Indian Institute Of Technology Research Articles

Evaluation and comparison of the effect of different chemical surface treatments (monomethyl methacrylate monomer, dichloromethane, and 1:1 v/v 30% trichloromethane and monomethyl methacrylate monomer solvent) on the shear bond strength of acrylic resin teeth to the heat cure denture base resin

Background: Prefabricated acrylic resin teeth for dentures were started in use from 1940. About 26%–33% of denture repairs are the result of debonded teeth which cause distress and increased cost for patients. Taking into consideration the importance of properly bonded teeth to denture bases, this in-vitro study was designed to evaluate and compare the effects of three different chemicals on shear bond strength of cross-linked acrylic resin teeth with heat cure denture base resin. Methodology: This study was carried out in Government Dental College and Hospital, Mumbai, in collaboration with the Indian Institute of Technology, Powai. For the purpose of the study, 100 maxillary right central incisors, made up of heat cure cross-linked acrylic resin (MAARC) were collected. The wax samples were randomly divided according to systematic random sampling and coded into four groups of 25 samples each. The four groups were the control group, the monomethyl methacrylate group, the dichlormethane group and trichloroethane+ monomethyl methacrylate group. Results: The control group had lowest value for shear bond strength ranging from 117 N to 181 N with a mean of 147.8 N, whereas 1:1 mixture of v/v of 30% trichloromethane and monomethyl methacrylate had the highest value ranged from 145 N to 310 N with the mean value of 224.88 N. Among the chemical solvents used, monomethyl methacrylate had the lowest shear bond strength ranging from 120 N to 256 N with the mean value 187.32 N. Conclusion: The study concluded that chemical surface treatment of cross-linked acrylic teeth with 1:1 v/v 30% trichloromethane and monomethyl methacrylate monomer gave the highest strength.

RESEARCH PUBLICATIONS OF PHYSICS AT THE INDIAN INSTITUTE OF SCIENCE, BENGALURU: A SCIENTOMETRICS STUDY

The study attempts to analyse research publications of the Indian Institute of Science, Bengaluru in physics during the period 2010 - 2019. The bibliographic data for this study was extracted from the Web of Science (WoS) Core Collection database. The study analyses the year-wise research publications, types of document, preferred journals for publication, prolific author, h-index, most collaborating institutions and countries, etc. This paper analyses 2593 research papers published by scientists of the Department of Physics, Indian Institute of Science, Bengaluru during the period under the study. The findings indicate that the growth of literature pattern is linear, and journals articles (2421) are the most preferred form of publications by the researchers to communicate their research. Ajay Kumar Sood is found to be the most prolific author and Physical Review B is the most preferred journal. In the most cited publications, only one paper was single-authored and other 19 research papers were multiple-authored. Indian Institute of Technology and Jawaharlal Nehru Centre for Advanced Scientific Research were the leading collaborating institutions (195). The USA, Germany, France, England, and Sweden were the top five most collaborative countries.

Measurement of outgassing rates of Kevlar and S-Glass materials used in torque tubes of High Tc Superconducting (HTS) Motors

Torque tubes in High Temperature Superconducting (HTS) motor transfer torque from superconducting field winding rotor to the room temperature shaft. It should have minimum heat conduction property for minimizing the load on cryo-refrigerator. Generally, these torque tubes are made with stainless steel material because of high strength, very low outgassing and low thermal contraction properties at cryogenic temperatures and vacuum conditions. With recent developments in composite materials, these torque tubes could be made of composites such as Kevlar and S-Glass, which have the required properties like high strength and low thermal conductivity at cryogenic temperatures, but with a reduced weight. Development and testing of torque tubes made of these composites for HTS motor are taken up at Bharat Heavy Electricals Limited (BHEL), Hyderabad in collaboration with Central Institute of Plastics and Engineering Technology (CIPET), Chennai and Indian Institute of Technology (IIT), Kharagpur. As these materials are subjected to vacuum, it is important to measure their outgassing rates under vacuum conditions before manufacturing prototype torque tubes. The present study focusses on the outgassing characteristics of Kevlar and S-Glass, using an Outgassing Measurement System (OMS), developed at IIT Kharagpur. The OMS facility works under vacuum environment, in which the test samples are exposed to vacuum conditions over a sufficient period of time. The outgassing measurements for the composite samples were obtained using pressure-rise technique. These studies are useful to quantify the outgassing rate of composite materials under vacuum conditions and to suggest them for manufacturing composite torque tubes used in HTS motors.

