Federal Center Research Articles

Political Situation and Ideological Background in Bavaria on the Eve of the Beer Hall Putsch of 1923

The purpose of the article is to determinate the ideological platforms of various political forces in Bavaria in 1923 before the Hitler putsch. The study considers movements of an all-German nature, rooted in the situation of 1918/1919, and local South German initiatives related to the peculiarities of the geographical location of the region and contradictions with the federal center. The novelty of this study lies in a clear categorization of various political groups with the creation of conditions for a thorough study of the process of participation of military circles in the vicissitudes of the state crisis of 1923. The complex of existing contradictions manifested itself most clearly in Bavaria, which became a refuge for a large number of paramilitary organizations, the legitimacy of which was in question. Tensions were also observed in relations between the regional and all-German Reichswehr, which were formally a single structure. The involvement of archival materials allows us to make a conclusion about the strong regional isolation of Bavaria and the orientation of local political groups towards neighboring countries.

АКТУАЛЬНЫЕ ПРОБЛЕМЫ РЕГУЛИРОВАНИЯ ПРОФЕССИОНАЛЬНОЙ МОБИЛЬНОСТИ КАДРОВ

The article discusses the current problems of professional mobility of personnel in the context of the introduction of sanctions against Russia by the United States and the European Union and the new subjects formed in accordance with the Constitution of the Russian Federation and their admission to the Russian Federation. It is noted that in 2014-2023, migration processes occur in the subjects of the Russian Federation, which are characterized by high dynamics and affect the number, types and directions of migration, the socio-demographic profile of the moving population, including professional personnel to new subjects of the Russian Federation. As a result, new representative, legislative and executive-administrative authorities are being created in these subjects. This directly affects the creation of organizational structures, the selection, placement and retraining of personnel and their relocation, as a rule, to new positions from the federal center and from other subjects of the Russian Federation in the order of rotation and promotion of specialists to new regions. That is, in fact, there is a professional mobility of specialists.

СОЦИАЛЬНЫЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ НАУКОГРАДА БИЙСК

The article discusses the social problems of the Biysk science city. Gaps have been identified in a number of areas of development: education, healthcare, culture, as well as the infrastructure of the city. The all-Russian problems associated with the decline of the population, the outflow of young people to other cities, insufficient funds to maintain the social sphere, and the deterioration of urban infrastructure are emphasized. The study revealed that by a number of indicators Biysk is below the regional and district values, despite the high status of the city of science and the existing scientific and production potential. A comparative analysis of the socio-economic development strategy of the science city and the plan for its implementation revealed a number of issues that either were not included in the plan and strategy for the development of the science city, or to which formal attention was paid. It is suggested that the degradation of the city is associated with a decrease in annual subsidies from the federal center, with the inability to socially build a successful model of a science city, with the existing inconsistency of management processes and their practical effect only in relation to economically successful regions.

Reputation core of Russian authorities: the case of the regional level of executive power

The importance of studying the reputation of authorities is connected, on the one hand, with the formation of a consolidated system of political power and, on the other hand, with the highly social orientation of the category of the ‘reputation of authorities’, reflecting the value-based attitude of citizens towards them. The article presents the results of research aimed at the analysis of the reputation of Russian authorities, with a special focus on the regional branch of executive power. The paper examines the reputation of Russian authorities of different levels and branches using the example of regional executive bodies. The author determines the structure and features of the reputation core of the conceptual category ‘Russia’s authorities’ understood both as federal and municipal authorities of the Russian Federation as a whole. The article also offers a comparison of the reputation core of regional executive authorities with that of ‘Russia’s authorities’ in general. The methods used in this research are expert assessment and population surveys conducted in six regions of Central Russia. The study has revealed the main characteristics constituting the reputation core of executive authorities and described their specificity in different regions. Based on the results of the theoretical and empirical analyses, the author proposes a novel approach to defining the structure of the reputation core characteristic of the federal and regional executive authorities. The reputation core is a multi-component conceptual construct dominated by several integrating characteristics such as honesty, responsibility, justice, concern for and protection of citizens. No differences in the structure of the reputation core of the federal and regional executive authorities have been identified. However, the degree to which these characteristics manifest themselves varies. The reputation of regional authorities is assessed based on a system of values, expectations and the results of their work with the federal centre, citizens’ experience of communication with regional authorities and the assessment of their activity. The reputation of the regional executive authorities is characterised by lesser stability of the conceptual characteristics of the near periphery and greater dynamism of the outer conceptual boundaries, especially in specific regions.

