Pandu Roga Research Articles

A critical review on usage of Ghrita in Pandu

According to Ayurveda, human body is made up from Saptdhatu, Tridosha and Trimal. These are the main functional unit which maintains equilibrium in body. Agni plays most important role in metabolism of body. With the help of Agni, food is converted into absorbable form and also it forms and nourishes Saptdhatu in progressive manner continuously. Any type of disequilibrium in the process, gives rise to diseases like Pandu, Grahani, Kushtha etc. Pandu Roga is disease entity described in Ayurvedic literature which is characterized as pallor complexion of the skin of the diseased person. Pandu is widely described in various Ayurvedic texts as an independent disease and also as associated symptom in many other diseases. The general treatment of Pandu is Snehana, Shodhana, Shamana with herbo-mineral combinations along with dietary modifications. There is specific mention of internal oleation before Shodhana Chikitsa is advised which marks its importance in treatment. Ghritpan is considered best for ignition of Jatharagni as well as Dhatvagni and it also has properties like Jivaniya, Rasayana etc. Ghritapan opposes the etiology of Pandu at level of constitution and diet. In Pandu Chikitsa Adhyay, various medicated Ghrita are described. This present study critically reviews role of Ghritapan in Pandu and different combination of medicated Ghrita described in Pandu Chikitsa Adhyay by Acharya Charaka along with its specific indications.

A Case Report on Ayurvedic Management of Kamala

Kamala or Jaundice is a disease caused due to the dysfunction of liver. Jaundice is also known to be icterus. This is a condition where, skin, congenctival membranes, and other mucous membranes are yellowish pigmented, due to the increased levels of bilirubin in the blood. A concentration of bilirubin higher than 1.8 mg/dl leads to jaundice. It results from the Obstruction of the bile duct or loss of bile producing liver cells. The word “Kaman” means “Itcha” or desire and “Lati” means to diminish. So,Kamala is a disease where, your desire for food,dailyactivities etc are diminished1 . It is a common disorder seen in both urban and rural areas with poor hygiene and sanitation. Pandu Roga is said to be a Nidanarthakara Vyadhi for Kamala.When Pandu Roga is not treated properly it can lead to Kamala. Thus Kamala can also be considered as an effect of untreated Pandu Roga.

Effect of Amalakyavaleha in the Management of Pandu Roga w.s.r. to Iron Deficiency Anemia in Children

Anemia is a prevalent issue among children, characterized by a deficiency in red blood cells or hemoglobin. The primary causes, such as iron deficiency is the most common nutritional deficiency anemia, are often straightforward to address. In Ayurveda, it is correlated to Pandu Roga based on similarities in clinical features and offers various herbal remedies and dietary guidelines, known as Pathya Palan, specifically targeting anemia. It means the disease condition in which the skin of the person is discolored like Haridra or greenish tinge and other peculiar signs and symptoms include Hridayaspandanam, Roukshyam, Swedabhava, Shrama and its consequences. It is not a disease entity as such but is the manifestation of different diseases. There is pallor on the skin due to a deficiency of Rakta Dhatu (blood tissue) either in the form of hemoglobin and or red blood cells (RBCs). This study aimed to evaluate the effectiveness of Amalakayavleha and Pathya Palan in managing anemia. The study was conducted at the OPD of Balroga, Rajiv Gandhi Ayurvedic College and Hospital Paprola Dist. Kangra HP. The method involved assessing patients before and after treatment with a 30-day follow-up period. The results indicated that Amalakyavaleha and Pathya Palan were indeed effective in managing anemia in children.

Efficacy of Vidangadi lauha in the management of Pandu roga (~iron deficiency anemia) in adolescent girls

