Epilepsy Detection Research Articles

MRP-Net: Seizure detection method based on modified recurrence plot and additive attention convolution neural network

Electroencephalographic (EEG) signals play an important role in the detection of seizures in epilepsy, and accurate detection of seizures can buy patients valuable treatment time. However, most seizure detection methods ignore the nonlinear, implicit characteristics of EEG, which has some impact on the accuracy of detection. Therefore, in this paper, we propose an EEG epilepsy detection network (MRP-Net) based on modified recurrence plot (MRP) and additive attention convolution neural network. This network can fully take into account the nonlinear, occult characteristics of EEG which can be mapped to the two-dimensional plane and served as the input of additive attention convolution neural network to automatically learn, analyze, and extract the EEG characteristics of seizures. The performance of the proposed method was evaluated on the Bonn University dataset and the SWEC-ETHZ short-term dataset. Sensitivity, specificity and accuracy were 100% in multiple detection tasks in the University of Bonn single-channel EEG dataset. The sensitivity, specificity and accuracy of SWEC’s short-term, multi-channel EEG dataset were 99.77%, 99.57% and 99.69%, respectively, higher than the latest methods (3.76%, 4.73% and 4.27%). The results of the experiments show that the network in this paper is superior and universal in epilepsy detection.

Performance comparison of bio-inspired and learning-based clustering analysis with machine learning techniques for classification of EEG signals.

A comprehensive analysis of an automated system for epileptic seizure detection is explained in this work. When a seizure occurs, it is quite difficult to differentiate the non-stationary patterns from the discharges occurring in a rhythmic manner. The proposed approach deals with it efficiently by clustering it initially for the sake of feature extraction by using six different techniques categorized under two different methods, e.g., bio-inspired clustering and learning-based clustering. Learning-based clustering includes K-means clusters and Fuzzy C-means (FCM) clusters, while bio-inspired clusters include Cuckoo search clusters, Dragonfly clusters, Firefly clusters, and Modified Firefly clusters. Clustered values were then classified with 10 suitable classifiers, and after the performance comparison analysis of the EEG time series, the results proved that this methodology flow achieved a good performance index and a high classification accuracy. A comparatively higher classification accuracy of 99.48% was achieved when Cuckoo search clusters were utilized with linear support vector machines (SVM) for epilepsy detection. A high classification accuracy of 98.96% was obtained when K-means clusters were classified with a naive Bayesian classifier (NBC) and Linear SVM, and similar results were obtained when FCM clusters were classified with Decision Trees yielding the same values. The comparatively lowest classification accuracy, at 75.5%, was obtained when Dragonfly clusters were classified with the K-nearest neighbor (KNN) classifier, and the second lowest classification accuracy of 75.75% was obtained when Firefly clusters were classified with NBC.

Detection of EEG signals in normal and epileptic seizures with multiscale multifractal analysis approach via weighted horizontal visibility graph

Electroencephalogram (EEG) signals contain important information about the regulation of brain system. Thus, automatic detection of epilepsy by analyzing the characteristics obtained from EEG signals has important research implications in the field of clinical medicine. In this paper, the horizontal visibility graph (HVG) algorithm is used to map multifractal EEG signals into complex networks. Then, we study the structure of the networks and explore the nonlinear dynamics properties of the EEG signals inherited from these networks. In order to better describe complex brain behaviors, we use the angle between two connected nodes as the edge weight of the network and construct the weighted horizontal visibility graph (WHVG). In our studies, fractality and multifractality of WHVG are innovatively used to analyze the structure of related networks. However, these methods only analyze the reconstructed dynamical system in general characterizations, they are not sufficient to describe the complex behavior and cannot provide a comprehensive picture of the system. To this effect, we propose an improved multiscale multifractal analysis (MMA) for network, which extends the description of the network dynamics features by focusing on the relationship between the multifractality and the measured scale-free intervals. Furthermore, neural networks are applied to train the above-mentioned parameters for the classification and identification of three kinds of EEG signals, i.e., health, interictal phase, and ictal phase. By evaluating our experimental results, the classification accuracy is 99.0%, reflecting the effectiveness of the WHVG algorithm in extracting the potential dynamic characteristics of EEG signals.

Effective Early Detection of Epileptic Seizures through EEG Signals Using Classification Algorithms Based on t-Distributed Stochastic Neighbor Embedding and K-Means.

