Hydatid Cyst Of Liver Research Articles

Assessment of the Therapeutic Efficacy of Silver Nanoparticles against Secondary Cystic Echinococcosis in BALB/c Mice

Background: Cystic echinococcosis (CE) is a highly prevalent parasitic disease resulting from the hydatid cyst of Echinococcus granulosus. It is also described as a zoonotic disease and considered a neglected tropical infection. Aim: This study assessed the antiparasitic activity of silver nanoparticles (AgNPs), against E. granulosus infection in BALB/c mice. Methods: The green synthesis of AgNPs was accomplished using Zizyphus spina-christi leaves. AgNPs were orally administered to BALB/c mice for acute short-term toxicity evaluation, in doses of 50 mg, 100 mg, 200 mg, and 300 mg/kg, and observations for toxic signs were carried out at 24, 48 h, and 14 days, continuously. Moreover, a total of 20 mice divided into two groups were intraperitoneally administered with 1500 viable protoscoleces for secondary hydatidosis infection. Results: The results showed that AgNPs did not induce any adverse effects or signs and no death, in either group of mice. The histopathological findings in the liver, kidneys, and intestine of the mice administered with AgNPs revealed mild histological effects compared with the control ones. The treated-infected mice showed a change in the appearance of the liver hydatid cysts from hyaline to milky cloudy compared with the untreated infected mice. Conclusion: Biosynthesized AgNPs showed anti-hydatic effects and are suggested as anti-echinococcal cyst treatment.

Laparoscopic Perikystectomy for Hydatid Cyst of the Liver - Advantage and Limitation

Hydatid cyst of the liver still remains a public health problem in endemic countries. It is most often a single cyst in 70% of cases, the progressive complications of which are not rare. Once the positive diagnosis has been established thanks to imaging, it is necessary to carry out the pre-treatment assessment which is essential in the choice of the strategy.we operated on a 49 year old man for a huge hydatid cyst of the left liver of sergment 2 and 3 by laparoscopic approach, we performed an open cyst perikystectomy and treated the resudual cavity safely.

Widespread bilateral lung, liver, and spleen hydatid cysts.

Widespread bilateral lung, liver, and spleen hydatid cysts.

Prospective Study of Feasibility and Outcome of Laparoscopic Cystopericystectomy of Hydatid Cyst of Liver

Prospective Study of Feasibility and Outcome of Laparoscopic Cystopericystectomy of Hydatid Cyst of Liver

Pulmonary Artery Embolism Due to a Ruptured Hepatic Hydatid Cyst Into the Inferior Vena Cava: Clinical and Radiologic Imaging Findings

Background and Aim: Pulmonary embolism because of hydatid cysts is a very uncommon and lethal complication caused by a hydatid heart cyst rupture or a visceral hydatid cyst released into the venous circulation. By utilizing contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI), hydatid pulmonary embolism can be differentiated from other types of pulmonary embolism. MRI mainly displays the cystic nature of lesions better than CT. Pulmonary embolism should be kept in mind in patients with hepatic hydatidosis if there is a sudden occurrence of chest pain and dyspnea, particularly in regions where hydatidosis is endemic. This report aims to present the clinical and radiographic features and discuss the diagnosis and treatment procedure of our patient. Case Presentation: Here, we report a 45-year-old man with pulmonary embolism as a consequence of a ruptured hydatid liver cyst in the inferior vena cava. Multiple intra-arterial pulmonary hydatid cyst emboli originating from a hepatic hydatid cyst ruptured into the hepatic portion of the inferior vena cava were seen in our patient. The patient refused the surgical treatment. Therefore, the patient was treated using Andazol (Albendazole) and Cetirizine hydrochloride. Conclusion: The present case is interesting because pulmonary embolism caused by hydatid cysts is a very uncommon clinical entity. There may be difficulties in diagnosing and treating hydatid cysts, and a definitive diagnosis was possible only by a histopathological examination.

Treatment of hydatid liver cyst: Comparison of open and laparoscopic surgery

Treatment of hydatid liver cyst: Comparison of open and laparoscopic surgery

Role of Radical Surgery in the Treatment of Liver Hydatid Cyst

Cystic echinococcosis (CE), also known as hydatid disease, is a zoonotic disease that occurs when a parasite in the classification of cestoda, Echinococcus granulosus, transmits into the human body at the larval stage. It can be encountered in every stage of life, but mostly between 20-40 years. Approximately 60-70% of cysts develop in the liver mostly in the right lobe. It can grow in size between 1 to 5 cm per year. Usually, drainage and omentopexy are preferred after the cystotomy. Post-operatic biliary fistula occurs in 30-50% of cases. When the cystic diameter is greater than 10 cm, the occurrence rate dramatically increases. In the case of a fistula that lasts longer than 10 days, it is defined as a permanent biliary fistula. A 35-year-old male patient diagnosed with stage 2 cystic echinococcosis developed post-operative cystobiliary fistula, its treatment procedure, and the treatment cost is presented.

