Role In Folk Medicine Research Articles

Effect of Bidens tripartita leaf supplementation on the organism of rats fed a hypercaloric diet high in fat and fructose

Herbs play an important role in folk medicine, and scientific research has confirmed the properties of their use as an alternative treatment, including the treatment and mild correction of metabolic disorders during disease. Trifid bur-marigold (Bidens tripartita) is a pharmacopoeial herbal raw material that is widely used in clinical practice as an external remedy for skin lesions and as an internal remedy for digestive and respiratory disorders. In this work, the general effect of dried leaves of B. tripartita on physiological activity and metabolic processes in model animals on a high-calorie diet was determined. For the experiment, three groups of 18 male white laboratory rats were formed and fed a hypercaloric diet (increased fat content and 20% fructose solution instead of water) for 27 days, in addition to 0.4% and 4.0% dried leaves of B. tripartita. The consumption of 0.4% and 4.0% of the medicinal plant resulted in a significant delay in the body weight gain and the average daily weight gain of the rats compared to the control group. Dried leaves of B. tripartita in the diet of rats decreased the relative weight of the thymus and increased the relative weight of the brain, and at a dose of 4.0%, increased the relative weight of the lungs and individual large intestines (cecum and colon). Dietary supplementation with B. tripartita caused an increase in globulin concentration and changes in protein coefficient. Blood parameters such as: urea, urea nitrogen, inorganic phosphorus, glucose and bilirubin levels changed depending on the dose. In the general blood test, consumption of dried leaves of B. tripartita caused a decrease in hematocrit, hemoglobin concentration and platelet count, but increased the number of eosinophils. Bidens tripartita at both concentrations significantly increased ALT activity with a corresponding change in the blood De Ritis ratio. The addition of 20 g of B. tripartita leaves to the diet increased alkaline phosphatase activity and decreased alpha-amylase activity, while 200 g increased blood gamma-glutamyltransferase activity. At the end of the experiment, the rats' orientation activity, determined in the open field, changed according to the herb dose consumed: 0.4% leaves caused an increase and 4.0% a decrease. Physical activity was reduced and emotional state increased, regardless of the dose of dried B. tripartita leaves, compared to the control group of animals. The results obtained show that the addition of B. tripartita dried leaves as a dietary supplement to a high-calorie diet is safe, does not cause pathological changes or side effects, and has a significant effect on metabolic processes. This provides theoretical support for the use of B. tripartita dried leaves in the manufacture of nutraceutical and pharmacological products for the correction of metabolic disorders in humans and animals. The doses and duration of their application require further studies.

Four new phenolic constituents from root barks of Paeonia ostii

The Paeonia ostii, also known as "Feng Dan" have a crucial role in folk medicine to treat lumbar muscles strain, knee osteoarthritis and cervical spondylosis. In this study, four new phenolic compounds, specifically Paeoniaostiph A–E (1–4) phenolic compounds were characterised through spectroscopic techniques, including 1D and 2D NMR, HRESIMS, UV, IR, and electronic circular dichroism computations to explore their structures. Cytotoxicity and NO production inhibition of the new phenolic compounds were also studied. The results of the cytotoxicity experiment showed that compound 1 is cytotoxic to two human cancer cell lines with IC50 values ranging from 13.3 to 13.5 μM. Compounds 1 and 2 showed certain inhibitory activity on NO production. This is the first report on isolating the components from natural sources.

A Traditional Life Plant Kalanchoe Pinnata: Phytochemical and Pharmacognostical Studies

Kalanchoe is a plant that grows approx. 5 feet tall. It’s also known as 'air plant’. This review presents of detailed of phytochemical and medicinal properties present in the plan kalanchoe pinnata. This plant contains a wide range of active compounds. From phytochemical studies we got the different type of alkaloids, glycosides, phenolic compound, flavonoids, etc. and the pharmacological properties are antioxidant, antiseptic, antidiabetic, anti-cancer, anti-microbial, anti-allergic wood healing activities and many more. The botanical description includes information on its morphology, distribution, and cultivation requerment.Traditional uses encompass its role in folk medicine across different cultures, treating ailments such as wounds, respiratory conditions, and gastrointestinal disorders. In ethnomedicine, it is known for its anthroposophical and tocolytic effects in pregnant women. Also, it is used to facilitate. dropping of placenta during childbirth. In many clinical trials have to be carried out in order to commercialize the potential pharmaceutical uses of the plant for which one should thoroughly know about the pharmacogenetic properties of the plant kalanchoe pinnata.