Introduction: Pandu roga can be correlated to Iron Deficiency Anemia (IDA) in the modern context. Adolescent girls are at high risk of IDA due to the high requirement of iron, low intake of nutrients, and blood loss during menses. Iron and folic acid are the drugs of choice for IDA, but it has some side effects such as stomach pain and constipation. Considering this, in the present study efficacy of Vidangadi lauha was compared with that of iron and folic acid as supplements. Materials and Methods: Adolescent girls aged 10–16 years were screened for the signs and symptoms of Pandu roga and those who were coming under the inclusion criteria for IDA were randomly arranged into two groups. The first group (Group A) was given 10 ml syrup of Vidangadi lauha once daily; while iron and folic acid tablets were given to the control group (Group B) as per the weekly iron-folic acid supplementation schedule for 3 months. For the assessment of therapy clinical features such as Panduta, Daurabalya, and Rukshata and hematological parameters were assessed before and after treatment. Results: On comparing Group A and Group B, the hematological parameters including hemoglobin show nonsignificant results. The difference in subjective parameters was also found statistically insignificant. Conclusion: Statistically, Vidangadi lauha and Iron and folic acid both showed improvement in hematological as well as clinical parameters. However, the formulation Vidangadi lauha is still preferred over iron and folic acid due to its holistic mode of action over Agni (~digestive and metabolic capacity) and the metabolic system of the body with no side effects.

Mandoor Shodhana - A Bird Eye Review

Mandoor (Iron Oxide) is important in Rasashastra as a Dravya from Upadhatu Varg. It is widely used in Ayurveda therapeutics for the treatment of Pandu Roga, Kamala Roga, Rajakshaya and Raktakshaya. Mandoor is found buried inside the earth’s land and is said to be of mineral origin. Thus, it becomes important to get rid of physical and chemical impurities in Mandoor and make it potent for using it in therapeutics. To serve the necessity, Shodhana procedure is mentioned in classical texts of Ayurveda. The physical and chemical changes occurring during Shodhana make Mandoor suitable for the therapeutic use. In the classical texts of Ayurveda and Rasashastra numerous Shodhana procedures for Mandoor are found mentioned. So here an attempt was made to review various Shodhana procedures for Mandoor. In this context eighteen Vishesh Shodhana methods and a Samanya Shodhana found mentioned in different texts. A thorough review was carried out for the Shodhana procedures.

Integrative Management of Severe Case of Anaemia (Pittaj Pandu) with Ayurveda and Contemporary Medicine - A Case Report

Anemia is described as a reduction in the proportion of the red blood cells and Hemoglobin. Anemia is an extremely common disease affecting up to one-third of the global population. In many cases, it is asymptomatic and requires no management but, if it undiagnosed or left untreated for a prolonged period of time can lead to multiorgan failure and can even death. Anaemia in Ayurveda is corelated with Pandu. Pandu Roga is said to be Rasa Pradoshaja. Vyadhi. Pandutha means Pallor which is the characteristic feature of all five varieties of Pandu Roga. The general symptoms of Pandu Roga are Pandutha (Pallor), Shrama (Fatigue), Shwasa (Breathlessness), Arohana Ayasa (Exertional Dyspnea), Hridrava (Palpitations) etc. All these symptoms closely resembles with Anaemia. In this present case study, a 49 year male patient presented with the symptoms of Pandu and was treated successfully with the help of Ayurvedic Medications. The signs and symptoms along with Haemoglobin, MCV, MCH, MCHC, were assessed before and after treatment. There was significant improvement observed after the treatment.

A literary review on Ayurveda perspective of Pandu in Kaumarabhritya

In traditional science of Indian medical system, Childhood age is described as Kaumaravastha. The basic feature of this age group is to increase immunity, physical & mental strength, management of nutritional supply & control of prevalence of disease in of growing children. Kaumarbhritya not only to help paediatric disease but also describe dietary & daily life routine for paediatric care. The Pandu is one of the common diseases of childhood as early growing life which resembles Anaemia as per modern science. The disease involves vitiation of Dhatus by Pitta predominant Tridosha, which leads to deficiency of Blood (Rakta) Fat (Meda) & Ojas.[2] The condition is associated with laxity (Saithilya) of Dhatus, heaviness (Gaurava). Other predominant features are like diminish Varna (Complexion), Vala (Strength) & Sneha (Smoothness) of the body. There are certain premonitory symptoms which indicate chances of Pandu like Hrudaya Spandana (Palpitation), Roukshya (Dryness), Swedabhava (Loss of sweating) & Shrama (tiredness).[4] The Pandu may arise due to Sevan of Kshara, Amla, Lavana, Asatmya Bhojana. Hence Ayurveda recommended to take Satmya Bhojana & all of the foods which increase the amount of blood. The foods like Kharjura, Kismis, Apple, Pomegranate should be given. The drugs to be used in child should have Madhura Rasa.There are various Ayurveda formulation also available for the management of Pandu such as Navayasa Choorna. Samsodhana Karma also indicated for the management of Pandu Roga. This Article described various Ayurveda perspective of Pandu Roga in children.