Serofibrinous pleural effusion revealing a large hydatid cyst of the liver

Hydatid cyst of the liver remains a serious public health problem in Morocco. It is frequently endemic due to poor environmental sanitation. This benign affection can sometimes cause fatal complications, such as the intrathoracic rupture of a cyst. This is a case of a huge liver hydatid cyst, revealed by serofibrous pleurisy, which is an extremely rare condition. A 9-year-old boy, with no past medical history, was presented to the emergency department for respiratory distress, cough, and right chest pain. The pain was insidious, onset, and progressive. There was no history of fever, hemoptysis or vomica. Physical examination revealed diminished respiratory sounds, with dullness to percussion at the right lung, along-with tenderness in the right hypochondrium area. Chest X-ray film confirmed the presence of right-sided pleural effusion. Thoracoabdominal computed tomography (CT) scan was performed, and it shows a large hydatid cyst of segment VIII of the liver with a huge pleural effusion with no lung lesion. A thoracentesis revealed a yellow fluid. The hydatid cyst was treated by laparotomy and partial excision of the cyst, the diaphragmatic fistula was closed, and the pleural effusion was treated by pleural drainage. After 2 weeks, a chest X-ray showed an encysted pleural effusion, which was later treated by thoracotomy and lung decorticating.

Surgical Treatment of Liver Hydatid Cyst in Elderly Patients: A Propensity Score-Matching Retrospective Cohort Study

Surgical Treatment of Liver Hydatid Cyst in Elderly Patients: A Propensity Score-Matching Retrospective Cohort Study

Radical versus conservative surgical treatment of liver hydatid cysts: A paired comparison analysis

BackgroundThe management of liver hydatid cysts (LHC) is complex and includes surgery, percutaneous drainage, chemotherapy and observation. Broadly, there are two types of surgical treatment for LHC - conservative surgery (CS) and radical surgery (RS). The purpose of this study was to compare the outcome of RS and CS. MethodsData from all patients with LHC treated in Sahloul Hospital, between January 2000 and December 2019, were retrieved. To minimize selection bias, paired comparison analysis (PCA) was performed. ResultsA total of 914 patients were included in this study. RS and CS were performed in 284 and 630 patients, respectively. After PCA, 206 patients were included in each group. The incidence of intraoperative bleeding was significantly higher in the RS group. The overall morbidity was significantly lower in the RS group. Thity-four patients developed recurrence with significantly higher recurrence in CS group. ConclusionRS is associated with fewer postoperative complications and lower recurrence rate compared to CS. RS may be the preferred procedure for LHC if the expertise is available.

Liver Hydatid Cyst with Rupture into Extrahepatic Right Hepatic Duct presenting as Obstructive Jaundice: A Case Report

Liver Hydatid Cyst with Rupture into Extrahepatic Right Hepatic Duct presenting as Obstructive Jaundice: A Case Report

Liver Hydatid Cyst with Rupture into Extrahepatic Right Hepatic Duct presenting as Obstructive Jaundice: A Case Report

Liver Hydatid Cyst with Rupture into Extrahepatic Right Hepatic Duct presenting as Obstructive Jaundice: A Case Report

A successful Laparoscopic surgery for multiple hydatid cysts (7 cysts) of liver : Case Report

Case report : To the best of our knowledge this could be the first report of a successfully performed laparoscopic surgery for female patient having had multiple liver hydatid cysts ( 7 in number) in both lobes of liver. Background: Laparoscopic hydatid surgery ( LHS) was almost gaining acceptance all over the world. But still there are contraindications to this approach of particular are those with multiple cysts ( >3 cysts)1.On reviewing the literature most of the reports of LHS were for patients with solitary hydatid cyst and exceptionally for a maximum of three cysts. Herein an initial effort to expand the application of LHS in managing multiple hydatid cysts of liver (>3) with all the advantages of laparoscopic approach; less pain, good cosmetic results, rapid recovery and less complications

Hepato-Cutaneous Fistula: A rare delayed complication after healed Pyogenic Liver Abscess

Hepato-cutaneous fistula is a rare clinical entity which develops commonly after a complication due to hydatid disease of the liver. Few cases of it have also been reported following percutaneous catheter drainage of liver abscess due to actinomyces,burkholderia pseudomallei and entamoeba histolytica. In case of hydatid cyst of liver, it develops following spontaneous rupture or some intervention. In rest other, it always follows the percutaneous catheter drainage as a part of active underlying diseases process. Here, we report a case of Hepato-cutaneous fistula which develops four weeks after successful treatment of pyogenic liver abscess with complete resolution of abscess cavity.

