Patients

AbstractBackground: Cochlear implantation is considered an acceptable treatment for severe to profound sensorineural hearing loss with normal cochlea and cochlear nerve. CT is the best modality for evaluation of bony labyrinth and MRI is the best modality to evaluate membranous labyrinth so combined CT and MRI is mandatory for preoperative evalu-ation for cochlear implantation, radiologist should be familial with absolute and relative contraindication of cochlear im-plantation.Aim of Study: The aim of this study is to evaluate the role of HRCT and MRI in pre-operative assessment of cochlear implantation candidates.Patients and Methods: Our study included 60 patients (120 ears) 39 of them were males while 21 were females. The age of our selected patents ranged from 2 to 60 years with a mean of 15.8 years most of them were in pediatric age group 2-10 years representing 60%. The present study included patients with bilateral profound sensory neural hearing loss, minimum age of eligibility is 1 year, both sexes will be included. We excluded pediatric age group >1 year. All patients were subjected to the clinical evaluation. Computed Tomog-raphy (CT), all CT studies (60 figs) were obtained using a 320-row multidetector CT scanner (Aquilion One Toshiba Medical Systems, Otawara, Japan) installed in Tanta University Educational Hospital.Magnetic Resonance Imaging (MRI), all MRI studies (60 figs) were obtained using a closed MRI machine (General Electric SIGNA) HS (high speed) with magnets of intensity field 1.5T.Results: Combined HRCT and MRI revealed a normal appearance of the labyrinth and internal auditory canal in 44 (88 ears) patients (73%). In 16 (32 ears) patients (26%) had abnormalities of the labyrinth; 10 patients (16%) of them had congenital anomalies and 6 patients (10%) had acquired Sensoneural Hearing Loss (SNHL). Ten patients (16%) had congenital abnormalities of inner ear bilaterally; absent cochlea (n=3) represented 5%, IP type I (n=2) represented 3%, IP type II (n=4) represented 6%, common cavity (n=1) represent about 2%, absent vestibule (n=3) represented 5%, dilated vestibule (n=6) represented 10%, dilated vestibular aqueduct (n=5) represented 8% and dysplastic semicircular canals (n=4) represented 7%. The cochlear nerve was normal in 57 figs (95%), while two patients (3%) had absent nerve, and one patient (2%) presented with atrophied cochlear nerve. Nar-rowed internal auditory canal (n=3) represented 5%. Six patients (10%) had acquired sensoneural hearing loss after meningitis, labyrinthitis, otitis media, trauma and sequalae of old age. Calcifications within the cochlea and in the semicircular canals caused by labyrinthitis ossificans (n=3) represented 5% and otosclerosis (n=1) represented about 2%. In current study, we found 4 ears with narrow IAC and absent vestibulocochlear nerve, 2 ears with narrowed IAC and atro-phied small sized vestibulocochlear nerve. In all of them the assessment of VCN were done using 3D MRI.Conclusion: Combined HRCT and MRI studies are man-datory for evaluation of inner ear, the radiologist must be familiar with imaging findings that absolutely contraindicate implantation (Cochlear aplasia, cochlear nerve aplasia and labyrinthine aplasia), and with those that relatively contrain-dicate implantation (labyrinthitis ossificans, other inner ear dysplasia) and with other findings that could significantly alter or complicate surgery (hypoplastic mastoid process, facial nerve dehiscence, oto-mastoiditis).

Rare Cause of Facial Nerve Palsy (Petrous Apex Cholesteatoma)–Case Report and Review of Literature

The petrous apex is a pyramid-shaped struc­ture that is formed by the medial portions of the temporal bone. It is obliquely positioned within the skull base, with its apex pointing anteromedially and its base located postero­laterally. The petrous apex is bounded by the inner ear structures laterally, the petro-occipital fissure medially, the petrosphenoidal fissure and ICA anteriorly, and the posterior cranial fossa behind. Given its location, the petrous apex is susceptible to multiple pathologic processes which may be Inflammatory, developmental, vascular, benign and malignant lesions. We present a rare case of a 39 year old Male who presented wit unilateral facial nerve palsy and sensoneural hearing loss and was then diagnosed as petrous apex Cholesteatoma. Patient was treated surgically by Transchoclear trasnlabrynth technique.

