Providing blood with high quality at the lowest cost and the shortest time is main challenge of blood supply chain management. This paper presents a new model for designing a dynamic and three level blood supply chain incorporating the quality issues. The proposed model intends to locate facilities, and to determine the best strategy for blood allocation by minimizing both cost and time and maximizing the customer satisfaction based on quality of blood delivery. In order to deal with consideration of real world, intricacies such as blood freshness, both separation and apheresis extraction methods, Cross match to Transfusion ratio (C/T) and equipment failure have been involved. Also, Interval Evidential Reasoning (IER) approach is applied to handle the uncertainty of blood product demand. Since the proposed model is NP-hard, MOPSO and NSGAII algorithms are utilized to solve it. Finally, to demonstrate the applicability of the problem some numerical examples are designed in different sizes and the most favorable algorithm is determined using TOPSIS method.