Index Of Functional Changes Research Articles

Assessment of the Adequacy of Amateur Sports by the Functional Status of Students

Background: In the right dose, physical activity can bring health benefits. Objectives: To assess indicators of health and physical development of students engaged in amateur sports. Materials and methods: The study involved 30 male students aged 23.8 ± 0.3 years. We established their daily energy expenditures, integral indices characterizing their physical development, such as body weight, Pignet, strength, vitality, and Kerdo vegetative indices, endurance rate, circulatory efficiency, and the index of functional changes. We also analyzed cardiovascular system parameters including heart rate, systolic and diastolic blood pressure at rest, after exercise and after exercise recovery. Results of the biochemical blood test taken the next morning after workout were used to evaluate the status of functions and systems of the body. Results: Energy expenditures amounted to 3,665.5 ± 37.3 kcal. Students were physically strong, their functional capabilities of the respiratory system and adaptation to sports (according to the activity of the parasympathetic autonomic nervous system) were found satisfactory while their physical activity was assessed as high (hard work). In the body, catabolic processes prevailed, and the level of cortisol exceeding the norm in 50.0 % of the subjects indicated stress. Inadequacy of physical exercises was evidenced by the index of functional changes (in 57.7 % of the students adaptation was in the state of functional stress); reaction of the cardiovascular system (endurance and heart rates, circulatory efficiency, creatine kinase MB, troponin-1, ALT, and LDH); increased erythropoiesis; hormonal changes (cortisol, testosterone); changes in the metabolism of proteins (total protein, urea, uric acid), fats (total cholesterol, high- and low-density lipoproteins), and hormones (cortisol, testosterone); signs of an early stage of anemia (erythrocytes, total protein, ferritin). Conclusion: The use of the methodology for assessing the functional status of the human body by integral and biochemical criteria during recovery period after exercise enables pre-nosology diagnostics and prevention of health disorders during active sports.

STUDY OF PHYSIOLOGICAL AND PSYCHOLOGICAL INDICES OF UNIVERSITY STUDENTS

Purpose: assessment of functional indices of external respiration, the level of physical health and the general state of the autonomic nervous system of university students. Material: There were examined 192 students aged 18-21 years. All examined were divided into groups depending on gender, age and future profession. Anthropometric indices and parameters of the circulatory system were studied. Spirometer was used to measure the respiratory system functional indices. An express assessment of physical health level was made. Index of functional changes, the Kerdo vegetation index, the orthostatic index, and the Skibinskaya index were calculated. Stange test, Hench test and Martin-Kushelevsky’s test were conducted. Results: The results are showed that the minute blood volume was higher in all examined young girls, whereas in young boys designers and pharmacists aged 17-18 years and 19-21 years, respectively it was lower than due values. Similar data were obtained after the Ruffier test (dynamic load tolerance). The index of vital lung capacity (VC) was significantly lower than due values in all students. The parameters of maximal pulmonary ventilation indicated good functional ability of the external respiration apparatus in young boys. This index was higher than that of young girls and exceeded due values. The adaptation capacities of the student body (index of functional changes (IFI)) were at a satisfactory level. The indices of physical health level of all students had average values. Conclusions: Studies have revealed the most characteristic shifts of cardiorespiratory system indices, which are most expressed in students. Cardiorespiratory system shifts are caused by the influence of a complex of factors: increased academic load; requirements for the professionalization process continuity; performance of various structured activity types, manipulations, a high degree of responsibility. Increased pulse rate and minute blood volume; prevalence of the hyperkinetic type of blood circulation self-regulation at rest; irrational cardiovascular system response to dosed physical load; positive value of the Kerdo vegetation index; decreased ventilatory lung capacity and reserve capacity of cardiorespiratory system; tension of adaptation mechanisms; average level of physical health were recorded in students.

