For 5G communications, An different types Antennas are plays major role to minimize mutual couplings and here MIMO is important technology which uses patch antenna’s. Where the existing design focuses only on frequency reconfiguration, but it does not take advantage of the entire frequency and power spectrum. Therefore, the honeycomb-shaped Metamaterial cells used in the suggested antenna design serve as a superstrate for micro-strip patch antennas with a extensive range of actual negative permittivity and permeability, as well as a refractive index feature. Also, to reduce mutual coupling in current printed and other antennas. A metamaterial superstrate-based micro-strip antenna with RF MEMS Varactor diode switching is proposed in this paper. Based on a micro-strip antenna, metamaterials in the shape of circular and hexagonal arrays are employed as the superstrate. Also, the superstrate layers serve as a random, providing strength to the entire structure while also improving other antenna metrics such as gain and bandwidth. The design outputs for several metamaterial superstrates in terms of reflection coefficient (S11), gain, and bandwidth are compared by adding varactor diode switches to the metamaterial superstrate, which also allows for frequency reconfiguration. As a result, the suggested antenna was designed to reduce mutual coupling and improve system performance in 5G technology, specifically in mm-wave applications. The obtained results for metamaterial superstrate designs demonstrate high bandwidth and gain behavior.