Epilepsy is a neurological disorder in the activity of brain cells that leads to seizures. An electroencephalogram (EEG) can detect seizures as it contains physiological information of the neural activity of the brain. However, visual examination of EEG by experts is time consuming, and their diagnoses may even contradict each other. Thus, an automated computer-aided diagnosis for EEG diagnostics is necessary. Therefore, this paper proposes an effective approach for the early detection of epilepsy. The proposed approach involves the extraction of important features and classification. First, signal components are decomposed to extract the features via the discrete wavelet transform (DWT) method. Principal component analysis (PCA) and the t-distributed stochastic neighbor embedding (t-SNE) algorithm were applied to reduce the dimensions and focus on the most important features. Subsequently, K-means clustering + PCA and K-means clustering + t-SNE were used to divide the dataset into subgroups to reduce the dimensions and focus on the most important representative features of epilepsy. The features extracted from these steps were fed to extreme gradient boosting, K-nearest neighbors (K-NN), decision tree (DT), random forest (RF) and multilayer perceptron (MLP) classifiers. The experimental results demonstrated that the proposed approach provides superior results to those of existing studies. During the testing phase, the RF classifier with DWT and PCA achieved an accuracy of 97.96%, precision of 99.1%, recall of 94.41% and F1 score of 97.41%. Moreover, the RF classifier with DWT and t-SNE attained an accuracy of 98.09%, precision of 99.1%, recall of 93.9% and F1 score of 96.21%. In comparison, the MLP classifier with PCA + K-means reached an accuracy of 98.98%, precision of 99.16%, recall of 95.69% and F1 score of 97.4%.

An automated detection of epileptic seizures EEG using CNN classifier based on feature fusion with high accuracy

BackgroundEpilepsy is a neurological disorder that is usually detected by electroencephalogram (EEG) signals. Since manual examination of epilepsy seizures is a laborious and time-consuming process, lots of automatic epilepsy detection algorithms have been proposed. However, most of the available classification algorithms for epilepsy EEG signals adopted a single feature extraction, in turn to result in low classification accuracy. Although a small account of studies have carried out feature fusion, the computational efficiency is reduced due to too many features, because there are also some poor features that interfere with the classification results.MethodsIn order to solve the above problems, an automatic recognition method of epilepsy EEG signals based on feature fusion and selection is proposed in this paper. Firstly, the Approximate Entropy (ApEn), Fuzzy Entropy (FuzzyEn), Sample Entropy (SampEn), and Standard Deviation (STD) mixed features of the subband obtained by the Discrete Wavelet Transform (DWT) decomposition of EEG signals are extracted. Secondly, the random forest algorithm is used for feature selection. Finally, the Convolutional Neural Network (CNN) is used to classify epilepsy EEG signals.ResultsThe empirical evaluation of the presented algorithm is performed on the benchmark Bonn EEG datasets and New Delhi datasets. In the interictal and ictal classification tasks of Bonn datasets, the proposed model achieves an accuracy of 99.9%, a sensitivity of 100%, a precision of 99.81%, and a specificity of 99.8%. For the interictal-ictal case of New Delhi datasets, the proposed model achieves a classification accuracy of 100%, a sensitivity of 100%, a specificity of 100%, and a precision of 100%.ConclusionThe proposed model can effectively realize the high-precision automatic detection and classification of epilepsy EEG signals. This model can provide high-precision automatic detection capability for clinical epilepsy EEG detection. We hope to provide positive implications for the prediction of seizure EEG.

PredictMed-epilepsy: A multi-agent based system for epilepsy detection and prediction in neuropediatrics