The impact of the labor process severity on the formation of health disorders of protected ground grower

Introduction. The severity of the labor process is one of the leading harmful factors of working conditions in greenhouse vegetable growing. Nevertheless, its influence on the formation of health disorders of vegetable growers has not been sufficiently studied. Material and methods. Physiological, hygienic and epidemiological studies were carried out, which included an assessment of the severity of work in the annual cycle, also the functional state of the cardiorespiratory system and the neuromuscular system in the dynamics of the work shift, the general morbidity of vegetable growers according to registration forms No. 025/y. Results. During the labor activity, vegetable growers were established to be exposed to physical overloads caused by the severity of the labor process (classes 3.2, 3.3) in combination with a heating microclimate (classes 3.1-3.3). By the end of the work shift, there was an increase relative to the initial levels of heart rate (p<0.05), a decrease in systolic and diastolic blood pressure, a reduction of maximum muscle strength (by 3.76-5.28%), and endurance of the muscles of the hands (by 18.5-33.15%). This indicated a decrease in working capacity and an increase in fatigue. A reduction in the Skibinski index (by 21.7%) and an increase in the index of resistance to hypoxia (by 38.9%) indicated a decrease in the body’s reserves of oxygen. Increased working levels of the index of functional changes testify about the tension of adaptation mechanisms and insufficient restoration of the body’s resources by the beginning of the shift. A decrease in the body’s physical condition and adaptive capabilities with an increase in professional experience was revealed (p<0.05). There were established statistically significant direct correlations between the prevalence of diseases of the circulatory system (r=0.6), musculoskeletal system, and connective tissue (r=0.35) with work experience in the profession (p<0.05). Conclusion. The revealed violations of the functional state and health of female vegetable growers result from the influence of physical overload in a heating microclimate. The priority measures for the prevention of health disorders of vegetable growers are to reduce physical overload and thermal effects of the working environment.

Особенности системы кровообращения детей 8–17 лет разной этнической принадлежности, проживающих в условиях Ханты-Мансийского автономного округа – Югры

The research involved 479 schoolchildren living on the territory of the Khanty-Mansi Autonomous Okrug – Yugra (KMAO – Yugra). Two groups were singled out: the Khanty and 1st and 2nd generation descendants of newcomers. The following parameters were studied: blood pressure, heart rate, double product, and index of functional changes; the frequency of deviations from standard values was identified. In addition, the dominant type of circulation was determined. The analysis of the children’s circulatory system parameters revealed some ethnicity-related features. It was established that Khanty children have higher aerobic capacity of the cardiovascular system and lower blood pressure than newcomers’ descendants. Blood pressure deviations from the norm (high blood pressure in girls and arterial hypertension in boys) were statistically more common in newcomers’ descendants. Virtually one in two children had heart rate exceeding the normal values. Moreover, we observed increased stress of the cardiovascular system in the group of newcomers’ descendants (in girls aged 12–15 and boys aged 14–17 years) which was indicated by higher values of double product and index of functional changes. Hyperkinetic type of circulation was predominant in both groups, being, however, more frequent in Khanty children. The revealed features of the cardiovascular system in children of different ethnic groups living in KMAO – Yugra highlight the importance of developing regional and ethnic standards for an objective evaluation of children’s health. For citation: Govorukhina A.A., Kon’kova K.S. Features of the Circulatory System in 8–17-Year-Old Children of Different Ethnic Groups Living in the Khanty-Mansi Autonomous Okrug – Yugra. Journal of Medical and Biological Research, 2021, vol. 9, no. 2, pp. 126–137. DOI: 10.37482/2687-1491-Z050