Erratum to: Electrochemical Reduction of Trichlorobiphenyls: Mechanism and Regioselectivity

Affilation of M. V. Sangaranarayanan should read as follows: Department of Chemistry, Indian Institute of Technology, Madras Chennai, 600036 India.

An Empirical Analysis of Entrepreneurship Development Program on Potential Entrepreneurs

Entrepreneurship is the most fascinating component of modern day economy. Lots of training programs related to entrepreneurship emerged due to this. This paper is an attempt to determine the impact of entrepreneurship orientation on potential entrepreneurs. In particular, the study takes into account the perceived benefits before and after the particular program and maps the gap between perceived benefits and actual delivery. A sample of 311 respondents (participants) is collected for the study. The participants were engage in an Entrepreneurship Development Program run by Indian Institute of Technology, New Delhi (India). The paper discusses parameters around which Entrepreneurship Development Program is knitted. A structure schedule is prepared and data is collected on a five point scale in the beginning and at the end of the program. Collected data is fed to SPSS and gap between perceived and actual delivery is identified along with significance. Motivation to start a venture is also observed through structured approach. Necessary descriptive and inferential statistical tools are applied as and when needed. Results are presented trough necessary graphs and tables.

Bibliometric Analysis of Research Publications of Indian Institute of Technology (IIT�s) Based on Published Literature as Reflected in Scopus

The Indian Institutes of technology (IITs) in India account for significant research outcomes from the country. This paper is an attempt to analyze the publications of five older IITs during the period 2007 to 2016 as reflected in SCOPUS, multidisciplinary international database. A total of 10583 research publications have been downloaded and analyzed. This paper tries to give an overview of the research output of the five IITs (IIT Bombay, IIT Kanpur, IIT Kharagpur, IIT Delhi, and IIT Madras) on different parameters like growth rate of research publications, authorship pattern, productivity per capita, degree of collaboration, etc.

Publications by Faculty Members of Humanities and Social Science Departments of IIT Kharagpur : A bibliometric study

<div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><span>This paper evaluates the citation count of article publications in journals by faculty members in the Humanities and Social Science (HSS) Departments of Indian Institute of Technology (IIT) Kharagpur. The publication data is retrieved from the individual bio-sketch and annual reports available in the websites for 17 years from 2000-2016. Web of Science database has been used for counting the citations. Parameters like total publications in journals, most preferred journal for publication, highly cited journals, collaborative status of faculty publications and thereby </span><span>their citation counts, faculty member receiving highest citation are studied. The finding reveals that 623 articles are </span><span>found in total 359 journal. There is an increasing trend in the number of publications over the years. The journal </span><span>named Psychological Studies ranked first with 27 publications of faculties whereas Journal of Business Ethics received highest citations and grabbed the first position amongst the journals. Collaborative researches by three authors received maximum citations. The faculty members are engaged in variant fields of research but the impact is </span><span>higher at national level than that of international level. Sage is found to be the most preferred publisher publishing journal articles of the faculty members from HSS Departments of IIT, Kharagpur. </span></p></div></div></div>

