Three-phase solar inverters can be operated with different modulation strategies such as sinusoidal pulsewidth modulation (SPWM), space vector modulation (SVM), and third-harmonic injection PWM (THIPWM). The selection of the modulation strategy can significantly affect photovoltaic (PV) leakage currents and power losses and compromise the inverter performance. This paper presents a detailed analysis of traditional and modified modulation effects on power semiconductor losses and PV leakage current. The research focuses on a three-phase three-level T-type neutral point clamped (3L-TNPC) solar inverter. A detailed exploration of traditional SPWM and SVM is presented, and a new modified modulation strategy referred to as two-triplen harmonic injection PWM (2THIPWM) is proposed, which can substitute the SVM scheme. Analytical expressions are derived for the proposed 2THIPWM strategy, which can be used for the SVM power-loss approximation. The comparison between 2THIPWM and SPWM shows a conduction-loss difference greater than the 5% normalized range. The modulation strategies are discussed with respect to the PV common mode current signature, and specific design techniques in modulation lead to reduced leakage currents for safety compliance. The theoretical and experimental results obtained using a 3L-TNPC solar inverter are presented to evaluate the modulation strategies and their impact on performance.