Health effects of aqua fitness on the body of women of the first mature age

Purpose: to identify the health effects of aquafitness on physiological parameters of women of the first mature age. The following research methods were used to solve the tasks set in the work: theoretical analysis and generalization of data of scientific and methodological literature; pedagogical methods; anthropometric research methods; physiological methods (vital index, strength index, Robinson index, Stange test, Genchi test, Kerdo index, Rufier test, index of functional changes (Kettle index); methods of mathematical statistics. We checked the statistical significance of the difference between the indicators before and after the experiment using nonparametric Wilcoxon criteria (p≤0.05), which were used to establish the shifts of the corresponding indicators. The research was conducted on the basis of the fitness club "Sport Live" in Chernivtsi. The transformation experiment involved 24 women aged 21-31 years. Classes were held in accordance with our comprehensive aqua fitness program, which is designed for 6 months. Class duration is 60-80 minutes, three times a week. The program developed by us included exercises from the arsenal of aqua stretching, hydroshaping, aquadance, aquarism, aqua building, aqua taibo. Results. The data obtained on the somatic health of women aged 21-31 years show a significant improvement in the results (p≤0.05) of anthropometry, the functional state of the cardiovascular, respiratory system, autonomic nervous system, physical condition and performance. During the conversion experiment, the following indicators improved: life index from 45.96 ± 4.69 to 48.88 ± 0.68; power index from 35.80 ± 1.07 to 43.26 ± 0.71; Robinson's index from 85.72 ± 12.34 to 89.63 ± 10.11; barbell samples from 30. 28 ± 10.32 to 37.78 ± 12.34; Genchi samples from 16.48 ± 4.24 to 25.19 ± 4.58; Kerdo index from 5.23 ± 10.16 to 0.86 ± 8.34; Rufier's test from 12.21 ± 4.26 to 8.03 ± 2.14. Conclusions. The effectiveness of the aqua fitness program for women of the first adult age is confirmed by the results of positive changes in body weight, improvement of the cardiovascular and respiratory systems of the body. The proposed program of classes provides optimization of the level of physical, functional and mental condition, solving problems of correction and prevention of functional disorders in health and allows to meet the needs for leisure, recreation and self- improvement of women of the first mature age.

MORPHOFUNCTIONAL CHARACTERISTICS OF ADOLESCENTS AND YOUNG MALES IN COMBAT SPORTS

Aim. The article aims to determine the functional characteristics of the cardiovascular system in adolescents and young males in combat sports depending on their body type. Materials and methods. Adolescents and young males of the yakut population (freestyle wrestlers and boxers) were examined. The indicators of 42 athletes were studied. Anthropometric and somatometric methods were used. The somatotype was determined by Pignet and Rees-Eysenck indices. The cardiovascular system was studied by the index of functional changes. Blood pressure measurements and pulse counts were performed before and after exercise. The following physical activity was proposed: extended arm squats with a frequency of 20 squats in 30 seconds. Statistical processing was carried out using the SPSS 17.0 software package. Parametric and nonparametric methods of statistical analysis were applied. Results. In terms of body mass index, 14.3 % of the surveyed persons had insufficient body weight, 85.7 % – normal body weight. Overweight and obesity in athletes were not detected. Only persons of teenage age had a body weight deficit. It was established that persons with a strong physique according to the Pignet index and a normostenic somatotype according to the Rees-Eysenck index possessed significantly larger reserve and recovery abilities of the cardiovascular system. Conclusion. The obtained morphofunctional characteristics can be taken into account when selecting athletes to achieve higher sports results

мPhysiological Assessment of Miners’ Noise Exposure and Measures for Its Prevention