ГОСУДАРСТВЕННОЕ УСТРОЙСТВО СОВРЕМЕННОЙ РОССИИ В КОНТЕКСТЕ ИСТОРИИ ЕЕ ГОСУДАРСТВЕННОСТИ

The article considers in a historical context one of the components of modern Russian statehood – the state structure in the form of connection between the center and the territories (at the end of the 20th – the first quarter of the 21st century). Pre-revolutionary Russia was a unitary state, which did not exclude the presence of national administrative units, for example, the Kingdom of Poland, the Grand Duchy of Finland, the presence of elements of political autonomy in some of them, and features in the organization of government bodies. As is known, numerous Soviet constitutions proclaimed the RSFSR, and then the USSR, as federal states, which in fact they were not. All the features inherent in federal states were neutralized by the actions of the highest authorities in the person of the leadership of the ruling party. The state structure of modern Russia, being federal, in some cases differs from the principles generally accepted in world practice. Asymmetry, preservation of the national principle and the use of the matryoshka type in the construction of several federal subjects, etc. are both part of Russian traditions and a tribute to the past, which cannot be ignored. The increased centralization in the relationship between the federal center and the constituent entities of the federation can be explained by the need to concentrate all the forces and means of the state in the context of a special military operation.

Роль волонтерского движения в сфере гражданско-патриотического воспитания: опыт Нижегородской области

The article analyzes the program-target approach in the field of civic and patriotic education and the practice of its implementation at the regional level. The purpose of this work is to determine the specifics of the role of the volunteer movement (volunteerism) in this area on the example of the Nizhny Novgorod region. The author of the article highlighted the main parameters of the work of public authorities at various levels to promote the spread of volunteerism in general in Russia and in the region. Special attention is paid to the activities of Nizhny Novgorod volunteers who contribute to patriotic education and the formation of civic political culture in the region in the context of the implementation of the institute of volunteerism. The research interest is also rooted in the plane of youth policy. The main results, illustrating the features of the experience of the named region, are summarized. Firstly, it is concluded that the institute of volunteerism in the Nizhny Novgorod region is being strengthened every year, its goals and objectives are being updated under the influence of the policy pursued by the federal and regional authorities. Secondly, civil-patriotic actions and events are the foundation of volunteer activity in the Nizhny Novgorod region. Thirdly, the federal center is actively involved in the training of volunteers in the region and the consolidation of the volunteer movement here. Fourth, the prospects for the development of volunteerism in the Russian Federation and the Nizhny Novgorod region, problems and risks within the framework of the civil-patriotic block of the volunteer movement are identified. Fifthly, it can be stated that the expansion of the tools of public associations leads to the fact that the sphere of activity of Nizhny Novgorod volunteers is filled with another direction – cultural education, which is one of the vectors of preserving historical memory and an important factor in preserving patriotic values.

Уровень благосостояния населения в регионах Российской Федерации: институциональное и инфраструктурное обеспечение

The article examines the level of population well-being in the regions of the Russian Federation from the standpoint of their institutional and infrastructural support. It is a high-quality institutional environment and developed infrastructure that are the most important conditions for ensuring the population well-being in Russian regions. The authors note a significant differentiation in income levels and their polarization (by fund ratio, decile ratio), which is reflected in the poverty level of the population of the regions. The article presents the results of a study on two regions of the Russian Federation: one leading region and one outsider region, identified by the results of an earlier study conducted by the authors. Yamalo-Nenets Autonomous District is represented as the leader in terms of well-being, while the Republic of Ingushetia is an outsider. The authors proved that the Yamalo-Nenets Autonomous District, being in an unfavorable climatic zone, forms institutional and infrastructural conditions conducive to systematic work on social development and support of the population. At the same time, there is an increase in indicators of social inequality in the region, which may contribute to the development of social tension. Regarding the outsider, the Republic of Ingushetia, it was shown that, having conditions favorable for life and work, and forming an adequate institutional environment and social infrastructure, the region is characterized by an unfavorable social situation: low incomes of the population, high unemployment. The authors believe that it is possible to solve problems in the social sphere with the effective realization of the potential of the region and significant support from the federal center.