A Clinical Study to Evaluate the Efficacy of Gudanagaradi Gutika in Pandu Roga with Special Reference to Iron Deficiency Anemia - A Study Protocol

A Clinical Study to Evaluate the Efficacy of Gudanagaradi Gutika in Pandu Roga with Special Reference to Iron Deficiency Anemia - A Study Protocol

A Conceptual Study on the Role of Amalaki Avleha in Pandu roga

A Conceptual Study on the Role of Amalaki Avleha in Pandu roga

A Bird’s Eye View on Ojakshaya with Special Reference to Pandu(Anemia)

It is considered that Ojas is a constituent that embodies the ultimate essence of each and every one of the body's Dhatus, or tissue elements. It is one of the Pranayatanas, or the "seat of life." Ojas is also regarded as the live, luminous energy that resides within the human body. Every bodily component needs it to function efficiently. Both physiological and psychological elements have an impact on it. The classical Ayurveda text describes Ojakshaya as one of the Ojavikara which may be prevalent in various diseases. Referring to our ancient text, Pandu Roga is a disorder brought on by Oja kshaya in the body. Clinical evaluations of Pandu patients can reveal the presence of Oja kshaya; if this information is kept in mind during treatment, it may prevent the disease from progressing further and leading to problems. The relationship between Oja kshaya and Pandu is discussed in old Ayurvedic texts. The findings indicate that Oja kshaya may be more common in Pandu patients. The goal of this review article is to comprehend Oja and Oja kshaya and how they relate to Pandu..

A case report on the use of Ayurveda in the treatment of Iron Deficiency Anaemia

Among pregnant women and young children, nutritional iron deficiency anaemia is a worldwide public health concern and the leading cause of anaemia. Iron deficiency anaemia is often caused by blood loss or mal-absorption. Iron deficiency anaemia and Pandu Roga are very similar clinical entities. Pitta Pradhan Vyadhi is Pandu Roga. The vitiated Doshas in Pandu Roga cause a disruption in tissue metabolism, which results in Dhatu-Shathilya in all of Dhatu. Paleness is the dominant colour across the body. The Rasavaha and Raktavaha Srotasas play a significant role in the development of Pandu. In this case study, we see a 22-year-old female patient with iron deficiency anaemia who, after a month of treatment with Ayurvedic formulations in the Pandu Roga line of treatment and iron-rich dietary supplements, experienced a dramatic improvement in her symptoms (less swelling, no pallor, increased energy, decreased palpitation, and hair loss of 10 strands per day) and an increase in her haemoglobin level (from 8.6g/dl to 12.7g/dl) at a very rapid pace. The Samprapti of Pandu Roga may be broken with the aid of the formulas. Iron deficiency anaemia (Pandu) may be effectively treated with Ayurvedic medication.

AYURVEDIC INTERVENTION IN THE MANAGEMENT OF PANDU ROGA (DIMORPHIC ANAEMIA)

Pandu Roga is an Ayurvedic ailment clinically comparable to many types of Anaemia. This study was done to establish the effect of Ayurvedic management on the patient of Pandu Roga (Dimorphic Anaemia). In the IPD, Arogyashala Rugnalaya, Nashik, from 08/01/2022 to 17/01/2022, A 69-year Male patient, suffering from Pandu Roga (Dimorphic Anaemia) was treated with Ayurvedic management. Shamana Chikitsa (ayurvedic medicinal treatment) And Virechana Karma (Therapeutic Purgation) were administered. The patient felt a significant increase in Hb g% and other hematological investigations. Symptoms were assessed as per the criteria of assessment, and improvement was seen in symptoms. Panduta (Pallor) 75%, Daurbalya (General weakness) 75%, Ayasaja Shwasa (Dyspnoea on exertion) 66.66%, Pindikodveshtana (Leg cramps) 50%, Nidraluta (Sleepiness) 50%, Shiroruk (Headache)100%, Bhrama (Giddiness)0%, Sadana (Fatigue) 66.66%, Gatra Shoola (Body aches) 66.66%, Agnimandya (Impaired appetite) 66.66%, Aruchi (Anorexia) 66.66%. This case study demonstrates that Ayurvedic management was significant in Pandu Roga (Dimorphic Anaemia).

