The residue number system is widely used in applications such as communication systems, cryptography, digital filters, digital signal processors, fault-tolerant detection, and so on. This paper proposes a multifunction modulo (2n ± 1) multiplier based on the radix-4 Booth encoding scheme that can operate both modulo (2n − 1) and modulo (2n + 1) multipliers using the same hardware structure with only one control signal. A novel modulo (2n ± 1) multiplier based on radix-4 Booth encoding is proposed that can achieve superior performance, with low power, fast operation, high area efficiency, and low area-delay product (ADP) and power-delay product (PDP) compared with similar modified Booth-encoding methods. In addition, by integrating the separate modulo functions of the modulo (2n − 1) multiplier and modulo (2n + 1) multiplier into a single multifunction modulo (2n ± 1) multiplier, the proposed method can save up to 52.59% (n = 16) of hardware area, up to 5.45% (n = 32) of delay time, up to 49.05% (n = 16) of dynamic power, up to 50.92% (n = 32) of ADP, and up to 50.02% (n = 32) of PDP compared with the original separate circuits merged together. Furthermore, the operation ranges of the multiplicand and multiplier of the proposed modulo (2n + 1) multiplier and modulo (2n − 1) multiplier are {0, 2n + 1} and {0, 2n}, respectively, which are wider than for other reported hardware structures. The hardware area, power consumption, and delay time are simulated and verified using Verilog HDL and Xilinx FPGA (Field Programmable Gate Array) Vivado tools. The Xilinx Artix-7 XC7A35T-CSG324-1 FPGA chipset is adopted in the proposed work.