S-15-2: COMMUNITY-BASED APPROACHES TO PREVENTION AND MANAGEMENT OF HYPERTENSION

There are multiple level factors that contribute to hypertension prevalence and control across various racial/ethnic populations. Hypertension rates in non-Hispanic Black (African American) adults in the USA are among the highest globally, impacted by the social determinants of health. Clinical approaches include team-based care, encouraging self-measured blood pressure, and strengthening community-clinical linkages. Prevention of new-onset hypertension and complications has been clearly demonstrated with community-level NaCl substitution in China and Peru. In the USA, Black population treatment approaches as community interventions include early initiatives from the Association of Black Cardiologists and the Healthy Heart Community Prevention Project (HHCPP) in New Orleans. The HHCPP was one of the early adopters of using barbers and hair stylists as hypertension control centers, working with faith-based institutions, and doing community education and outreach. Evidence-based approaches, now proven to be effective, include the faith-based treatment program for hypertension in New York, NY and a very successful in cluster-randomized trial demonstrating hypertension control in Black barbershops in Los Angeles, CA. The positive components of the Los Angeles barbershop intervention include trusted site of blood pressure intervention, physician-pharmacist collaboration, and effective anti-hypertensive medication including initial two drug protocol with amlodipine and a long-acting RAS blocker, and the appropriate use of aldosterone antagonists. Ongoing research include a small pilot study, simple text messaging and social support in New Orleans for medication adherence which will be reported at the AHA 2022 scientific sessions, and a large church-based health intervention study addressing primary prevention, including hypertension in New Orleans among 42 selected African American churches using community health workers in a combination of exercise weight-loss programs, self-monitoring blood pressure, glucose, and physical activity, and group education centers. In the USA, the American Heart Association in conjunction with the US Department of Health and Human services have initiated a national hypertension control initiative. Overarching strategies include patient and public education, community outreach and integration, and healthcare organization including provider and clinician training, as well as management evaluation of the project. This national program will engage community partners with federal health centers. In conclusion, hypertension can be controlled with evidence-based medicines, not only in clinical settings, but also with interventions in the community environment. Therapeutic lifestyle and evidence-based pharmacotherapy along with self-monitored blood pressure can lead to blood pressure control, especially in racial/ethnic populations.

Surgical management of spinal schwannomas arising from the first and second cervical roots: Results of a cumulative case series.

Schwannomas of the first and second nerve roots are rare neurosurgical entities, harboring specific surgical features that make surgical resection particularly challenging and deserve specifics dissertations. This study is a retrospectively analysis of 14 patients operated in two different neurosurgical centers: the San Filippo Neri Hospital of Rome and the Federal Centre of Neurosurgery of Tjumen. In the last 6 years, 14 patients underwent neurosurgical resection of high cervical (C1-C2) schwannomas, in two different neurosurgical centers. Patients data regarding clinical presentation, radiological findings, and surgical results were retrospectively analyzed. The mean age was 50 years (range 13-74), the follow-up mean duration was 30 ± 8.5 (range 24-72 months), and there was no significant differences among different tumor locations (intradural, extradural, and dumbbell). Surgical results were excellent: gross total resection was achieved in all cases and there were no intraoperative complications or postoperative mortality. All patients presented postoperative clinical improvement except one who remained stable. Karnofsky performance status, at the last follow-up, confirmed a global clinical improvement. No vertebral artery (VA) injury neither spinal instability occurred; nerve root sacrifice was reported in one case. Neurosurgical treatment of C1-C2 schwannomas is associated with good outcomes in terms of extent of resection and neurological function. In particular, dumbbell shape and VA involvement do not represent limitations to achieve complete tumor resection and good clinical outcome. In conclusion, microsurgery represents the treatment of choice for C1-C2 schwannomas.

ОЦЕНКА УРОВНЯ ЦИФРОВИЗАЦИИ В РЕГИОНАХ РОССИИ

The article attempts to analyze the current practice and methods for assessing the levels of the digital economy in the regions of Russia, reveals its theoretical essence and practical significance.The main goal of the article is to study the assessment of the level of digitalization in the regions of Russia – for this, a critical analysis of existing assessment methods and approaches was carried out, identifying their strengths and weaknesses. Based on the results of this study, the author came to the conclusion that it is necessary to develop a new theoretical and methodological framework for assessing the level of digitalization of the economy based on data assessing the demand and supply of digital services in real time. This will make it possible to timely identify gaps in the levels of digitalization of Russian regions and promptly solve these problems by introducing best practices, public-private partnership mechanisms, tax incentives for enterprises carrying out digital transformation, and infrastructure budget funding from the federal center to the regions. Further research will identify some areas where digital technology is advancing and lagging behind in others, and explore these issues in more detail.

