The study sought to investigate the open defecation menace in Ghanaian communities with emphasis on Gambaga and Nalerigu Townships in the North East Region of Ghana. A sample of 70 respondents comprising household heads and Environmental and Sanitation Officers was considered for the study. Purposive and non-probability sampling techniques were used to select the respondents for the study. As a qualitative study, questionnaire, structured interview guide, and personal observation were instruments for data collection. The study revealed among others that the inability of some households to provide toilets in their homes accounted for the state of open defecation in the two townships. Again, some residents in Gambaga and Nalerigu Townships practice open defecation because of the bad odour that emanates from the public toilets leaving bad smell on their entire bodies once they visit the toilets. It was recommended that government, Non-Governmental Organizations, and other philanthropists should assist residents of Gambaga and Nalerigu by assisting them with some credit facilities to empower them to improve on their economic activities especially agriculture to earn enough income for the construction of their household latrines. It is also, recommended that the Municipal Assembly should replace the old public toilets with WC toilets to reduce the amount of odour that emanates from such old pit latrines.