Abstract

Most of the bacterial pathogens are resistant to existing synthetic antibacterial agents demanding an increasing effort to seek effective phytochemicals as antibacterial agents against such pathogens. Nigella sativa L. (black cumin) seeds play an important role in folk medicine and some of its major constituents are reported to be pharmacologically active. Nigella sativa seed extracts were obtained using maceration extraction by two solvents (water and ethanol). The antibacterial of two extracts and essential oil of seeds were investigated by the agar diffusion method against gram positive bacteria (Staphylococcus aureus, which have been obtained from the urine and stool samples).The Aquoeus extract and essential oil showed varying degree of inhibition.

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