Background and objective: Epileptic seizures are associated with a higher incidence of Developmental Disabilities and Cerebral Palsy. Early evaluation and management of epilepsy is strongly recommended. We propose and discuss an application to predict epilespy (PredictMed-Epilepsy) and seizures via a deep-learning module (PredictMed-Seizures) encompassed within a multi-agent based healthcare system (PredictMed-MHS); this system is meant, in perspective, to be integrated into a clinical decision support system (PredictMed-CDSS). PredictMed-Epilespy, in particular, aims to identify factors associated with epilepsy in children with Developmental Disabilities and Cerebral Palsy by using a prediction-learning model named PredictMed.PredictMed-epilespy methods: We performed a longitudinal, multicenter, double-blinded, descriptive study of one hundred and two children with Developmental Disabilities and Cerebral Palsy (58 males, 44 females; 65 inpatients, 37 outpatients; 72 had epilepsy - 22 of intractable epilepsy, age: 16.6±1.2y, range: 12–18y). Data from 2005 to 2021 on Cerebral Palsy etiology, diagnosis, type of epilepsy and spasticity, clinical history, communication abilities, behaviors, intellectual disability, motor skills, and eating and drinking abilities were collected. The machine-learning model PredictMed was exploited to identify factors associated with epilepsy. The guidelines of the “Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis” Statement (TRIPOD) were followed.PredictMed-epilepsy results: Cerebral Palsy etiology [(prenatal > perinatal > postnatal causes) p=0.036], scoliosis (p=0.048), communication (p=0.018) and feeding disorders (p=0.002), poor motor function (p<0.001), intellectual disabilities (p=0.007), and type of spasticity [(quadriplegia/triplegia > diplegia > hemiplegia), p=0.002)] were associated with having epilepsy. The prediction model scored an average of 82% of accuracy, sensitivity, and specificity. Thus, PredictMed defined the computational phenotype of children with Developmental Disabilities/Cerebral Palsy at risk of epilepsy.Novel contribution of the work: We have been developing and we have prototypically implemented a Multi-Agent Systems (MAS) that encapsulates the PredictMed-Epilepsy module. More specifically, we have implemented the Patient Observing MAS (PoMAS), which, as a novelty w.r.t. the existing literature, includes a complex event processing module that provides real-time detention of short- and long-term events related to the patient’s condition.

An Enhanced Automated Epileptic Seizure Detection Using ANFIS, FFA and EPSO Algorithms

Objectives: Electroencephalogram (EEG) signal gives a viable perception about the neurological action of the human brain that aids the detection of epilepsy. The objective of this study is to build an accurate automated hybrid model for epileptic seizure detection. Methods: This work develops a computer-aided diagnosis (CAD) machine learning model which can spontaneously classify pre-ictal and ictal EEG signals. In the proposed method two most effective nature inspired algorithms, Firefly algorithm (FFA) and Efficient Particle Swarm Optimization (EPSO) are used to determine the optimum parameters of Adaptive Neuro Fuzzy Inference System (ANFIS) network. Results: Compared to the FFA and EPSO algorithm separately, the composite (ANFIS+FFA+EPSO) optimization algorithm outperforms in all respects. The proposed technique achieved accuracy, specificity, and sensitivity of 99.87%, 98.71% and 100% respectively. Conclusion: The ANFIS-FFA-EPSO method is able to enhance the seizure detection outcomes for demand forecast in hospital.

Epilepsy detection in 121 patient populations using hypercube pattern from EEG signals

BackgroundEpilepsy is one of the most commonly seen neurologic disorders worldwide and has generally caused seizures. Electroencephalography (EEG) is widely used in seizure diagnosis. To detect epilepsy automatically, various machine learning (ML) models have been introduced in the literature, but the used EEG signal datasets for epilepsy detection are relatively small. Our main objective is to present a large EEG signal dataset and investigate the detection ability of a new hypercube pattern-based framework using the EEG signals. Material and methodThis study collected a large EEG signal dataset (10,356 EEG signals) from 121 participants. We proposed a new information fusion-based feature engineering framework to get high classification performance from this dataset. The dataset consists of 35 channels, and our proposed feature engineering model extracts features from each channel. A new hypercube-based feature extractor has been proposed to generate two feature vectors in the feature extraction phase. Various statistical parameters of the signals have been used to create a feature vector. Multilevel discrete wavelet transform (MDWT) has been applied to develop a multileveled feature extraction function, and seven feature vectors have been extracted. In this work, we have extracted 245 (=35 × 7) feature vectors, and the most valuable features from these vectors have been selected using the neighborhood component analysis (NCA) selector. Finally, these selected features were fed to the k nearest neighbors (kNN) classifier with the leave one subject out (LOSO) cross-validation (CV) strategy. These results have been voted/fused to obtain the highest classification performance. ResultsIn this work, we have attained 87.78% classification accuracy using voting these vectors and 79.07% with LOSO CV with the EEG signals. ConclusionsThe proposed fusion-based feature engineering model achieved satisfactory classification performance using the largest EEG signal datasets for epilepsy detection.