Govindasamy Mugesh

Angewandte Chemie International EditionVolume 58, Issue 3 p. 662-662 Author ProfileFree Access Govindasamy Mugesh First published: 30 August 2018 https://doi.org/10.1002/anie.201809460Citations: 2AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “When I was eighteen I wanted to be a farmer. The natural talent I would like to be gifted with is the ability to learn new languages quickly …” Find out more about Govindasamy Mugesh in his Author Profile. Govindasamy Mugesh The author presented on this page has recently published his 10th article since 2010 in Angewandte Chemie: “Remarkable Effect of Halogen Substitution on the Membrane Transport of Fluorescent Molecules in Living Cells”: H. Ungati, V. Govindaraj, G. Mugesh, Angew. Chem. Int. Ed. 2018, 57, 8989; Angew. Chem. 2018, 130, 9127. The work of G. Mugesh has been featured on the cover of Angewandte Chemie: “Chemistry and Biology in the Biosynthesis and Action of Thyroid Hormones”: S. Mondal, K. Raja, U. Schweizer, G. Mugesh, Angew. Chem. Int. Ed. 2016, 55, 7606; Angew. Chem. 2016, 128, 7734. Date of birth: May 29, 1970 Position: Professor, Indian Institute of Science, Bangalore E-mail: mugesh@iisc.ac.in Homepage: http://ipc.iisc.ac.in/gm.php ORCID: 0000-0002-5389-5309 Education: 1993 MSc, Bharathidasan University, Tiruchirappalli 1998 PhD with Prof. Harkesh B. Singh, Indian Institute of Technology, Bombay 2000–2001 Postdoctoral fellow with Prof. W.-W. du Mont, Technische Universität Braunschweig 2001–2002 Postdoctoral fellow with Prof. K. C. Nicolaou, The Scripps Research Institute, La Jolla Awards: 2011 CRSI Bronze Medal; 2011 AstraZeneca Excellence in Chemistry Award; 2012 Shanti Swarup Bhatnagar Prize; 2015 JC Bose Fellowship, Science and Engineering Research Board; 2017 National Prize for Research on Interfaces of Chemistry and Biology; Current research interests: Artificial enzymes; cellular redox regulation; ferroptosis; fluorescent probes; nitric oxide signaling; thyroid hormones Hobbies: Watching movies, cooking, driving When I was eighteen I wanted to be a farmer. The natural talent I would like to be gifted with is the ability to learn new languages quickly. The biggest challenge facing scientists is too many irrelevant and misleading research problems. My motto is work hard with dedication, serve people, and do not expect anything in return. Looking back over my career, I am satisfied! My favorite saying is “great minds discuss ideas; average minds discuss events; weak minds discuss people”. My favorite time of day is 10.30 am when I take a break and go with my colleagues to the Faculty Club on our beautiful campus for a cup of tea. I advise my students to be honest and help others. My favorite molecule is thyroxine, a simple molecule with amazing functions in the human body. My favorite composer is Isai Gnani Ilaiyaraaja, one of the greatest Indian composers, who wrote music for our every emotion in life. My favorite book is Thirukkural—a 2000-year-old classic Tamil work on ethics, which consists of 1 330 couplets (Kurals), dealing with all aspects of Aram (virtue), Poruḷ (wealth), and Inbam (love). My 5 top papers: 1“An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires”: A. A. Vernekar, D. Sinha, S. Srivastava, P. U. Paramasivam, P. D'Silva, G. Mugesh, Nature Commun. 2014, 5, 5301. (Turning potentially cytotoxic vanadium into a cytoprotective redox modulator in human cells.) 2“A Chemical Model for the Inner-Ring Deiodination of Thyroxine by Iodothyronine Deiodinase”: D. Manna, G. Mugesh, Angew. Chem. Int. Ed. 2010, 49, 9246– 9249; Angew. Chem. 2010, 122, 9432. (Highlights the importance of two biological trace elements, selenium and iodine, in thyroid hormone activation and metabolism.) 3“Antibiotic Resistance: Mono- and Dinuclear Zinc Complexes as Metallo-β-Lactamase Mimics”: A. Tamilselvi, M. Nethaji, G. Mugesh, Chem. Eur. J. 2006, 12, 7797. (The key role played by metal ions in bacterial drug resistance and inactivation of β-lactam antibiotics.) 4“Biomimetic Studies on Anti-Thyroid Drugs and Thyroid Hormone Synthesis”: G. Roy, M. Nethaji, G. Mugesh, J. Am. Chem. Soc. 2004, 126, 2712. (My first paper as an independent researcher. Selenomethimazole can exert its anti-thyroid action by a mechanism different from that of the sulfur analogue.) 5“Synthesis and Structural Characterization of Monomeric Selenolato Complexes of Zinc, Cadmium, and Mercury”: G. Mugesh, H. B. Singh, R. P. Patel, R. J. Butcher, Inorg. Chem. 1998, 37, 2663. (My first ever publication. An intramolecular coordination strategy to prevent the polymerization that is generally observed for Group 12 metal chalcogenolate complexes.) Citing Literature Volume58, Issue3January 14, 2019Pages 662-662 ReferencesRelatedInformation

