One of the biggest challenges in the radiation induced defect science is to understand the complex nature of ion-atom interactions under highly extreme conditions. Here, we report the irradiation induced non-equilibrium defect formation in NiCoCr single phase concentrated solid solution alloy due to (i) the extreme inelastic and (ii) the coupled inelastic and elastic ion-atom interactions. These two conditions are achieved at 5 and 30μm penetration depths along the paths of swift heavy ions (1.542GeV Bi). In general, the irradiation induced damage consists of interstitial-type dislocation loops and vacancy-type stacking fault tetrahedra (SFT). Near the surface (~5μm) where electronic energy loss is dominating (~62.5keVnm−1), the atomic motion primarily results in the formation of SFT. A noticeable increase of dislocation loop formation is observed at 30μm near the maximum energy deposition from elastic interactions (~4.9keVnm−1), as compared to the near surface region (~0.06keVnm−1). Insights on the complex electronic and atomic correlations of extreme energy deposition and dissipation on defect dynamics and structural stability may pave the way for new design principles of radiation–tolerant structural alloys.