Is Surgery for Hepatic Echinococcosis Appropriate in a Low-Volume Center?

Background: Cystic echinococcosis is a parasitic disease that develops in endemic areas due to the transmission of Echinococcus granulosus. The liver is the organ most affected. The most frequent symptoms include pain, palpable mass, jaundice, and fever. Diagnosis is based on epidemiologic history, examination, imaging, and serologic tests. Patients and Methods: We conducted a retrospective study of patients with hepatic echinococcosis diagnosed in our center. We collected data from our patients regarding personal history, cyst characteristics, surgery performed, and post-operative complications. Results: Sixteen patients were diagnosed with hepatic echinococcosis, 11 of whom underwent surgery. We found multiple cysts in six patients (37.5%) and a single cyst in 10 (62.5%). In 14 patients the cysts were found only in the right hepatic lobe (87.5%) and in two patients they were found in both lobes (12.5%). Segment 4 was affected in seven cases. The sizes ranged from 2.7 to 20 cm. Endoscopic retrograde cholangiopancreatography was prior to surgery in five patients. The interventions performed were partial cyst-pericystectomies in eight patients, a total cyst-pericystectomy in one case, and drains were placed in two cases of rupture. Post-operative fistulas were evident in five patients, four of which were closed. The fifth, which occurred after emergency surgery for rupture of the cyst, has maintained suppuration. The mean follow-up was 3.5 years. There was no post-operative mortality or recurrence to date. Conclusions: We can state that center without highly specialized hepato-biliary surgery units can assume the surgery of hydatid liver cysts excluding those with well-defined characteristics. The establishment of recommendations for the referral of patients with complex hydatid cysts may help in the optimal management of this pathology.

Results of Minimally Invasive Methods in the Treatment of Liver Hydatid Cyst

Objective: The most common cause of hydatid cyst disease is Echinococcus granulosus. Nowadays, minimally invasive methods such as laparoscopy used in the treatment of hepatic hydatid cyst (HHC). In this study, it is aimed to share the clinical, surgical and postoperative data of patients who underwent laparoscopic surgery with a diagnosis of HHC in our clinic.
 Methods: Data of 105 patients who underwent laparoscopic surgery for HHC between January 2011 and January 2020 were retrospectively analyzed. Patients who were diagnosed with HHC by clinical, indirect hemagglutination test, upper abdominal ultrasonography (USG) and upper abdominal tomography were included in the study. All patients received 10 mg / kg / day albendazole therapy for a total of six weeks, two weeks preoperatively and four weeks postoperatively. Demographic information, clinical characteristics, and the incidence and percentage of complications were analyzed by simple manual calculation.
 Results: 64 (60.95%) of 105 patients who underwent laparoscopic surgery were male and 41 (39.05%) were female. The mean age was 40.6 ± 11.7 years (18-65 age range). The mean cyst diameter was 8.4 cm in size (minimum: 6 cm, maximum: 16 cm). The mean operation time was 55 ± 11.45 minutes (Range: 42 to 70 minute). The mean hospitalization period of the patients was 3.7 days (Range 2 to 7). No recurrence was observed in the 18-month follow-up of the patients.
 Conclusıons: HHC is a common disease in our country, and we think that laparoscopic approach is an effective surgical treatment option in suitable patients and in experienced centers.

Laparoscopic and open operations in the treatment of hepatic echinococcosis. Analysis of short- and long-term results

Aim: to evaluate the short- and long-term outcomes of laparoscopic and open operations in the treatment of hepatic echinococcosis.Materials and methods. The results of laparoscopic and open echinococcectomies performed from 2013 to 2020 were retrospectively studied. Laparoscopic operations were considered the method of choice. Open operations were performed in cases with contraindications to the laparoscopic approach.Results. In total, 57 patients were operated: 47 laparoscopically (including robotic approach in 4 cases), 9 patients underwent open surgery. Radical procedures prevailed among laparoscopic cystectomies: 46 (98%). In the groups of laparoscopic/open cystectomies, partial pericystectomy was performed in 1/3 of patients, subtotal – in 24/4, total – in 13/0, and liver resection – in 9/2 patients, respectively. Laparoscopic procedures were performed mainly for types 1 and 3 of cysts, open procedures – for type 2 (WHO), recurrent and extrahepatic abdominal cysts were indication for open surgery. The frequency of severe complications did not differ between the groups. In the laparoscopic group, 1 (2%) patient died. After laparoscopic cystectomies, the mean (median) hospital stay (8 vs 10 days) and duration of abdominal drainage (10 vs 12 days) were significantly shorter. Relapse occurred only after conservative cystectomies, in one patient in each group.Conclusion. Laparoscopic radical surgery for liver hydatid cysts may be the method of choice if performed in a specialized HPB center. Patient selection criteria should be based on the center's experience in laparoscopic liver surgery.