Introduction: To solve the tasks of preventing occupational diseases in workers of the mining industry, it is important to substantiate physiological indicators of tension of the regulatory systems of the human body under the negative impact of industrial noise and neuro-emotional work intensity and to assess the effectiveness of hearing personal protective equipment (PPE). Our objective was to identify physiological characteristics of adverse functional changes in workers of various professions in the mining industry exposed to the combined effect of occupational noise and work intensity to substantiate the use of hearing protection devices. Materials and methods: We studied indicators of concentration of attention, short-term memory, speed of perception of visual and auditory signals, and the index of functional changes in the circulatory system reflecting negative effects of occupational noise exposure combined with work intensity on the central nervous and cardiovascular systems. We assessed occupational noise exposure by the equivalent sound level on the A-scale of a sound level meter per shift, work intensity, and conducted physiological studies of mining industry employees. Results: In miners, we established a 5.6-fold decrease in concentration of attention from the initial level and a 5.9-fold increase in the index of functional changes in the circulatory system compared with operators of robotic complexes, in which all indicators varied within the physiological norm. The maximum change in the parameters indicates the work tension that was the most pronounced in miners. The same extent of workplace stress was observed in operators of mineral processing plants and engineering and technical staff exposed to similar noise levels (60-70 dB, sometimes exceeding 90 dBA), while the lowest one was observed in the operators of robotic complexes, thus indicating maintenance of a sufficient level of working capacity during the work shift. The estimated miners’ index of functional changes in the circulatory system (2.69±0.08 points) demonstrated the state of functional stress. The individual analysis indicated a significant percentage of people with reduced unsatisfactory adaptation and the state of its failure (3.0±0.05 points) in this very professional group. According to the results of establishing a causal relationship between the increase in the functional tension by indicators of the central nervous system and cardiovascular system and occupational noise levels, emotional stress and adverse shift mode, the workplace stress was justified as a marker of the combined effect of noise and intensity of the work process. Conclusions: A high level of workplace stress accompanied by intensive occupational noise and work intensity factors is an indicator of a decreasing working capacity and development of a prognostically unfavorable functional state of the human body.

THE ASSESSMENT OF EMOTIONAL STRESS UNDER COGNITIVE LOAD IN MALES WITH A DIFFERENT LEVEL OF PHYSICAL ACTIVITY

Background. In view of the continuous increase in the importance of information technologies in all spheres of society, the problem of the effect of significant cognitive loads that accompany information stress becomes extremely urgent. The article presents an analysis of studies (2018–2019) on resistance to cognitive loads in males with different levels of physical activity. Aim. The article aims to evaluate the dynamics of psychophysiological reactions to cognitive load in males with different levels of physical activity. Materials and methods. Regulatory mechanisms were assessed using the index of functional changes. The simulated load consisted in the Gorbov–Schulte table to be made in the conditions of time deficit, increased motivation and interference. Continuous recording of vascular tone, vascular blood flow, heart rate, electrical skin activity was performed. It is established that a different level of physical activity is specifically associated with the adaptation of a person to a significant cognitive load. Results. The dynamics of skin electrical activity, heart rate, vascular tone and vascular blood flow in people with moderate physical activity reflects optimal reactions to load. Conclusion. Persons systematically involved in physical activity in these conditions have a higher adaptive capacity of the vascular part in comparison with professional athletes and people not engaged in physical activity.

FUNCTIONAL STATE OF OMON FIGHTERS BEFORE AND AFTER TRIP

Introduction. The study of the physiological status of representatives of power structures at different stages of service is very relevant.Purpose: a comprehensive assessment of the functional state of the body of OMON fighters before and after a 4-month business trip on perform a special task associated with health and life risks. Materials and methods. 34 OMON fighters of the Komi Republic were examined before the trip and after a 4-month trip to the North Caucasus, where they constantly experienced stress. To assess the functional state of the body, a complex of anthropometric, physiometric, psychophysiological, physiological and biochemical studies was used.Results and its discussion. Before the trip, the fighters showed an increase in the time of the visuomotor reaction, the index of functional changes, the myocardium index, the centralization index, the activity index of regulatory systems, blood pressure indicators and other changes that indicate the activation of free radical oxidation processes, and the appearance in individuals of prenosological and even premorbid conditions. In most of the examined patients, a shift in the autonomic balance was found towards strengthening the sympathetic link in the regulation of heart rhythm. Hypovitaminosis was found in many fighters. After a trip, the functional state deteriorated in most indicators (increased blood pressure, personal anxiety, cholesterol, etc., decreased life index and hemoglobin content, etc.) and the number of people with depleted regulatory systems almost doubled.Conclusion. In general, the body of OMON fighters experiences increased functional stress with signs of obvious stress both before a trip to an area dangerous for health and life, and in the first days after returning to places of permanent residence in the North. In this regard, they need additional health and rehabilitation measures related to optimization of the regime of work and rest, activation of physical education, rationalization of nutrition and strengthening the work on the psychological impact.