Antioxidant and Anti-Inflammatory Activities of Stellera chamaejasme L. Roots and Aerial Parts Extracts.

Natural products, mainly plants, have a crucial role in folk medicine. Particularly, Stellera chamaejasme L. has been traditionally used in Mongolian medicine to treat various diseases, including chronic tracheitis, tuberculosis, and psoriasis. In this study, ethanol (EtOH) and dichloromethane (DCM) extracts of its roots (R) and aerial parts (AP) were evaluated for their antioxidant and anti-inflammatory activities. Thin-layer chromatography demonstrated the presence of flavonoids, namely kaempferol and quercetin-3-O-glucopyranoside, only in the EtOH-AP. Conversely, it showed that kaempferol, quercetin-3-O-glucopyranoside, coumarin, luteolin, rutin, morin, and riboflavin were not present in the other three extracts. The S. chamaejasme extracts exhibited strong antioxidant activity. In addition, the roots extracts presented the highest antioxidant activity against peroxyl radicals, with the EtOH-R being the most potent (IC50 = 0.90 ± 0.07 µg/mL). S. chamaejasme extracts also efficiently inhibited the production of one of the main pro-inflammatory cytokines, interleukin (IL)-6, in a dose-dependent manner by lipopolysaccharide-stimulated macrophages. Particularly, DCM-R was the strongest extract, reducing ≈ 91.5% of the IL-6 production. Since this extract was the most effective, gas chromatography-mass spectrometry (GC-MS) analyses were performed and demonstrated the presence of two fatty acids (palmitic acid and 9-octadecenoic acid), one fatty alcohol (1-hexadecanol), and one triterpenoid (squalene) that can contribute to the observed bioactivity. Herewith, S. chamaejasme extracts, mainly DCM-R, exhibit antioxidant and anti-inflammatory activities that could be applied as new and innovative natural formulations for the treatment of chronic inflammatory diseases.

In Vitro Cytotoxic Activity of African Plants: A Review.

In African countries, cancer not only is a growing problem, but also a challenge because available funding and resources are limited. Therefore, African medicinal plants play a significant role in folk medicine and some of them are traditionally used for the treatment of cancer. The high mortality rate and adverse effects associated with cancer treatments have encouraged the search for novel plant-based drugs, thus, some African plants have been studied in recent years as a source of molecules with proven cytotoxicity. This review aims to discuss the cytotoxic activity, in vitro, of African plant crude extracts against cancer cell lines. For the period covered by this review (2017–2021) twenty-three articles were found and analyzed, which included a total of 105 plants, where the main cell lines used were those of breast cancer (MCF-7 and MDA-MBA-231) and colorectal cancer (HCT-116 and Caco-2), which are among the most prevalent cancers in Africa. In these studies, the plant crude extracts were obtained using different solvents, such as ethanol, methanol, or water, with variable results and IC50 values ranging from <20 µg/mL to >200 µg/mL. Water is the preferred solvent for most healers in African countries, however, in some studies, the aqueous extracts were the least potent. Apoptosis and the induction of cell cycle arrest may explain the cytotoxic activity seen in many of the plant extracts studied. Considering that the criteria of cytotoxicity activity for the crude extracts, as established by the American National Cancer Institute (NCI), is an IC50 < 30 μg/mL, we conclude that many extracts from the African flora could be a promising source of cytotoxic agents.

THE IMPORTANCE OF SAFFRON MEDICINAL PLANT IN FOLK MEDICINE

This article discusses the saffron medicinal plant, its occurrence, history, pharmacological effects and role in folk medicine.

