Cyber-Physical Systems (CPS) are increasingly used in many complex applications, such as autonomous delivery drones, the automotive CPS design, power grid control systems, and medical robotics. However, existing programming languages lack certain design patterns for CPS designs, including temporal semantics and concurrency models. Future research directions may involve programming language extensions to support CPS designs. On the other hand, JSF++, MISRA, and MISRA C++ are providing specifications intended to increase the reliability of safety-critical systems. This article also describes the development of rule checkers based on the MISRA C++ specification using the Clang open-source tool, which allows for the annotation of code and the easy extension of the MISRA C++ specification to other programming languages and systems. This is potentially useful for future CPS language research extensions to work with reliability software specifications using the Clang tool. Experiments were performed using key C++ benchmarks to validate our method in comparison with the well-known Coverity commercial tool. We illustrate key rules related to class, inheritance, template, overloading, and exception handling. Open-source benchmarks that violate the rules detected by our checkers are also illustrated. A random graph generator is further used to generate diamond case with multiple inheritance testdata for our software validations. The experimental results demonstrate that our method can provide information that is more detailed than that obtained using Coverity for nine open-source C++ benchmarks. Since the Clang tool is widely used, it will further allow developers to annotate their own extensions.