АДАПТАЦИОННЫЙ ПОТЕНЦИАЛ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ ПЕРВОКУРСНИКОВ ОБУЧАЮЩИХСЯ В ВУЗЕ

The results of the study of the cardiovascular system adaptation of freshmen students at the university which are presented in the article reflect the peculiarities of adaptation of girls and young men of Russian and Altai nationality to the university in 2017 and 2018. The study of the features of adaptation of the cardiovascular system was carried out taking into account sex, nationality, vegetative status and type of circulation. 160 students were examined. Girls and young men of Altai nationality lived in the regions of the highlands and middle-mountain of the Republic of Altai before entering Gorno-Altai State University, which is located in the low-mountain region. Altai students had to adapt at the beginning of their studies not only to the educational process of the university, but also to the new climatic conditions. The Russians who lived in the conditions of the low-mountain region had to adapt only to the educational process of the university. During the initial period of study at the university a number of factors influence on the body of students, which can lead to tension of adaptation mechanisms and cause health disorders. The results of the study made it possible to establish that taking into account the vegetative status of the subjects the assessment of the adaptation of the cardiovascular system is quite informative and can reveal the tension of the adaptation mechanisms. Most students showed increased activity of sympathetic regulation of vegetative functions – sympathicotonia (60–69 %), balance of influences of sympathetic and parasympathetic systems – eitonia, was observed in 12–40 % students, dominance of parasympathetic regulation – vagotonia was noted in 16.6–20.6 % students. Analysis of adaptation potential taking into account vegetative status and circulatory type revealed that adaptation was satisfactory in the majority of cases, but in Russian young men with vegetative eitonium status and eukinetic circulatory type there was tension in mechanisms of cardiovascular adaptation (2.11 and higher), which indicates increased mobilization of resource opportunities with high probability of their subsequent depletion. According to some researchers, young men are more likely to have a strain on adaptation mechanisms than the girls. The stress of adaptation mechanisms can lead to a decrease in the health level and, as a result, the development of diseases, so in individuals, with an index of functional changes exceeding 2.11 points, should be considered as a risk group. The studies carried out will allow to organize educational work in the university aimed at preserving and improving the health of students, taking into account the peculiarities of their adaptation.

Comparative analysis of functional changes indicators in the body of students with different teaching of physical culture lessons

Based on the position of psychological theory of activity, the question of the need to improve the functional state of students in universities is actualized. On the basis of the ascertaining experiment, the most informative functional test was identified, which characterizes the adaptive mechanisms of the organism. Taking into account the practice of introducing extracurricular activities into physical education of university students, a comparative analysis of the index of functional changes in the organism of students engaged in different ratios of educational process organization forms is carried out.

ХАРАКТЕРИСТИКА МЕТАБОЛІЧНИХ ПРОЦЕСІВ ЕНЕРГОЗАБЕЗПЕЧЕННЯ М’ЯЗОВОЇ РОБОТИ У СПОРТСМЕНІВ 17-21 РОКУ В ЗАЛЕЖНОСТІ ВІД СПОРТИВНОЇ СПЕЦІАЛІЗАЦІЇ

