Relevance The relevance of conducting research in this area is due to the fact that, nowadays burnout syndrome and suicidal mood are observed among a larger number of teenagers, which causes an increase in the level of mental disorders and fatal outcomes by committing suicide among young people. These problems include a complex of special mental disorders.Purpose. The key goal of this article is to highlight the methods and preventive measures of psychological guidance that will reduce the level of occurrence of these problems. The main task is to reveal the concept of emotional burnout and suicidal mood and to identify factors that contribute to the spread of these phenomena.Methodology. Among the methodological approaches thanks to which the main tasks were achieved, it is worth noting the systematic approach, person-oriented, competence-based, informational, activity-based approaches.Results. In the course of this research, problems were identified that lead to the spread of emotional burnout and suicidal moods among students and pupils. It also shows the features of conducting psychological prevention activities with students. It was proven that during the formation of the syndrome of emotional burnout and suicidal moods in students, indicators of emotional detachment, emotional and moral disorientation, experiencing psycho-traumatic circumstances and inadequate emotional and selective response increase. Methodical recommendations aimed at preventing these syndromes were also developed. The article revealed the general principles of the problem of suicidal behaviour, as well as the main signs of suicidal tendencies of teenagers.Conclusions. The practical value of the considered main components of socio-pedagogical prevention and the analysed main methods from a psychologist to prevent the problem of suicide in adolescence will contribute to reducing the occurrence of these phenomena.