Deep neural networks for the detection of temporal-lobe epileptiform discharges from scalp electroencephalograms

Although interictal epileptiform discharges (IEDs) are a biomarker of epilepsy on electroencephalograms (EEGs), the manual annotation of IEDs is laborious. Thus, several IED detection methods have been proposed. However, the majority of these methods focus on single or whole cerebral channels. In this study, we examined the effect of channel selection and epoch length on the IED detection of temporal-lobe epilepsy (TLE). We identified two types of deep neural networks for IED detection: convolutional neural networks (CNNs) and long short-term memory (LSTM) networks. We evaluated their performance using the F1-score, a global index of the sensitivity of IED detection, and the proportion of correctly detected IEDs based on scalp EEGs collected from 20 individuals with TLE. We then discovered that selecting EEGs from the affected temporal lobe or hemisphere was associated with a higher F1-score compared with selecting whole cerebral EEGs. In addition, we discovered that selecting a long EEG epoch (3 s) in the CNN model and selecting a short epoch (1.5 s) in the CNN + LSTM model resulted in the highest F1-score. In conclusion, deep neural networks are effective in detecting the TLE IEDs underlying an adequate epoch length when applied to EEGs of interest.

HH model based smart deep brain stimulator to detect, predict and control epilepsy using machine learning algorithm

BackgroundEpilepsy is the most common neurological disorder in the world. To control epilepsy, deep brain stimulation is one of the widely accepted treatment techniques. However, conventional deep brain stimulation technique provides continuous stimulation without optimizing the stimulation parameters, resulting in adverse side effects and unexpected death. Hence, understanding the dynamic behavior of brain neural networks at a cellular level is required for patient-specific epilepsy treatment. Considering the underlying mechanism of a single neuronal shift in the brain neural network, computational model-based techniques have a new face for healthcare, which aims to develop effective medical devices for preclinical investigations. New methodThis paper discusses the design of a Smart Deep Brain Stimulator (SDBS) using the Hodgkin-Huxley (HH) conductance-based cellular model of brain neurons to automatically detect, predict and regulate epilepsy against patient-specific conditions. Epileptic activity is simulated as a spike train of action potential due to sodium and potassium channel conductance variations in the single-neuron HH model. The proposed SDBS consists of three components:- i) seizure detection using bagging and boosting-based ensemble machine learning classifiers, ii) channel conductance prediction using Long Short Term Memory-Recurrent Neural Network (LSTM-RNN) based Deep Neural Network (DNN) for updating model parameters of brain neuron, and iii) model-based intelligent control of epileptic seizure with Nonlinear Autoregressive Moving Average-L2 (NARMA-L2) Controller and Nonlinear Model Predictive Controller (NMPC). ResultsFor effective treatment, improving the overall accuracy and efficiency of SDBS is essential. For epilepsy detection, the ensemble bagging machine learning algorithm provides better accuracy of 92.7% compared to the ensemble boosting algorithm. LSTM-RNN deep neural network model with four layers predicts the variations in channel conductance with Root Mean Square Error (RMSE) of 0.00568 and 0.009081 for sodium and potassium channel conductance, respectively. From the closed-loop performances of SDBS with an intelligent control scheme, it is observed that SDBS with NMPC provides efficient and accurate stimulation with minimum energy consumption. From a stability point of view, SDBS with NMPC provides better stability than SDBS with NARMA-L2 Controller. Comparison with existing methodThe proposed SDBS is designed to generate accurate stimulation pulses for epilepsy patients with specific conditions depending on the neuronal activity of a single neuron. Moreover, it will also adapt to the dynamic condition of epilepsy patients. The existing deep brain stimulator continuously provides stimulation pulses without adapting to the patient’s conditions. ConclusionThe proposed SDBS could provide patient-specific treatment based on sodium/potassium channel conductance variations of brain neurons. It will help increase the use of deep brain stimulation techniques and reduce sudden death. Furthermore, the proposed technique will be extended to neural network models with larger neuronal populations to improve the practical feasibility.

EEG Signal Epilepsy Detection with a Weighted Neighbour Graph Representation and Two-stream Graph-based Framework.