A clinical comparative study of Patolakaturohinyadi Kashaya and Trayantyadi Kashaya in Koshtashakhashrita Kamala w.s.r. to Hepatocellular Jaundice

In our Samhita, Kamala Vyadhi is briefly described. Kamala is a Pittaja Nanatmaja Vyadhi as well as Raktapradoshaja Vyadhi. Charaka has considered Kamala as advanced stage of Pandu Roga. Sushruta and Vagbhata has considered Kamala as a separate disease and Sushruta also told it is due to further complications of Pandu Roga, Kamala can be compared with Jaundice (Hepatocellular Jaundice) in contemporary science. Contemporary science has limitations in treating Kamala Vyadhi but Ayurvedic literature clearly explained pathology and treatment of Kamala Vyadhi in detail.

Unveiling the Mode of Action of Dravya Vikalpa

Shodhana-shamana is one of the treatment classifications in Ayurveda. Medicines for Shodhana can be administered in single drug or combination form. The explanation regarding formulations has been dealt in Ayurveda. Though single drugs have been indicated in various disorders, they may fail to target every stage of disease and may therefore fail in treatment. Thus, the permutation and combination of drugs can act efficiently and target every stage of disease. In the Charaka Samhita Chikitsasthana, shodhana yogas are briefly described for specific ailments, however in the Kalpasthana, dravyavikalpa are extensively explained for shodhana. It is difficult to understand choice of dravyavikalpa as there is no direct description on mode and site of action of yogas mentioned. Hence there is a need for proper understanding of the mode and site of action of various dravyavikalpa. Understanding a specific combination and its kalpana helps one understand how medicines are targeted at vitiated doshas and sthanasamshraya. To illustrate the same, Dravyavikalpa for panduroga mentioned in Charaka Samhita Kalpasthana has been taken as an example. In this study an effort will be made to analyze mode and site of action of Dravyavikalpa mentioned in Charaka Samhita Kalpasthana.
 Keywords: Dravyavikalpa, kalpana vishesha, pandu roga

TO EVALUATE THE EFFICACY OF MUDGA MASURA ADAKI YUSHA AS PATHYA IN PANDU ROGA W.S.R TO IRON DEFICIENCY ANAEMIA – A CLINICAL STUDY

Background &Objective: Pandu Roga is a Pitta Pradhana Tridosha Vikara associated with Rasa and Raktha Vaha Srotas. It is characterized by Pandu Varnata, Arohana Ayasa, Dourbalya, Bhrama, and Hrudaya Spandhana. Anaemia is the most prevalent Nutritional deficiency disorder in the world, it affects all age groups but the most vulnerable are preschool age children, pregnant women and non-pregnant woman of childbearing age. Anaemia is a condition where haemoglobin concentration of the individuals falls below the lower limit of the normal range for the age and sex of the individual. Its common clinical features include pallor, exertional dyspnoea, tiredness, and giddiness, and can be correlated with Pandu Roga. Methods: An Interventional Single Arm Clinical Study conducted in 30 subjects for a period of 30 days. Clinical features and Hematological pa-rameters were documented before and after the treatment. Observations were analyzed and findings were evalu-ated by using Software stigma STAT-3 and statistical analysis done by Wilcoxon signed rank test and paired t test. Results: The study shows that Mudga Masura Adaki Yusha have significant effect in clinical features and Haematological parameters significantly. The results obtained were found to be statistically significant at p<0.001 except for Blood picture and RBC shows p=1.000 and p=0.161 respectively. Conclusion: Mudga Masura Adaki Yusha has significant effect in Pandu Roga.