Herpesvirus infection in children with high grade sensoneural hearing loss

Clinical and audiological investigation of 100 children with indications for cochlear implantation was made. Indirect signs of intrauterine infection were identified, as well as the presence of predisposing factors to the development of exudative otitis media. During the investigation frequency of exudative otitis media (up to 21%) in children with high grade sensoneural hearing loss was made. The severity of lymphoproliferative syndrome and it’s combination with herpesvirus infection markers (Cytomegalovirus, Epstein-Barr virus). It was found out, that in group of patients with combination of high grade sensoneural hearing loss and exudative otitis media lymphoproliferative syndrome in more, than 77% cases had herpesvirus ethiology and significantly exceed the same data in group of patients with isolated hearing loss.

The advanced methods of diagnostics and electroacoustic correction of hearing in children with sensoneural hearing loss

The problem of hearing loss and deafness in children is of great social importance due to the increasing incidence of hearing impairments. According to WHO forecasts, by 2020, the number of people with socially significant hearing defects is expected to increase by more than 30%. The article presents the methods of hearing loss diagnostics in preschool children by means of voice-threshold audiometry, tympanometry, acoustic reflexometry and game audiometry, which makes it possible to detect the minimal auditory disorders. Electroacoustic correction of hearing was conducted by means of advanced digital programmable BTE hearing aids (CA), Oticon (Denmark), with customized inserts.

Simulation of sensoneural hearing loss in the experiment

Numerous environmental factors, including noise, have adverse effect on the hearing aid. The authors conducted an experimental study with the participation of 34 white mongrel rats and suggested a method of simulation of sensorineural hearing loss caused by the exposure of 90 dB wide-band noise with simultaneous immobilization of animals. The development of hearing loss was confirmed by the results of recording the delayed induced otoacoustic emission. After removal of the rats from the experiment, histological preparations of animals’ cochlea were made and examined under light microscopy. The main group of rats had dystrophic, destructive changes in the structures of the spiral organ and the spiral ganglion. This hearing loss «model» can be used for study of medications in sensorineural hearing loss.

Исследование эффекта ототоксичности у детей, получавших химиотерапию препаратами платины

Platinum containing chemotherapy regimens are widely used in the treatment of pediatric cancer. The irreversible bilateral sensoneural hearing loss is associated with cisplatin and carboplatin. The aim of our study was to evaluate risk factors and frequency of platinum-induced ototoxicity in children. 113 children were eligible in our study. All patients had normal hearing before the start of therapy. Bilateral sensoneural hearing loss was revealed in 25.7% of children. Younger age (before 5 y.o.), preceding cranial radiotherapy, treatment with carboplatin and cisplatin, cumulative dose of cisplatin more than 300 mg/m 2 increased the risk of hearing loss.

Tympanic cavity obliteration with fat tissue

The article presents a case of the middle ear obliteration in a 45 years old female patient that complained of a long-term continuous otorrhea and underwent 4 surgeries for congenital middle ear development abnormality (microtia, external auditory canal (EAC) atresia), paraauricular fistula and stage 3 chronic sensoneural hearing loss. The work provides detailed description of the course of interference that resulted in the fact, that no complaints of the operated ear have been observed for 12 months. Therefore, the fat tissue obliteration of tympanic cavity may be used as the method of choice in case of treatment of post-surgical cavity without result in patients with the chronic suppurative otitis media in the cases where reconstructive hearing improvement surgery is impossible or is not indicated. The latter is observed in the patients with the expressed sensoneural hearing loss.