In this article, we use the optimal homotopy asymptotic method (OHAM) to compute the solution of two‐dimensional incompressible laminar boundary layer flow over a flat plate (Blasius problem). The obtained results for the stream function and velocity profile were comparable in terms of accuracy with that obtained by Esmaeilpour and Ganji (2007) who studied the same problem using the homotopy perturbation method and results obtained by using a numerical method (RK4). The good agreement obtained shows the effectiveness of OHAM. © 2013 Wiley Periodicals, Inc. Heat Trans Asian Res, 43(3): 197–203, 2014; Published online 19 June 2013 in Wiley Online Library (wileyonlinelibrary.com/journal/htj). DOI 10.1002/htj.21070
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