The paper presents a digital model of psychophysiological support for students, organized at various sites of the university. The digital model of psychophysiological support includes a set of procedures and activities aimed at ensuring the impact and support of health indicators, biological functions of homeostasis, and the psychophysiological well-being of students. Among the components of the digital model is the innovative project “Online Curator”, which contains a step-by-step description of the sequence of pedagogical actions of curators of student groups, which are based on the constantly updated information resource “Electronic methodological library”. Pedagogical actions are carried out by curators based on the results of annual monitoring and identification of risk groups among the students. Typical problems of students identified during testing in 2021 were problems of the emotional and personal sphere; communication problems; intrapersonal problems and difficulties of adaptation. The resource “Electronic methodological library” described in the paper is an original bank of methodological information designed to improve the psychological and pedagogical competence of curators and to directly organize a variety of extracurricular work with students. The inclusion of the curator’s figure in collective and individual activities for the psychological support of students using IS resources allows him to effectively carry out socializing, preventive, regulatory functions, providing effective support for the psychological well-being of students.