A LITERATURE REVIEW ON LAND USE LAND COVER CHANGES.

10Jul 2018 A LITERATURE REVIEW ON LAND USE LAND COVER CHANGES. Shaghla Parveen , Jasmeen Basheer and Bushra Praveen. Research Scholar, Department of Geography, Aligarh Muslim University, Aligarh -202002, U.P., INDIA. Reserch Scholar, Department of Economics Aligarh Muslim University, Aligarh -202002, U.P., INDIA. School of Humanities and Social Sciences, Indian Institute of Technology, Indore Madhya Pradesh India.

Alpha-amylase inhibitors from mycelium of an oyster mushroom

The α-Amylase and α-glucosidase are two main enzymes involved in carbohydrate metabolism. This study was aimed at detecting alpha-amylase inhibitory activity from edible mushroom mycelia. Oyster mushroom was collected from a natural source, from Indian Institute of Technology (Banaras Hindu University) campus and was maintained in vitro in mycelial form. Chloroform, acetone, methanol, and water were used separately for extraction of an active constituent from mycelial cells grown, for 7 days, in potato dextrose broth. The extracts were tested for alpha-amylase inhibitory activity. Chloroform, acetone, and methanol extracts were found to have alpha-amylase inhibitory activity, with IC50 values of 1.71, 224, and 383 μg/mL, respectively. Aqueous extract had no enzyme inhibitory activity. The acetone extract inhibited α-amylase non-competitively whereas chloroform extract showed competitive inhibition. Acetone extraction yielded highest total phenolic content (TPC) of 0.524 mM of gallic acid equivalent, whereas chloroform extraction resulted in lowest TPC of 0.006 mM. The HPLC and absorbance maxima of acetone and chloroform extracts suggest that the bioactive component responsible for enzyme inhibition could be glycoproteins in chloroform extract and catechins (flavonoids) in acetone extract. Thus, the mushroom mycelia under study may be exploited for production and purification of a lead compound for the development of the α-amylase inhibitory drug.

An Automated Recommender System for Educational Institute in India

This study aims to suggest a recommender System for undergraduate students who desire to seek admission into engineering courses in different Indian Institute of Technology (IITs) in India. Initially, the focus is to purpose a recommender system for admission into the top 10 IIT on a pilot basis in four common branches such as Electrical Engineering, Computer Science and Engineering, Mechanical Engineering, Civil Engineering. Data were collected from different authentic sources from 2016 to 2018. A model was built to predict the ranks for 2019 for each branch of every IITs. This paper illustrates prediction using Time Series Forecasting and recommendation algorithm using classification techniques. A comparative study of Random Forest Classification and K-Nearest Neighbor classification has been done. Finally, the recommendation algorithm shown reliable results with high accuracy in prediction model. It can be diversify and implement other streams as part of future work.