Особенности течения системного ювенильного идиопатического артрита среди пациентов, получающих генно-инженерную биологическую терапию: результаты анализа Федерального регистра Российской Федерации

Background. A register is a critical component of the healthcare system. It consists of the informational part (number of patients, spectrum and severity of pathology, dynamics of each patient's condition, administration of specific drugs, and therapeutic effects) and an analytical part (treatment efficacy, planning individual and regional needs for specific drugs and therapeutic effects, development and evaluation of management protocols, etc.). In Russia, despite the existence of the National Federal Register, the number of parameters collected is limited; the Register lacks information about the disease course, clinical characteristics of patients, outcomes, and treatment costs. Thus, the existing shortcomings of the Federal Registry do not allow us to address the problems related to the management of the healthcare quality for patients with systemic juvenile idiopathic arthritis (sJIA). Objective. To analyze geographical, demographic, and clinical characteristics of sJIA patients receiving biologicals, time to diagnosis, and time to admission to a Federal Center according to the Federal Register of the Russian Federation. Patients and methods. We conducted a retrospective study that included 927 sJIA patients receiving biologicals according to the Federal Register. Results. The majority of patients resided in the Central and Volga Federal Districts (221 (23.8%) and 206 (22.3%), respectively). Half of the patients (n = 472 (50.8%)) had their disease onset before the age of 5 years. The following symptoms were registered at disease onset: fever (n = 908 (98%)), rash (n = 748 (80.7%)), enlarged liver and/or spleen (n = 562 (60.6%)), and serositis (n = 198 (21.4%)). A total of 708 children (76.4%) had active arthritis at the moment of disease onset, whereas 130 patients developed arthritis later. Median time to the development of articular syndrome was 24 months. Median time between the disease onset and the diagnosis was 2.93 months. Median time between the first symptoms and admission to a Federal Center was 6.7 months. Conclusion. Analysis of data from the Federal Register of sJIA patients receiving biologicals demonstrated that sJIA in the Russian population is characterized by an acute and early onset with severe extra-articular manifestations, and articular syndrome. The diagnosis was usually verified and the patients were hospitalized to specialized rheumatology departments of Federal Centers within 5 months. Key words: Federal Register, systemic juvenile idiopathic arthritis, biological, disease course

СЕРОЛОГИЧЕСКИЙ МОНИТОРИНГ НА НАЛИЧИЕ ВИРУСНЕЙТРАЛИЗУЮЩИХ АНТИТЕЛ У ВАКЦИНИРОВАННЫХ ПРОТИВ БЕШЕНСТВА ДОМАШНИХ ПЛОТОЯДНЫХ

The article shows the results of serological monitoring of dogs vaccinated against rabies inhabiting urban and rural areas of the Republic of Kazakhstan. During the field trips to Petropavlovsk, Almaty, Shymkent, and rural districts of the North Kazakhstan region (Yesil, Kyzylzhar) and Zhambyl region (Baizak, Zhambyl), according to the scientific project schedule, a group of researchers collected serum blood samples from dogs vaccinated against rabies using the vaccines produced by various manufacturers, regardless of dog gender, aged from 1 to 15 years. The mentioned locations of blood samples collection were determined based on the study of the epidemiological characteristics of the country's territory over the past ten years in terms of animal rabies. The blood serum was analyzed using the available method, i.e. the “ELISA test system for determining the level of antibodies to the serum rabies virus in animals vaccinated against rabies using the indirect ELISA method” (manufacturer FSBSI «Federal Center for toxicological, radiation, and biological safety», Russia). The results of post-vaccination serological studies of blood serum collected 1.5-5 months after vaccination from dogs of different age groups and gender, inhabiting the northern and southern regions of the country, immunized with inactivated rabies vaccines, indicate the establishment of the adequate protective barrier for the susceptible population of domesticated carnivores.

The place of the Republic of Karelia in the Arctic zone of the Russian Federation

The article analyzes the current state and prospects of development of the Republic of Karelia, which is one of the Arctic regions of the Russian Federation. The changes in various spheres of life of the republic, as well as practical steps of the leadership of the region and the federal center aimed at improving the quality of life of the local population are considered. Special attention is paid to the factors that have both a positive and negative impact on improving the well-being of the region.