Epilepsy is one of the most common neurological diseases. Clinically, epileptic seizure detection is usually performed by analyzing electroencephalography (EEG) signals. At present, deep learning models have been widely used for single-channel EEG signal epilepsy detection, but this method is difficult to explain the classification results. Researchers have attempted to solve interpretive problems by combining graph representation of EEG signals with graph neural network models. Recently, the combination of graph representations and graph neural network (GNN) models has been increasingly applied to single-channel epilepsy detection. By this methodology, the raw EEG signal is transformed to its graph representation, and a GNN model is used to learn latent features and classify whether the data indicates an epileptic seizure episode. However, existing methods are faced with two major challenges. First, existing graph representations tend to have high time complexity as they generally require each vertex to traverse all other vertices to construct a graph structure. Some of them also have high space complexity for being dense. Second, while separate graph representations can be derived from a single-channel EEG signal in both time and frequency domains, existing GNN models for epilepsy detection can learn from a single graph representation, which makes it hard to let the information from the two domains complement each other. For addressing these challenges, we propose a Weighted Neighbour Graph (WNG) representation for EEG signals. Reducing the redundant edges of the existing graph, WNG can be both time and space-efficient, and as informative as its less efficient counterparts. We then propose a two-stream graph-based framework to simultaneously learn features from WNG in both time and frequency domain. Extensive experiments demonstrate the effectiveness and efficiency of the proposed methods.

Machine Learning Algorithms for Epilepsy Detection Based on Published EEG Databases: A Systematic Review

Epilepsy is the only neurological condition for which electroencephalography (EEG) is the primary diagnostic and important prognostic clinical tool. However, the manual inspection of EEG signals is a time-consuming procedure for neurologists. Thus, intense research has been made on creating machine learning methodologies for automated epilepsy detection. Also, many research or medical facilities have published databases of epileptic EEG signals to accommodate this research effort. The vast number of studies concerning epilepsy detection with EEG makes this systematic review necessary. It presents a detailed evaluation of the signal processing and classification methodologies employed on the different databases and provides valuable insights for future work. 190 studies were included in this systematic review according to the PRISMA guidelines, acquired from a systematic literature search in PubMed, Scopus, ScienceDirect and IEEE Xplore on 1st May 2021. Studies were examined based on the Signal Transformation technique, classification methodology and database for evaluation. Along with other findings, the increasing tendency to employ Convolutional Neural Networks that use a combination of Time-Frequency decomposition methodology images is noticed.

Epileptic Seizure Detection and Prediction in EEGs Using power spectra density parameterization.

Power spectrum analysis is one of the effective tools for classifying epileptic signals based on electroencephalography (EEG) recordings. However, the conflation of periodic and aperiodic components within the EEG may presents an obstacle to epilepsy detection or prediction. In this paper, we explored the significance of the periodic and aperiodic components of the EEG power spectrum for the detection and prediction of epilepsy respectively. We use a power spectrum density parameterization method to separate the periodic and aperiodic components of the signals, and validate their roles in epilepsy detection and prediction on two public datasets. The average classification accuracy of the periodic and aperiodic components for 10 clinical tasks on the Bonn EEG database were 73.9% and 96.68%, respectively, and increases to 98.88% when combined. For 22 patients on the CHB-MIT Long-term EEG database, the combined features achieve an average detection accuracy of 99.95% and successfully predict all seizures with low false prediction rates. We conclude that both the periodic and aperiodic components of the EEG power spectrum contributed to discriminating different stages of epilepsy, but the aperiodic neural activity played a decisive role in classification. This discovery has significant implications for diagnosing epileptic seizures and providing personalized brain activity information to improve the accuracy and efficiency of epilepsy detection.

Revised Tunable Q-Factor Wavelet Transform for EEG-Based Epileptic Seizure Detection.

Electroencephalogram (EEG) signals are an essential tool for the detection of epilepsy. Because of the complex time series and frequency features of EEG signals, traditional feature extraction methods have difficulty meeting the requirements of recognition performance. The tunable Q-factor wavelet transform (TQWT), which is a constant-Q transform that is easily invertible and modestly oversampled, has been successfully used for feature extraction of EEG signals. Because the constant-Q is set in advance and cannot be optimized, further applications of the TQWT are restricted. To solve this problem, the revised tunable Q-factor wavelet transform (RTQWT) is proposed in this paper. RTQWT is based on the weighted normalized entropy and overcomes the problems of a nontunable Q-factor and the lack of an optimized tunable criterion. In contrast to the continuous wavelet transform and the raw tunable Q-factor wavelet transform, the wavelet transform corresponding to the revised Q-factor, i.e., RTQWT, is sufficiently better adapted to the nonstationary nature of EEG signals. Therefore, the precise and specific characteristic subspaces obtained can improve the classification accuracy of EEG signals. The classification of the extracted features was performed using the decision tree, linear discriminant, naive Bayes, SVM and KNN classifiers. The performance of the new approach was tested by evaluating the accuracies of five time-frequency distributions: FT, EMD, DWT, CWT and TQWT. The experiments showed that the RTQWT proposed in this paper can be used to extract detailed features more effectively and improve the classification accuracy of EEG signals.