English

As typical arid vegetation, Calycotome villosa is an annual herb playing an important role in folk medicine. In this research, the influences of temperature and salinity on germination of C. villosa seeds gotten from southern Tunisia were investigated. The germination responses of the seeds in total darkness were determined over an extensive array of temperatures (5, 10, 15, 20, 25, 30, 35 and 40&deg;C) as well as salinities (0, 50, 100, 150, 200, 250 and 300 mM NaCl). Seeds of C. villosa were able to germinate at temperatures between 5 and 40&deg;C. Temperatures between 20 and 25&deg;C seemed favorable to germinate these species. The minimum temperature beyond which no germination is expected was 0&deg;C. Utmost germination percent were gotten in non-saline situations as well as arise in NaCl absorptions&nbsp; increasing&nbsp; repressed germination of seed. The rate of growth reduced with arises in salinity on all temperatures. Salt stress decreased both the percentage and the rate of germination. Percent of germination reduced with growing salinity and sternly restricted at 250 and 300 mM. Findings from this research might function as valuable information for C. villosa habitat establishment and renovation plans. Key words: Calycotome villosa, germination, salinity, temperature, Tunisia.

HPLC-ESI-MS ANALYSIS OF SOME BIOACTIVE SUBSTANCES IN TWO YEMENI MEDICINAL PLANTS

Plants have abundant bioactive components and play an important role in folk medicine, owing to their health benefits in the treatment of many diseases, partially due to the secondary metabolite compositions. Nonetheless, detailed information on these substances is still limited. The recent work was aimed at investigating the bioactive substances of two Yemeni medicinal plants (i.e. Plectranthus asirensis and Plectranthus amboinicus) using reversed-phase high-performance liquid chromatography-electrospray ionization-mass spectrometry in a positive ionization mode. The proposed method provided a tentative identification of several constituents such as alkaloids, fatty acids, steroids, and terpenoids. The obtained results highlight the importance of studied plants as a promising natural source of bioactive compounds.

Antimicrobial Activity of Aqueous, Ethanolic Extracts and Essential oil of Black Cumin (Nigella sativa L.)

Most of the bacterial pathogens are resistant to existing synthetic antibacterial agents demanding an increasing effort to seek effective phytochemicals as antibacterial agents against such pathogens. Nigella sativa L. (black cumin) seeds play an important role in folk medicine and some of its major constituents are reported to be pharmacologically active. Nigella sativa seed extracts were obtained using maceration extraction by two solvents (water and ethanol). The antibacterial of two extracts and essential oil of seeds were investigated by the agar diffusion method against gram positive bacteria (Staphylococcus aureus, which have been obtained from the urine and stool samples).The Aquoeus extract and essential oil showed varying degree of inhibition.

Comparative DNA profiling, botanical identification and biological evaluation of Gazania longiscapa DC and Gazania rigens L.

Gazania longiscapa DC and Gazania rigens L. are species of cultivated ornamental plant that grow in Egypt. Genus Gazania has a role in folk medicine to prevent toothache; this study presents a comparative investigation of genetic and botanical features of root, rhizome, leaves and flowers of the two Gazania species and comparing their biological activity as analgesic and antiinflammatory as related to their folk medicinal use.The genetic and botanical differences between the two Gazania species are reported for the first time in this study. The results contribute toward validation of the traditional use of Gazania showing that both species are safe for oral administration and they exhibit significant antinociceptive and anti-inflammatory effects in a dose dependent manner.

Plants with topical uses in the Ripollès district (Pyrenees, Catalonia, Iberian Peninsula): Ethnobotanical survey and pharmacological validation in the literature

Ethnopharmacological relevanceThe skin is the main structure that protects the human body from environmental factors and has, in addition, a relevant relationship to people׳s appearance and beauty. Official medicine and cosmetics have shown interest on elaborating products to protect the dermal system, yet the role of folk medicine is highly unknown in this field. Taking this into account, we performed an ethnobotanical study in a Catalan district of the eastern Pyrenees (northeast Iberian Peninsula), with the purpose of assessing popular plant knowledge and use. In this paper, we present exclusively the results on topically-used plants. Additionally, we have performed a thorough literature search in order to validate the uses of plants recorded in well-established pharmacological works. MethodologyA number of 163 informants (57.7% women and 42.3% men, born between 1915 and 1988, with an average age of 71.6 years) were interviewed by means of 104 semi-structured interviews. Voucher specimens were collected, prepared and deposited in the BCN herbarium. ResultsWe collected information on the popular uses implying topical application of 115 plant taxa (three determined at generic level and 112 at specific level), belonging to 92 genera and 51 families. Taxa with use reports higher than 5% included Arnica montana subsp. montana, Hypericum perforatum, Thymus vulgaris, Lilium candidum and Tussilago farfara. The degree of reliability of the results is very high, as indicated by a big number of report uses (1676) and a very high informant consensus factor (0.93 of a maximum of 1). Topical uses of 21 plant taxa with more than 1% of use reports have been validated consulting pharmacological literature. ConclusionsData indicate a high degree of plant knowledge in the studied region regarding dermal conditions, cosmetics and additional affections (such as snake bite). The present study constitutes a good basis for further phytochemical and pharmacological research, which could be of interest in the design of new drugs. Furthermore, the evidence of these folk uses could be the key information in simplified procedures established by the European Union for the registration of herbal medicinal products based on traditionally used plants, reinforcing the already recognized role of ethnobotany in the mentioned applied research and development field.