Web content and design trends of Indian Institute of Technology (IITs) libraries’ website: An evaluation

The present study aims to evaluate and analyse the web contents of Indian Institutes of Technology (IITs) library website/web pages. Survey and observation method was used to collect the primary data from the respective library websites of 19 IITs library websites/web pages where 128 criteria have been designed and data were collected during the month of November, 2016 that was further verified between the periods of 1st March – 15th March, 2017.The study reveals, only four IITs have a library webpage and one has a dedicated page for library. And very less IIT library website/web page have provided the information about the collections, services, value – added services, and Web 2.0 tools link. The evaluation of the websites will help to upgrade the IITs library website which will be useful for other institutions too.

C&EN talks with Claire Komives, antivenom engineer

When Claire Komives, a chemical engineering professor at San Jose State University, began planning for a sabbatical in 2014, she had no clue what research project to pursue. But she knew she wanted to do it in India, a country that she fell in love with while completing a fellowship after earning her Ph.D. During her search for ideas, Komives stumbled on a news story about a protein in opossums that makes the animals immune to snakebites. A Texas-based researcher, Binie V. Lipps, had traced this immunity specifically to the protein’s first 10 or so amino acids, creating a peptide from that sequence and patenting her discovery in 1996. During her sabbatical at the Indian Institute of Technology (IIT) Delhi, Komives picked up where Lipps left off. She developed a low-cost method for synthesizing the peptide. She engineered Escherichia coli to produce a long chain consisting of the first 11

Gundlapalli Venkata Subba Rao (1940–2017)

Professor Gundlapalli Venkata Subba Rao, popularly known as GVS, an excellent solid state chemist-turned materials scientist, was born 12 December 1940 at Bapatla, Andhra Pradesh. He received his Bachelor’s and Master’s degrees from S.V. University, Tirupati and his Ph D degree in solid state chemistry from the Indian Institute of Technology (IIT), Kanpur as one of the earliest students of C. N. R. Rao. GVS then spent nearly three years (1971–74) at the IBM J. Watson Research Centre in New York, USA and later at the Argonne National Laboratory, USA followed by a Humboldt Foundation Fellowship Anorg. Chem. Institut der University Munster and then at University of Bohum, Bohum, West Germany. Subsequently he was invited to take charge of the Materials Research Centre (MSRC) at IIT-Madras, which he developed into an excellent research centre dedicated to materials science. GVS was a pioneer in redefining the field of solid state chemistry. He demanded hard work, creativity and critical thinking from all his students during his tenure at MSRC.

Experimental Analysis of the Thermo-Hydraulic Performance on a Cylindrical Parabolic Concentrating Solar Water Heater with Twisted Tape Inserts in an Absorber Tube

Abstract A twisted tape inserted in an absorber tube may be an excellent option to enhance the performance of a cylindrical parabolic concentrating solar collector (CPC). The present work is an experimental study of the flow and heat transfer with and without twisted tape inserts in the absorber tube of a CPC. Results are presented for mass flow rates of water, ṁ=0.0198–0.0525 kg/s, twist ratio, y=5–10 and Reynolds number, Re=2577.46–6785.55. In the present study, we found that the outlet water temperature, collector efficiency and Nusselt number (Nu) are higher in the twisted tapes as compared to those without the twisted tape inserts in the absorber tube of the CPC. For fixed mass flow rate of water ṁ, the T o and η increased with the decrease in twist ratio, y, and is higher in lower twist ratio, y=5, of the twisted tapes. The whole experiment was performed at the Indian Institute of Technology (ISM) in Dhanbad, India during the months of March–April 2017. Based on the experimental data, the correlations for the Nu and friction factor were also developed.