Влияние витаминизированного препарата «Нитамин» на аминокислотный и химический состав мяса кроликов

The article presents the results of studies which purpose is to study the effect of the drug «Nitamin » on the amino acid and chemical composition of rabbit meat. Studies to determine the amino acid and chemical composition of rabbit meat were carried out at the Federal State Budgetary Institution «Federal Center for Animal Health» (FGBI «ARRIAH»), the processing of the results obtained during the study was carried out at the Department of Parasitology and Veterinary and Sanitary Expertise of the Federal State Budgetary Educational Institution of Higher Education MGAVMiB– MVA named after K. I. Scriabin. The objects of the study were the carcasses of rabbits of the experimental and control groups. The rabbits of the experimental group were grown using the drug «Nitamin» (the animals received «Nitamin» with water for drinking, from 60 days of age for four days and from 74 days of age for four days at the rate of 1 ml / 1 liter of water), the control group did not receive the drug. The results of the studies showed that the meat of rabbits treated with «Nitamin» with dri nking water, in terms of the total number of essential and non-essential amino acids, prevailed by 2,3 and 0,7 %, respectively, in comparison with the meat of rabbits of the control group. The mass fraction of protein in the meat of experimental rabbits significantly increased by 2,5 %, while the mass fraction of fat decreased by 1,8 % compared with the samples of the control group. The amount of iron in the meat of rabbits of the experimental group significantly increased by 83,33 % compared to the control group. The obtained data on the use of the drug «Nitamin » in rabbit breeding indicate an increase in the nutritional value of the resulting product while maintaining the dietary properties of rabbit meat.

Some data on prevalence of microscopic fungi in conditions of the Republic of Tatarstan

Research on plant feedstock for farm animals and poultry is now a pressing issue. Seeding with field isolates occurs in the soil layer in the autumn period. The infestation of isolates remains in the form of spores on crop residues during the winter period. The research aimed to conduct a mycological assessment of the field isolates prevalence in soil, green mass, and agricultural products in the farms of the Agricultural Production Cooperative [APC] “Tukaya” of the Baltasinsky district, the Agricultural firm “Archa” of the Arsky district, and the APC “Kubnya” of the Kaibitsky district of the Republic of Tatarstan. The mycological screening was carried out in the specialized laboratories of the Federal Center for Toxicological, Radiation and Biological Safety. To determine the toxicity, a biotesting method based on the survival rate of ciliated cultures was used after one hour of exposure in the extract of the studied product. The climatic conditions of the spring-summer period of 2020 were characterized by increased humidity in combination with temperature changes. In the research, a spread of fungi of the genus Fusarium (F. oxysporum, F. graminearum F. sporitrichioides), Penicillium (P.notatum, P.glaucum, P.chusodepim, P. expansium) was detected in crops. And fungi of the genus Aspergillus were more often sown in grain feeds (A.fumigatus, A. flavus, A. niger). During the determination of toxicity, it was found that all the objects studied: soil, green mass, and feed are non-toxic, the survival rate of infusoria was 86%–100%. The authors recommend conducting regular feed screening and taking preventive measures that will make it possible to prevent the spread of aggressive field isolates in the agricultural complexes of the Republic of Tatarstan.

Evaluation of the Influence of the Federal Center for Cardiovascular Surgery on Cardiovascular Disease Detection Rates in Penza Region

Evaluation of the Influence of the Federal Center for Cardiovascular Surgery on Cardiovascular Disease Detection Rates in Penza Region

АНАЛИЗ ПРЕДОСТАВЛЕНИЯ МЕЖБЮДЖЕТНЫХ ТРАНСФЕРТОВ СУБЪЕКТАМ РОССИЙСКОЙ ФЕДЕРАЦИИ ЗА СЧЕТ СРЕДСТВ ФЕДЕРАЛЬНОГО БЮДЖЕТА

The article analyzes the provision of transfers (grants, subsidies, subventions and other types of financial assistance) from the federal budget to the subjects of the Russian Federation. On the basis of the analysis carried out, conclusions were drawn confirming the vector of centralization of financial resources at the level of the federal center, with the aim of their subsequent direction to equalize the budgetary provision of the regions of Russia. The authors made a generalization about the inefficiency of the existing model of interbudgetary regulation, built on a rigid management hierarchy, which hinders the growth of incentives for the regions’ interest in building their own economic potential.