Comparative efficiency testing of Gudharitaki Awaleha in Pandu Roga (Iron Deficiency Anemia) and Kitchen Garden's Parasbag (dietary supplement)

Background : Panduroga is a pitta-dominant Raktapradoshaja vyadhi. The similarity of the symptoms makes iron deficiency anemia a possibility. A diet deficient in iron-rich foods can lead to iron deficiency anemia related to inadequate dietary iron consumption. Fruits and cruciferous vegetables have the highest concentrations of vitamins and minerals. One of the easiest ways to guarantee that everyone has access to a balanced diet with appropriate micronutrients is to grow a range of foods in the kitchen garden. Aim and objectives- Comparing the efficacy of nutritional supplements from Kitchen Garden (Parasbag) and Gudaharitaki Awaleha is the goal of this study, which is being carried out in collaboration with Mission Samriddhi (MS). Methodology- A total of 60 patients were chosen, divided equally into two groups. While group B patients had 90 days of treatment with Gudaharitaki Awaleha, group A patients also received nutritional supplements from the (Parasbag) Kitchen Garden. Prior to and following treatment, subjective and objective criteria were evaluated. Conclusion and Discussion Both groups' subjective and objective criteria showed a significant improvement. But more patients in group A than group B showed signs of improvement. Conclusion- Because organically cultivated vegetables and fruits are rich in nutrients that aid in the avoidance of nutritional inadequacies, nutritional supplements derived from Kitchen Garden and Gudharitaki Awaleha enhance hemoglobin percentage.

An ayurvedic management of pandu roga with special reference to iron deficiency anaemia: A case study

Anaemia is common micronutrients disease affects health status of very large population of whole world. Iron deficiency is the most common causes of Anaemia. Ayurveda described Pandu Roga which correlated with Anaemia. Ayurveda mentioned causes, symptoms and treatments of Pandu. The Pandu Roga involves lack of haemoglobin due to poor intake of iron through dietary sources, poor absorption and digestive problems may also leads Anaemia.

MANAGEMENT OF PANDU ROGA AS PER AYURVEDIC PRINCIPLES - A CASE STUDY

Pandu roga is elaborately discussed in various Ayurvedic Classics. Based on the clinical manifestations, it can be closely correlated with Iron deficiency Anaemia. It is a condition in which the number of red blood cells or Haemoglobin concentration within them is lower than normal. Various causes may lead to these conditions- poor dietary intake , chronic blood loss, chronic illness, excessive indulgence in substances which hampers Iron absorption like tea, coffee etc. In Modern medical science it is treated with iron rich diet and iron supplements which is mostly associated with certain side effects like Gastric irritation, constipation, hypersensitivity reactions to drugs etc. Materials & Methods- Three medicines Punarnava Mandur, Arogyavardhini vati and Kumariasava were selected to treat a patient of pandu roga. Case Report - A 36-year female patient came with complaints of weakness, anorexia, bodyache, paleness of skin, leg cramps and haemoglobin level of 7.8gm/dl. She was relieved from the symptoms and a raise in haemoglobin level (11.2gm/dl) after treatment. She was treated for 2 months with a two follow, ups one after 15 days and another after 40days. Discussion- Pandu roga can be effectively managed by Ayurvedic haematinic drugs, which are palatable, economically feasible and does not affect the feeling of well-being of the patient. In this study, the follow ups showed gradual improvement in the condition. Conclusion- Ayurvedic medicines have great potential in treating deficiency conditions as established in the study.

Mode of Action of Trikatu Ghrita Yukt Swarnabhasma in Pandu Roga (Anaemia)

Pandu roga, an ancient Ayurvedic term used to describe a specific disease, has been recognized and discussed by various Ayurvedic scholars. According to their teachings, Pandu roga is considered a type of Rasa pradoshaj vikara, with Pitta dosha playing a prominent role in its manifestation. The key characteristic of this disease is Panduthwa, or Pallor, which exhibits clinical features similar to modern-day Anaemia .A condition in modern medicine, involves a deficiency in red blood cells or hemoglobin percentage due to decreased production. It is often associated with poor nutrition and overall health. The problem is commonly observed in low birth weight infants, overweight children who lack energy for physical activity, school-going children, adolescents, and pregnant women. In traditional Ayurvedic medicine, there are various formulations suggested for managing Anaemia, one of which is Trikatu Ghrita Yukt Swarnabhasma. This herbal preparation contains Trikatu, a combination of three spices - Shunthi (Zingiber officinale), Marich (Piper nigrum), and Pippali (Piper longum). These spices are renowned for their digestive and metabolic properties. Additionally, Swarnabhasma, derived from gold, has been utilized in Ayurveda for its rejuvenating and tonic effect.

A Clinical Study to Evaluate the Efficacy of Drakshadi Avaleha in the Management of Pandu Roga

A Clinical Study to Evaluate the Efficacy of Drakshadi Avaleha in the Management of Pandu Roga