Kallol Ray

Angewandte Chemie International EditionVolume 57, Issue 28 p. 8366-8366 Author ProfileFree Access Kallol Ray First published: 16 February 2018 https://doi.org/10.1002/anie.201801205AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract When I was eighteen I wanted to be a fighter pilot in the Indian air force. The natural talent I would like to be gifted with is the ability to see the future ...” This and more about Kallol Ray can be found on page 8366. Kallol Ray The author presented on this page has recently published his 10th article in Angewandte Chemie in the last 10 years: “A Highly Reactive Oxoiron(IV) Complex Supported by a Bioinspired N3O Macrocyclic Ligand”: I. Monte Pérez, X Engelmann, Y.-M. Lee, M. Yoo, E. Kumaran, E. R. Farquhar, E. Bill, J. England, W. Nam, M. Swart, K. Ray, Angew. Chem. Int. Ed. 2017, 56, 14384; Angew. Chem. 2017, 129, 14576. The work of K. Ray has been featured on the inside cover of Angewandte Chemie: “Oxidation Reactions with Bioinspired Mononuclear Non-Heme Metal–Oxo Complexes”: X. Engelmann, I. Monte-Pérez, K. Ray, Angew. Chem. Int. Ed. 2016, 55, 7632; Angew. Chem. 2016, 128, 7760. Date of birth: December 13, 1978 Position: Professor of Inorganic Chemistry, Humboldt-Universität zu Berlin E-mail: kallol.ray@chemie.hu-berlin.de Homepage: https://www.chemie.hu-berlin.de/en/forschung-en/ray/ray-en/kallolray ORCID: 0000-0003-2074-8844 Education: 2001 MSc, Indian Institute of Technology, Kanpur 2005 PhD supervised by Prof. Dr. Karl Wieghardt, Ruhr-Universität Bochum and Max Planck Institute (MPI) for Bioinorganic Chemistry, Mülheim an der Ruhr 2005–2006 Postdoctoral position with Prof. Dr. Karl Wieghardt, MPI for Bioinorganic Chemistry 2006–2009 Postdoctoral position with Prof. Dr. Lawrence Que, Jr., University of Minnesota Awards: 2012 Ernst Haage Prize, MPI for Chemical Energy Conversion; 2013 Wöhler–EurJIC Young Investigator Prize; 2015 Carl Duisberg Memorial Award, GDCh; 2016 Heisenberg Professorship, DFG. Current research interests: Bioinspired catalysis; organometallic chemistry; water oxidation reactions; activation of C−H bonds; fuel cells; recyclable energy sources Hobbies: Cricket, soccer, fitness, wine tasting When I was eighteen I wanted to be a fighter pilot in the Indian air force. The natural talent I would like to be gifted with is the ability to see the future. The secret of being a successful scientist is to learn how to deal with criticism in life. My favorite molecule is hopefully yet to be discovered from an unexpected reaction in my laboratory. If I had one year of paid leave I would use the time to teach my kids my mother tongue Bengali. The principal aspect of my personality is impatience. What I appreciate most about my friends is that they accept me with all my flaws. Chemistry is fun because it is sometimes too difficult even for chemists to understand. My favorite drink is a Zombie. In a spare hour, I … wish I had that luxury. My favorite quote is “Don't criticize what you can't understand” (Bob Dylan). My biggest inspiration is my parents. I advise my students to be even (over)confident rather than being insecure in their lives. My 5 top papers: 1“Temperature Dependence of the Catalytic Two- versus Four-Electron Reduction of Dioxygen by a Hexanuclear Cobalt Complex”: I. Monte-Pérez et al., J. Am. Chem. Soc. 2017, 139, 15033. (A deep understanding of the factors that control 2e−/2H+ vs. 4e−/4H+ reductions of dioxygen.) 2“Redox Non–innocence of a N–Heterocyclic Nitrenium Cation Bound to a Nickel–Cyclam Core”: F. Heims, F. F. Pfaff, S.-L. Abram, E. R. Farquhar, M. Bruschi, C. Greco, K. Ray, J. Am. Chem. Soc. 2014, 136, 582. (The coordination chemistry of an N-heterocyclic nitrenium ion to a first-row transition metal and its implication in catalysis.) 3“A High-Valent Heterobimetallic [CuIII(μ-O)2NiIII]2+ Core involving Nucleophilic Oxo Groups”: S. Kundu et al., Angew. Chem. Int. Ed. 2013, 52, 5622; Angew. Chem. 2013, 125, 5732 (Novel reactivity patterns of heterodinuclear bis(μ-oxo) complexes compared to their homodinuclear analogues.) 4“Lewis Acid Trapping of an Elusive Copper–Tosylnitrene Intermediate Using Scandium Triflate”: S. Kundu, E. Miceli, E. Farquhar, F. F. Pfaff, U. Kuhlmann, P. Hildebrandt, B. Braun, C. Greco, K. Ray, J. Am. Chem. Soc. 2012, 134, 14710. (The long-sought reactive intermediate that is believed to be involved in the copper-mediated amination and aziridination reactions was trapped.) 5“An Oxocobalt(IV) Complex Stabilized by Lewis Acid Interactions with Scandium(III) Ions”: F. F. Pfaff et al., Angew. Chem. Int. Ed. 2011, 50, 1711; Angew. Chem. 2011, 123, 1749. (We trapped the elusive intermediate that is postulated to occur in cobalt-mediated oxidation reactions.) Volume57, Issue28July 9, 2018Pages 8366-8366 ReferencesRelatedInformation