Acute intraperitoneal rupture of hydatid cysts of the liver: Case series.

Hydatid cyst is a parasitic infection caused mainly by Echinococcus granulosus, which is generally considered benign. However, the hepatic hydatid cyst rupture in the abdominal cavity is a life-threatening incident that requires urgent and multidisciplinary management (emergency physicians, radiologists, anesthetists, and surgeons). This study describes clinical and paraclinical liver hydatid cyst rupture in the peritoneal cavity and details the appropriate treatment.A retrospective review of clinical records of patients hospitalized in Jendouba Hospital for liver hydatid cyst was performed over 8 years, from January 1, 2012 to December 31, 2019. Fifteen cases of liver hydatid cyst complicated with acute rupture into the abdominal cavity were collected out of 625 hydatid liver cysts. All patients underwent emergency laparotomy allowing conservative unroofing procedure associated with peritoneal lavage and external drainage combined with necessary intensive care measures. Clinical features, therapeutic procedures’ details as well as postoperative outcomes are reported. Statistical analysis was performed using the Statistical Package for the Social Sciences for Windows version 20.There were 9 men and 6 women. Patients’ age ranged from 14 to 59 years, with an average of 38 years. Two patients were admitted with abdominal trauma. Acute abdominal pain was the most common complaint. Only 1 patient had an anaphylactic shock. Abdominal ultrasonography and computed tomography scan showed discontinuous cyst wall associated to intraperitoneal fluid in all cases. Intraoperatively, the intraperitoneal effusion was clear in 13 cases and purulent in 2. All patients underwent unroofing procedures associated with intra-operative peritoneal lavage and external drainage. The mean hospital stay was 6.11 days, and the mean follow-up was 19 months. No case of recurrence was reported among the patients.In endemic areas, rupture of a hepatic hydatid cyst in the abdominal cavity should be considered in every case of acute abdominal pain, especially if associated with anaphylaxis signs. Early management starting in the emergency room is needed to ensure good outcome.

Recurrent liver hydatid cyst and port site hydatid cyst in anterior abdominal wall in operated case of laparoscopic cystostomy for liver hydatid cyst: a rare complication

Hydatid disease, or echinococcosis, is a widespread zoonotic parasitic disease caused by a tapeworm that continues to be a clinical and public health problem worldwide, especially in areas where animal husbandry and subsistence farming form an integral part of community life. Location of cyst in different organs of body changes the diagnostic and therapeutic management of the cyst. Four treatment options are currently available: radical surgery, conservative surgery, puncture-aspiration-injection-respiration (PAIR), and antiparasitic medical treatment. Surgery is gold standard for liver hydatid cyst and can be done by open/laparoscopic approach. We are reporting a case of recurrence of liver hydatid cyst with port site anterior abdominal wall hydatid cyst in a 40-year-old female patient operated previously for laparoscopic liver hydatid cystectomy. ­­­Port site hydatid cyst is a rare complication after laparoscopic hydatid cystotomy, but can occur due to lodgement of scolices at port site while removing daughter cyst at port site of laparoscopy.

Single approach to pulmonary and liver hydatid cysts

Back groundHydatid cyst means cyst full of water. It is a parasitic disease caused by larval stage of small tape worm (Taenia Ecchinococcus), causing cyst formation in the liver and in the lung. It is endemic in Iraq. AimTo illustrate how to make use of single surgical approach for the removal of pulmonary and liver Hydatid cysts. Patients and methodsThis is a retrospective study of 75 patients with pulmonary and liver hydatid cysts admitted and surgically managed at the Thoracic and Vascular Department of the Surgical specialties Hospital of the Medical City Teaching Hospital during twenty –year's period from January 2001 to the end of December 2020. ResultsFifty-one patients were female (68%), the remaining 24-patients were male (32%). The youngest patient was two –years old female child, presented with bilateral pulmonary and liver hydatid cysts, while the oldest patient was a 70-years old female. The most common symptoms were cough and dyspnea though some patients are completely asymptomatic. Plain chest X-ray is mandatory in addition to U/S abdomen for accurate localization of the liver Hydatid cyst. CT scan is also used for accurate diagnosis ConclusionSurgery is the primary treatment for the concomitant right pulmonary hydatid cyst and liver, it should be approach by single right thoracotomy incision, and this will offers the best chance of cure.