Introduction. The modern way of life and the mode of education affects the health of a primary school pupil. Especially relevant is the study of physical health and adaptive capacity of modern schoolchildren, in terms of the new Ukrainian school . Purpose. to assess the physical development of first-graders who studied in the traditional education system and the new Ukrainian school. Methods. 120 schoolchildren aged 6-7 participated in our research. They were divided into two groups (60 people each): I - pupils of the traditional education system (TES), II – pupils of the new Ukrainian school (NUS). Within the groups, subgroups by gender (30 people each) were distinguished. To identify trends in the physical development of first-graders the conventional method of anthropometry was used, taking into account height (H, cm), body weight (BW, kg), vital capacity (VC, l), muscle strength of the leading arm (dynamometry, kg), blood pressure (ATsyst., ATdiast., mm Hg), heart rate (heart rate, beats / min.). According to the established anthropometric indicators, the indices of physical health were determined: body mass index (BMI, kg / m2), vital index (LI, ml / kg), strength index (SI,%), Rohrer index (IR, kg / m2), level of physical condition (LPC, c. unit) and adaptive capabilities according to the index of functional changes (IFC, c.unit). During the obtained data processing, the methods of variation statistics with the estimation of Student's t-test were used. Results . Boys were characterized by a higher proportion of people with low growth rates, girls - the opposite trend. Among NUS children, a higher proportion of people with excess BW growth rates, regardless of gender, was found. The tendency to increased heart rate was recorded among NUS children, who had a higher proportion of people with VL below normal. The highest percentage of children in terms of dynamometry that meet the age norms was recorded among TES girls. Significant differences between the groups of subjects were found in terms of VL and the strength of the muscles of the hand (with the predominance of TES students). NUS children were characterized by higher BMI. According to the indicators of LI and SI, the advantage of TES children was revealed, for whom the average indicated indicator corresponded to the average level (in the opposite group - low). In general, NUS children were characterized by significantly higher indicators of physical condition. According to the IFC, TES boys were more characterized by an unsatisfactory level of adaptation, while among girls the share with unsatisfactory level of adaptation is higher in terms of NUS training. Originality . An assessment of the physical development of first-graders in terms of traditional and the new Ukrainian school. It was established that the children of the new Ukrainian school were characterized by significantly higher indicators of the functional state level, which indicates the best state of blood circulation in terms of adaptation to learning. In terms of adaptability, boys in the traditional education system were more characterized by an unsatisfactory level of adaptation, while among girls the share with an unsatisfactory level of adaptation is higher in the new Ukrainian school. Conclusions . Children of the new Ukrainian school were characterized by significantly higher indicators of the physical condition level, which indicates an improved state of blood circulation in this group. Among first-graders of the traditional school, the share of people with a high level of physical condition was lower (33.4%), compared with the opposite group (50%). Adaptive abilities among boys corresponded to the stress of adaptation, in girls - unsatisfactory adaptation, regardless of learning conditions. Children of the new Ukrainian school were characterized by an increase in the share of people with satisfactory adaptation (boys - up to 16.7%, girls - up to 26.7%).

Clinical and Functional Dynamics of Physical Working Capacity and Psychological Adaptation in Patients with Acute Coronary Syndrome at the Stages of Rehabilitation

The objective of the research was to analyze the effectiveness of using suggestive therapy in the patients with acute coronary syndrome by assessing the dynamics of the clinical condition and indicators of anxiety.
 Materials and Methods. There were examined 135 patients with non-ST-segment elevation myocardial infarction, 60 patients with the use of the conservative treatment and 75 patients who underwent percutaneous coronary intervention. The dynamics of objective indices, adaptation changes and anxiety indices in the groups of patients with traditional treatment and in the groups of patients with suggestive therapy in addition to the traditional rehabilitation measures, were analyzed.
 Results. Analyzing the dynamics of adaptive indices, it was determined that in the group of patients with non-ST-segment elevation myocardial infarction, who were performed conservative therapy, the dynamics was less significant, which is related to the general desadaptative syndrome. Changes in the group of patients undergoing percutaneous coronary intervention and suggestive therapy, with a decrease of blood pressure, heart rate, and a decrease in the index of functional changes from 3.78±0.15 points before the intervention up to 2.92±0.13 points after suggestive therapy (p<0.01) were more significant. In all groups of patients, high levels of reactive anxiety were observed at the beginning of treatment. As a result of treatment, a decrease in anxiety was noted, but more pronounced changes were seen in the group with the use of suggestive therapy (p<0.05).
 Conclusions. The use of suggestive therapy methods when treating the patients with acute coronary syndrome is an important intervention, that provides a comprehensive approach considering all the components, enhances the patients’ adaptive abilities in the rehabilitation phase, improves the quality and effectiveness of restorative treatment. The use of suggestive therapy at the rehabilitation stage improves the clinical course, reduces anginal manifestations, stabilizes blood pressure and increases exercise tolerance.