Studies on Nitration of Phenol over Solid Acid Catalyst

Progress in Petrochemical Science Studies on Nitration of Phenol over Solid Acid Catalyst Lipika Das1, Koushik Guha Biswas2* and Jayanta Kumar Basu3 1Department of Chemical Engineering, Haldia Institute of Technology, India 2Department of Chemical Engineering, Rajiv Gandhi Institute of Petroleum Technology, India 3Department of Chemical Engineering, Indian Institute of Technology, India *Corresponding author: Koushik Guha Biswas, Department of Chemical Engineering, Rajiv Gandhi Institute of Petroleum Technology, Amethi, Uttar Pradesh, Pin-229304 India Submission: January 01, 2018; Published: February 15, 2018 DOI: 10.31031/PPS.2018.01.000503 ISSN 2637-8035Volume1 Issue1

Magnetic field remote control for memory devices

Physicists at the Indian Institute of Technology (IIT) in Hyderabad have fabricated a 'nonvolatile memory' (NVM) storage device whose 'on' and 'off' states can be remotely controlled by varying the magnetic field1. Their findings may help develop future memory devices operated by magnetic fields. NVM, exhibited by devices such as USB flash drives, MP3 players and digital cameras, is a type of computer memory that can hold saved data even if power is turned off. As present silicon-based devices approach their scaling limits, research is on to develop the next generation of NVM technology that will allow storage of more data at less cost.

Process-machine interactions and a multi-sensor fusion approach to predict surface roughness in cylindrical plunge grinding process

Abrasive finishing processes, such as cylindrical plunge grinding are employed across broad industrial sectors for surface quality assurance. However, uncertainties in the workpiece and wheel states due to the highly dynamic nature of the system are known to adversely affect our ability to predict and assure surface quality. Recent advances in smart manufacturing and sensing technologies offer an opportunity to improve surface quality assurance. Central to the sensing scheme for this is the identification of the physical relationship connecting the measured vibration signals with the surface characteristics. While our experimental studies suggest that vibrations over 700-2000Hz are significant determinants of the surface finish (Ra) in the plunge grinding process, prior models do not capture the effect of high frequency signatures (> 500Hz). To understand the physical origin of these high-frequency signatures, a three degree of freedom lumped mass model of the cylindrical plunge grinding process dynamics was investigated in this paper. The model integrates the random distribution of the abrasive particles forming the wheel topography, the interactions between an elementary abrasive particle and the workpiece surface, and the regenerative relationship between the vibrations of the machine structure and the cutting forces. The model was verified on an industry-scale “next generation precision grinder (NGPG)” testbed at the Indian Institute of Technology, Chennai, India. The experiments were conducted at twelve different plunge rates and data was gathered synchronously from two accelerometers and a powercell integrated with the machine tool. The results suggest that the model accurately captures the changes in the high frequency characteristics with the process parameters. Subsequently, a data-driven random forest model was developed to predict Ra using the features extracted from the measured signals. The model was able to predict Ra over various test conditions to an accuracy of R2>90%. Subsequent statistical analysis also suggests that the vibration frequency component in the 700-2000 Hz range contributes significantly to variations in surface finish Ra.

