Plasma spraying techniques are commonly employed for the deposition of thermal barrier coatings (TBCs) due to their efficiency and cost-effectiveness. However, ensuring uniform coating thickness and quality on complex free-form surfaces poses significant challenges. This paper investigates the influence of spraying trajectory and related parameters (spraying distance, angle, velocity) on coating thickness distribution, addressing the need for simplified analysis among numerous variables affecting coating quality. Different from the predominantly existing research focusing on flat or rotationally symmetric substrates, this study delves into the planning of spray trajectories for free-form surfaces, which is crucial for industries dealing with complex components, such as turbine blades. Innovative optimization approaches are employed to refine spray trajectories and improve coating consistency. Through theoretical modeling, simulation and experimental validation, the impact of spray parameters on coating thickness was demonstrated. Both the mean and disperssion coefficient errors of the coating thickness, obtained by the theoretical prediction model and the spray experiments, are lower than 10 %. The normal spray trajectory makes the coatings more evenly distributed, and the coating uniformity is at least 50 % higher than that of the codirectional spraying. This research contributes to the optimization of plasma spraying processes, particularly on irregular surfaces, thereby facilitating the development of high-performance TBCs for industrial applications.