Holunder - Eine uralte Kulturpflanze, historisch betrachtet von Karl Ritter von Perger

COMMON ELDERBERRY: CULTURAL HISTORY OF AN ANCIENT PLANTFor many centuries, the common elderberry ( SAMBUCUS NIGRA L.) has been a widely known plant in Europe. All parts of the plant (roots, stalk, flowers and especially the ripe blackish berries) play an important role in folk medicine. Especially nowadays, the ripe berries are used in the industrial production of beverages. Apart from this, the cultural history of the common elderberry offers some interesting aspects. In the 19th century, Professor Karl Perger from Vienna carried out several studies in this field with important results. Some of Perger’s findings are cited in this article.

Political Analysis and American Medical Care (Book).

Sociology of Health & IllnessVolume 7, Issue 1 p. 118-138 Free Access Book reviews First published: March 1985 https://doi.org/10.1111/1467-9566.ep10831395AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Book reviewed in this articles: T.R. Marmor, Political Analysis and American Medical Care R. Dingwall, J. M. Eekelaar and T. Murray. The Protection of Children: State Intervention and Family Life M.W. Ross, The Married Homosexual Man: a psychological study A.E. Joseph and D.R. Phillips, Accessibility and Utilisation: Geographical Perspectives on Health Care Delivery J. Braithwaite, Corporate Crime in the Pharmaceutical Industry N. Gevitz, The D.O.'s Osteopathic Medicine in America G.V. Larkin, Occupational Monopoly and Modem Medicine F.G. Bolton, Jr., When Bonding Fails: Clinical Assessment of High-Risk Families J.A. Roth and D.J. Douglas. No Appointment Necessary: The Hospital Emergency Department in the Medical Services World E. Bates, Health Systems and Public Scrutiny D. Blazer and I. Siegler, eds, A Family Approach to Health Care of the Elderly D. Jerrome, ed. Ageing in Modern Society J.A. Macheath, Activity, Health and Fitness in Old Age M.A. Smyer and M. Gatz, eds. Mental Health and Aging. J.L. Ruffini, ed., Advances in Medical Social Science I.K. Zola, Socio-Medical Inquiries: Recollections, Reflections and Reconsiderations J.T. Ziegenfuss, Jr. Patients Rights and Organizational Models: Sociotechnical Systems Research on Mental Health Programs R. Snowden and B. Christian, eds, Patterns and Perceptions of Menstruation S. Golub. ed., Lifting the Curse of Menstruation: A Feminist Appraisal of the Influence of Menstruation on Women's Lives T. Vaskilampi and C. P. MacCormack, eds., Folk Medicine and Health Culture: Role of Folk Medicine in Modern Health Care J. H. Thompson, Spiritual Considerations in the Prevention, Treatment and Cure of Disease Volume7, Issue1March 1985Pages 118-138 RelatedInformation

Folk Medicine and Health Culture: Role of Folk Medicine in Modern Health Care (Book).

Folk Medicine and Health Culture: Role of Folk Medicine in Modern Health Care (Book).

Part IV: The social meaning of medicine in a sectarian community

Abstract The role of folk medicine in the social system of the Black Hebrews of Israel is examined in this paper. Similarities in medical and societal structure are identified and the contributions of medicine to the maintenance of Black Hebrew society are explored. An empirical test of some of the suggested contributions is presented.