Customer expectations for automotive design are increasingly rising, which plays an important role in purchasing behavior. Among them, automobile interior materials are one of the factors that have a significant influence on the overall luxuriousness and satisfaction of automobiles. One of the main affective responses to automotive interior materials is a tactile sensation, and since it is complexly constructed, systematic modeling is required. The current research proposed and tested a structural equation model (SEM) that describes hypothesized relationships among affective variables affecting tactile satisfaction such as luxury, soft, slippery, smooth, bumpy, and thick. A total of 26 samples including natural and synthetic leather using interior material in an automobile was selected as a stimulus to recruit 53 participants. All affective variables were found to affect luxuriousness that subsequently affected tactile satisfaction (path coefficient = 0.652). In particular, perceived softness was a dominant factor affecting tactile luxuriousness in leather (path coefficient = 0.305). The findings of the present study have significant implications for both theory and practice on affective responses and levels that affect tactile satisfaction in leather using automobile interior.