EpilepIndex: A novel feature engineering tool to detect epilepsy using EEG signals.

Epilepsy is a common neurological disease characterized by seizures. A person with a seizure onset can lose consciousness which in turn can lead to fatal accidents. Electroencephalogram (EEG) is a recording of the electrical signals from the brain which is used to analyse the epileptic seizures. Physical visual examination of the EEG by trained neurologists is subjective and highly difficult due to the non-linear complex nature of the EEG. This opens a window for automatic detection of epileptic seizures using machine learning methods. In this work, we have used a standard database that consists of five different sets of EEG data including the epileptic EEG. Using this data, we have devised a novel 22 possible clinically significant cases with the combination of binary and multi class type of classification problem to automatically classify epileptic EEG. As the EEG is non-linear, we have devised 11 statistically significant non-linear entropy features to extract from this database. These features are fed to 10 different classifiers of various types for each of the 22 clinically significant cases and their classification accuracy is reported for 10-fold cross validation. Random Forest and Optimized Forest classifiers reported accuracies above 90% for all 22 cases considered in this study. Such vast possible clinically significant 22 cases from the combination of the data from the database considered has not been in the literature with the best of the knowledge of the authors. Comparing with the literature, several studies have presented one or few combinations of these 22 cases in this work. In comparison to similar works, the accuracies obtained by the classifiers were highly competitive. In addition, a novel integrated epilepsy detection index named EpilepIndex (IED) is able to differentiate between epileptic EEG and a normal EEG with 100% accuracy.

Prediction of Seizure in the EEG Signal with Time Aware Recurrent Neural Network

The human brain's actions are reflected by the significant physiological data relying on the Electroencephalogram (EEG), which is utilized in the detection of epileptic seizures and the diagnosis of epilepsy. The visual inspection process of a vast quantity of EEG data by any human expert is time-consuming and the judgemental process may vary or be inconsistent among the physician. Hence, an automated process in detection and diagnosis is initiated by utilizing deep learning approaches. The Convolutional Neural Network (CNN) is incorporated to correctly recognize the irregular inter-ictal discharges as non-seizures, but could not detect the ictal state and slower oscillations. To improve the performance of CNN for detecting seizures' ictal state and slower oscillations, Recurrent Neural Network (RNN) is combined with the CNN model. An RNN evokes every processed information via time and it assists in the prediction of time series data. The processed feature in RNN remembers the preceding input information which is Long Short Term Memory (LSTM). The investigational outcome of the proposed Time Aware CNN and Recurrent Neural Network (TA-CNN-RNN) attained effective classification accuracy. The experiments analysis exhibits that the TA-CNN-RNN achieves an accuracy of 89%, 88.6%, and 88.7% on CHB-MIT-EEG, Bonn-iEEG, and VIRGO-EEG databases, respectively compared to the Entropy+LSSVM, LBP+KNN and P-one-class SVM methods for epilepsy detection.