Influence of multimodal anesthesia and analgesia on mechanisms of blood circulation adaptation of oncogynecologic patients in the postoperative period

Objective: to assess the influence and eff ectiveness of multimodal anesthesia and analgesia from the standpoint of personalization of compensatory mechanisms of blood circulation adaptation in oncogynecologic patients in the postoperative period. Materials and methods: a study was conducted in patients who underwent surgical interventions on pelvic organs for oncogynecological diseases. The total number of patients was 39 people. Based on anesthesia with sevoflurane at low concentrations and spinal analgesia, all patients underwent multimodal anesthesia. To determine the nature of the functioning of the circulatory system, the adaptive potential was determined by the index of functional changes. For the relief of pain syndrome in patients in the postoperative period, the administration of ketoprofen and nefopam hydrochloride, used according to the doctor’s prescription or in the patient-controlled analgesia mode, as well as the regional blockade of the nerves innervating the anterior abdominal wall (Transversus Abdominis Plane block) was provided. Results: it was revealed that multimodal anesthesia and analgesia, depending on the level of the adaptation potential, differently affects the adaptation and regulatory mechanisms of the systemic circulation of patients, and its vegetative tone, which can cause the risk of complications in the postoperative period. Conclusions: multimodal anesthesia and analgesia, including a combination of central, regional non-narcotic analgesics and blockades, allows to preserve the reserves of systemic circulation and optimize its vegetative component, is effective and safe in oncogynecologic patients with the stress of regulatory mechanisms of adaptation. The use of multimodal anesthesia and analgesia in oncogynecologic patients with unsatisfactory adaptation is a risk factor for the disruption of the regulatory and compensatory mechanisms of hemodynamics and the vegetative tone of the systemic circulation, contributing to the limitation of its work in the first 24 hours of the postoperative period.

FACTOR ANALYSIS OF HEMODYNAMICS DAILY PARAMETERS IN STUDENTS OF THE NORTHERN MEDICAL UNIVERSITY

The purpose was to find out the hidden common factors characterizing the relationship between the parameters of daily hemodynamics in students of the northern medical university. Methods. A factor analysis of hemodynamics data obtained during the daily monitoring of arterial pressure and heart rate in students of Khanty-Mansiysk State Medical Academy (35 boys and 61 girls) was carried out. Results. The analysis revealed two factors in groups. According to the first factor, the mesor factor loading of the index of functional changes (r = 0,833) and the daytime values of the IFI (r = 0,923) and the IAD DB (r = 0,708) achieved significant values in the young men. In the girls: SAD (r = 0,862), DBP (r = 0,767) and IFI (r = 0,919), daily SBP values (r = 0,889), DBP (r = 0,867), IFI (r = 0,942), IV DBP (r = 0,713) (total dispersions are 34,37 % and 39,05 %). The second factor included night hemodynamic parameters in both groups. The young men had : IFI night (r = 0,808), SAD night. (r = 0,813), DBP overnight. (r = 0,892), IV SBP overnight. (r = 0,766), IV DBP at night. (r = 0,778), night decrease of SbP (r = -0,822) and DBP (r = -0,806), in girls: SAD night. (r = 0,776), DBP overnight. (r = 0,836), IV DBP of night. (r = 0,740), SB SBP (r = -0,797) and NS DbP (r = -0,865) (the total variance is 23,04 % and 17,68 %). Conclusion. Differences were found in the structure of the relationship of hemodynamic indices associated with gender. The first factor was formed by daily and average daily hemodynamic indices; in girls its composition is determined by a large number of variables 7 against 3 in boys. The second factor was formed by the night values of hemodynamic indices in both groups. Day and night indices of hemodynamics did not correlate.