A Docking Study on Various Secondary Metabolites from W. somnifera on Tetrahydrodipicolinate N-Succinyltransferase Protein Involved in The Lysine Biosysnthesis Pathway in P. aeruginosa

A crucial survival factor for leading pathogen (carrying 40-60% mortality rate) is Tetrahydrodipicolinate NSuccinyltransferase (DAPD EC 2.3.1.117) involves in lysine biosynthesis pathway of P. aeruginosa. Targeting the lysine biosynthesis pathway is a opportunistic and logical site to inhibit the effect of this organism. Withania somnifera, also known as “Indian ginseng”, a reputed herb in ayurvedic medicine, constituting various steroidal lactones (withanolides, withaferins) and saponins which shown various pharmacological activities. We described the docking of 11 secondary metabolites from Withania somnifera into the three dimensional structure of DapD protein of P. aeruginosa using swiss-dock server. Simultaneously, we have checked the ADME values and pharmacokinetics values of these secondary metabolites against the target protein. We have followed the “Lipnski rule of 5” principle and “Molinspiration” tool. Dihydowithaferin, 4-B, Hydroxywithanolide, Withanoloide E, Withanoloide F, Withanoloide D, Withanoloide A) have potential to be used as medicine to treat P.aeruginosa infections. Several known antibiotics also studied along with this approach for comparison purpose. Background/Objectives: Withania somnifera additionally referred to as “Ashwagandha” and “Indian ginseng” is a medicative plant constituting (isopelletierine, anaferine, cuseohygrine, and anahygrine, etc.), hormone lactones (withanolides, withaferins) and saponins., P.aeruginosa is a leading gram negative opportunist infectious agent, carrying a high 40-60% death rate and causes grievous infections in people with compromised immune systems. Tetrahydrodipicolinate N-Succinyltransferase (DAPD Europetwo.3.1.117) potential targets for brand spanking new antibacterial drug medication. Methods/Statistical analysis: The tying up method involves the prediction of matter conformation and orientation (or posing) inside a targeted binding web site. Swiss Dock may be a tying up internet server. All calculations are performed on the server aspect, so for tying up run’s don't need any machine power from the user. The ligands were neutralized and checked for his or her ADME properties victimization computer code Molinspiration obtainable at machine resources for Drug Discovery (CRDD). The secondary metabolites and antibiotics were conjointly subjected to Lipinski Rule of 5 value's on server The Supercomputing Facility for Bioinformatics & machine Biology (SCFBio), Indian Institute of Technology, N. Delhi. Findings: Among the eleven secondary metabolites from Withania somnifera and seven antibiotics we elect for docking, Ciproflaxin, Cephalosporin, Tobramycin, and Azlocillin showing the higher result compare to alternative compounds. Results of ADME properties showed Compounds as 4-B hydroxywithanolide, 2-3 dihydowitaferin A, Withanoloide E,Withanoloide D, Withanoloide A, and Withanoloide F has higher ADME values then the unremarkably used antibiotics (Azlocillin, Ciproflaxin, Ticarcillin, and antibiotic). Results of Lipinski rule of five values are given below in one table. Secondary metabolites like 4-B hydroxywithanolide, 2-3 dihydowitaferin A, Withanoloide E, Withanoloide D, and Withanoloide F showed higher results for Lipinski rule of five compare to antibiotics like Alocillin, Mefoxin, Meropenem, and Tobramycin. Improvements/Applications: Ashwagandha is employed from a few years for several treatments. This analysis additionally stresses the likelihood of this plant to use for cure of an added chronic infection. The experiment shows probabilities to develop a brand new drug.