EEG Signal Feature Extraction and Classification for Epilepsy Detection

Epilepsy is a neurological disorder of the central nervous system, characterized by sudden seizures caused by abnormal electrical discharges in the brain. Electroencephalogram (EEG) is the most common technique used for Epilepsy diagnosis. Generally, it is done by the manual inspection of the EEG recordings of active seizure periods (ictal). Several techniques have been proposed throughout the years to automate this process. In this study, we have developed three different approaches to extract features from the filtered EEG signals. The first approach was to extract eight statistical features directly from the time-domain signal. In the second approach, we have used only the frequency domain information by applying the Discrete Cosine Transform (DCT) to the EEG signals then extracting two statistical features from the lower coefficients. In the last approach, we have used a tool that combines both time and frequency domain information, which is the Discrete Wavelet Transform (DWT). Six different wavelet families have been tested with their different orders resulting in 37 wavelets. The first three decomposition levels were tested with every wavelet. Instead of feeding the coefficients directly to the classifier, we summarized them in 16 statistical features. The extracted features are then fed to three different classifiers k-Nearest Neighbor (k-NN), Support Vector Machine (SVM), and Artificial Neural Network (ANN) to perform two binary classification scenarios: healthy versus epileptic(mainly from interictal activity),and seizure-free versus ictal. We have used a benchmark database, the Bonn database, which consists of five different sets. In the first scenario, we have taken six different combinations of the available data. While in the second scenario, we have taken five combinations. For Epilepsy detection (healthy vs epileptic), the first approach performed badly. Using the DCT improved the results, but the best accuracies were obtained with the DWT-based approach. For seizure detection, the three methods performed quite well. However, the third method had the best performance and was better than many state-of-the-art methods in terms of accuracy. After carrying out the experiments on the whole EEG signal, we separated the five rhythms and applied the DWT on them with the Daubechies7(db7) wavelet for feature extraction. We have observed that close accuracies to those recorded before can be achieved with only the Delta rhythm in the first scenario (Epilepsy detection) and the Beta rhythm in the second scenario (seizure detection).

DSCNN-LSTMs: A Lightweight and Efficient Model for Epilepsy Recognition.

Epilepsy is the second most common disease of the nervous system. Because of its high disability rate and the long course of the disease, it is a worldwide medical problem and social public health problem. Therefore, the timely detection and treatment of epilepsy are very important. Currently, medical professionals use their own diagnostic experience to identify seizures by visual inspection of the electroencephalogram (EEG). Not only does it require a lot of time and effort, but the process is also very cumbersome. Machine learning-based methods have recently been proposed for epilepsy detection, which can help clinicians make rapid and correct diagnoses. However, these methods often require extracting the features of EEG signals before using the data. In addition, the selection of features often requires domain knowledge, and feature types also have a significant impact on the performance of the classifier. In this paper, a one-dimensional depthwise separable convolutional neural network and long short-term memory networks (1D DSCNN-LSTMs) model is proposed to identify epileptic seizures by autonomously extracting the features of raw EEG. On the UCI dataset, the performance of the proposed 1D DSCNN-LSTMs model is verified by cross-validation and time complexity comparison. Compared with other previous models, the experimental results show that the highest recognition rates of binary and quintuple classification are 99.57% and 81.30%, respectively. It can be concluded that the 1D DSCNN-LSTMs model proposed in this paper is an effective method to identify seizures based on EEG signals.

Epilepsy Detection Method Based on the Time-gated Feature Network

Epilepsy is a nervous system disease, which is caused by abnormal discharge of brain neurons. The clinical manifestations are generalized seizures, clonus, loss of consciousness, and shock. An electroencephalogram (EEG) can accurately capture the changes in EEG activities. Therefore, EEG signals are used to detect seizures. In this paper, an epilepsy detection model based on a time-gated feature network (TFGN) is proposed. Firstly, the original EEG signal is preprocessed, and the preprocessed signal is sent into the TFGN detection model which integrates feature extraction, feature selection, and classification to obtain the detection results of epilepsy. Through the verification of data from different ages and channels, the detection accuracy of the TFGN detection model is higher than that of the traditional detection model, and the validity and comprehensiveness of the TFGN detection model are verified.

Evaluating the Window Size’s Role in Automatic EEG Epilepsy Detection

Electroencephalography is one of the most commonly used methods for extracting information about the brain's condition and can be used for diagnosing epilepsy. The EEG signal's wave shape contains vital information about the brain's state, which can be challenging to analyse and interpret by a human observer. Moreover, the characteristic waveforms of epilepsy (sharp waves, spikes) can occur randomly through time. Considering all the above reasons, automatic EEG signal extraction and analysis using computers can significantly impact the successful diagnosis of epilepsy. This research explores the impact of different window sizes on EEG signals' classification accuracy using four machine learning classifiers. The machine learning methods included a neural network with ten hidden nodes trained using three different training algorithms and the k-nearest neighbours classifier. The neural network training methods included the Broyden-Fletcher-Goldfarb-Shanno algorithm, the multistart method for global optimization problems, and a genetic algorithm. The current research utilized the University of Bonn dataset containing EEG data, divided into epochs having 50% overlap and window lengths ranging from 1 to 24 s. Then, statistical and spectral features were extracted and used to train the above four classifiers. The outcome from the above experiments showed that large window sizes with a length of about 21 s could positively impact the classification accuracy between the compared methods.