Влияние комбинированного противопаразитарного лекарственного препарата на жирно-кислотный состав и безопасность мяса перепелов

The article presents the results of studies on the effect of the combined antiparasitic drug «Praziver », used to prevent heterakidosis, on the fatty acid composition and microbiological safety of quail meat of the Manchurian quail breed. The studies were carried out at the Department of Parasitology and Veterinary and Sanitary Expertise of the Federal State Budgetary Educational Institution of Higher Education MSAVM&B-MVA named after K.I. Skryabin, the fatty acid composition and microbiological safety of quail meat were determined at the Federal State Budgetary Institution «Federal Center for Animal Health». The quails were divided into two groups of 10 animals each, the first group received the drug «Praziver» with water for drinking from 14 days of age for 7 days at a dose of 0,5 ml / 1 liter of water, the second group was the control. The fatty acid composition of quail meat was determined according to GOST R 55483-2013 «Meat and meat products. Determination of fatty acid composition by gas chromatography». According to the results obtained, the use of the drug «Praziver» does not have a negative effect on the content of fatty acids in quail meat, therefore, does not reduce the biological value of the resulting meat. When studying the safety indicators of quail meat treated with Prasiver, no pathogenic and conditionally pathogenic microflora were found, the meat meets the requirements of TR TS 021/2011 «On Food Safety».

Анализ эффективности локального протокола диагностики перипротезной инфекции

The diagnosis of periprosthetic joint infection is a difficult task because there is no absolute test to confirm or rule out infection. We have developed a local protocol for diagnosing periprosthetic joint infection to use a combination of diagnostic studies with the highest level of sensitivity and specificity.The purpose of the study: To evaluate the effectiveness of a local protocol for diagnosing periprosthetic joint infection to determine surgical treatment tactics.Methods. We analyzed 283 audits that took place during 2020-2022 at the Federal Center for Traumatology, Orthopedics and Endoprosthetics (Smolensk, Russian Federation). Patients with a preliminary diagnosis of aseptic loosening of knee or hip joint endoprosthesis components and periprosthetic joint infection were monitored. All patients were examined in accordance with the local protocol for the diagnosis of periprosthetic joint infection, which includes clinical and radiological data, CRP and ESR, analysis of the cellular composition of synovial fluid, microbiological examination of biopsies, endoprosthesis components, planned and frozen sections. The final diagnosis was made taking into account clinical and laboratory data. The effectiveness was assessed by delayed treatment results. Results. Positive microbiological cultures were isolated in 165 patients (58%), 150 patients had increased cytosis of synovial fluid (53%), leukocyte esterase was increased in 147 cases, according to the results of an urgent histological examination, 159 conclusions of «infectious type membrane» (56%) were obtained, a combination of increased ESR and CRP was observed in 93 cases.Conclusions. Analysis of the local periprosthetic joint infection diagnostic protocol showed that each stage of diagnosis allows to identify additional cases of infection, therefore, all patients admitted for revision endoprosthetics should be examined throughout hospitalization. The inclusion of urgent histological diagnostics at the intraoperative stage makes it possible to change the tactics of surgical treatment in a timely manner. In general, the local protocol of step-by-step diagnosis of periprosthetic joint infection with the inclusion of urgent histological examination helps to increase the chances of a successful outcome of revision endoprosthesis surgery, regardless of the nature of loosening.

ОБЕСПЕЧЕНИЕ ЭКОНОМИЧЕСКОЙ БЕЗОПАСНОСТИ НА УРОВНЕ СУБЪЕКТА РОССИЙСКОЙ ФЕДЕРАЦИИ

The author presented the results of the analysis of the provision of the subjects of the Russian Federation with organizational and regulatory instruments to ensure economic security in modern financial and economic conditions. The arguments in defense of strengthening measures to ensure economic security in the Russian regions are presented and approaches to strengthening the organizational and economic mechanism for ensuring regional economic security are substantiated. The role of the federal center in the implementation of the policy of strengthening economic security at the level of the subject of the Russian Federation is outlined. The ways of consistently strengthening the economic security of Russian regions by increasing the degree of awareness in making strategic and tactical decisions by the state authorities of the subjects of the Russian Federation responsible for socio-economic development are proposed. Activities to ensure the economic security of the region should be mandatory, regularly reflected in the strategy of socio-economic development of the subject of the Federation, as well as in tactical documents aimed at socio-economic development, including state programs of the region, as well as special tactical documents on planning measures to strengthen economic security, developed for each year.