Скринінгова оцінка адаптаційного потенціалу при стресі у хірургічних стоматологічних хворих

The degree of stress expressiveness in surgical stomatological patients depends on the adaptation reserve of their organisms. Adaptation to stress in every person is individual. It was found that the most sensitive indicator (marker) of the level of reactivity of an organism in stress is a nociceptive reaction that has the functional stability of neurophysical and neurochemical mechanisms of formation.The aim of the study – to make a screening of the adaptational potential in stomatological patients with different individually-psychological peculiarities under condition of pain stress.Materials and Methods. The objects of clinical observation were 95 surgical stomatological patients. Their individual psychological characteristics were assessed by special questionnaire (S. Novikova, 2006) allowing defi ning the preference of either sthenic or asthenic manifestations in both emotions and behavior of the patients. Neurofunctional research was done by electromyography M-TEST. Stress in patients was induced by electrical stimulation of mental nerve till the appearance of pain reaction that was measured by method of exteroceptive suppression of arbitrary activity of masticatory muscles. It was determined: the threshold of pain, its range and tolerance to pain. According to the results of algometry all the patients were classifi ed into 4 pain perception types. During the operation of the pain factor, a change in the tone of the peripheral vessels was studied by using the index of perfusion (PI), which is according to the literature data recommended for dynamic monitoring of the infl uence of the sympathetic nervous system on hemodynamics. Adaptational vegetative cardiovascular reactions to stress were assessed by the Baievskyi index of functional changes (IFC)=0.011 pulse rate + 0.014 systolic blood pressure + 0.008 diastolic blood pressure +0.014 age + 0.009 body weight – 0.009 growth – 0.27.Results and Discussion. 26 patients with asthenic psychotype in which the threshold of pain and pain tolerance were not high belong to the pain perception type 1. In these patients adaptation of the autonomic nervous system to stress were unsatisfactory (functional changes index (IFC)=(3.35±0.49) points). In patients with the pain perception type 2 threshold of pain sensitivity was similar to those of the type 1, but the range proved to be much longer because of the high threshold of pain tolerance. In this group we noticed functional manifestations of stress-induced analgesia accompanied by exertion of adaptation mechanisms – IFC=(2.86±0.14) points. Such pain perception type was diagnosed in 35 patients with a great prevalence of sthenic features. High pain thresholds were diagnosed in patients with pain perception type 3 and 4, however, owing to the insuffi cient activity of endogenous antinociceptive system in the group 3 the range of pain sensitivity was short. Such pain perception type was found in 15 patients. They manifested both sthenic and asthenic features during psychological testing, Baievskyi stress index (IFC – (3.48±1.12) points) showed unsatisfactory adaptation of cardiovascularsystem to stress in these patients. High indicators of antinociceptive system activity were found in patients with pain perception type 4 including personalities having considerable sthenic characteristics. They showed to have tolerable adaptation of cardiovascular system to stress (IFC – (2.35±0.89) points).Conclusions. The results of clinical observations suggest that the adaptive capacity of patients with stressful (pain) effects depends on their individual psychological characteristics, the level of activation of antistress (antinociceptive) mechanisms, the state of the autonomic nervous system, which are components of the general non-specifi c reactivity of the organism. Patients with increased pain sensitivity are characterized by low resistance to stress, lability of the autonomic nervous system, low level of adaptive capacity. High resistance to stress is characteristic for subjects with stenotic psycho-emotional type, which have high thresholds for pain sensitivity. Adaptation capabilities of the body of patients with stress should be taken into account when they are medically prepared for surgical intervention.

Age-related dynamics of functional parameters in men in the polar region

We compared the functional parameters in men at the age of 20–69 years in a single-step cross-sectional study in order to find evidence of increased functional parameters in residents of the Polar region. In men of this age range residing in the Polar region, a tendency toward a steady decline in a number of parameters was found: height, strength, muscle working capacity, balancing of the body when standing on one leg, vital capacity of the lungs, resistance to hypoxemia, cardiac output, level of physical strength, adrenocorticotropic hormone and testosterone levels, an increase in the body mass index, index of coordination (motor coordination impairment), visual motor response time, systolic and diastolic blood pressure, index of functional changes, and insulin. Such a functional decline was more prominent in men at the age of 50 years and older.