Rail corrugation appears as a periodic irregularity on the rail running surface that causes severe dynamic loads at the wheel-rail interface. These dynamic forces may generate ground-borne vibrations that propagate from the line to the surrounding buildings causing discomfort to residents. Rail grinding is the most used countermeasure for the mitigation of corrugation. However, this maintenance operation determines high operative costs if frequently performed and must be carefully scheduled. To this end, it is important to assess the effectiveness of other mitigation solutions that may prevent or slow down its growth. The main objective of this study is to investigate the formation of rail corrugation on a sharp curve of the Cityringen underground line in Copenhagen. A wheel-rail interaction model is developed in the frequency domain to identify the root causes of the problem on the specific curve and predict the corrugation wavelength. Once the accuracy of the model is tested against experimental observations on the reference curve, it is used to explore the effectiveness of different mitigation actions, such as the use of friction modifiers, the variation of the speed, track design and track gauge. The results indicate that friction modifiers and speed variation are the most effective measures.