The main purpose of the study is to analyze nature, features and role of franchising in commercialization of intellectual property. Authors proved that franchising mechanism can lead to high returns from minimal risks and increase the level of innovative development of national economy. Franchising investigated as a form of business organization that meets the needs of today's consumer markets. The nature and role of franchising in modern globalized marketplace are discovered. Peculiarities of commercialization of the results of creative intellectual activity are analyzed. The history of franchising is considered. Analysis of the economic nature of franchising and main approaches to its definition as an economic category are generalized. The current state of the Ukrainian franchising market is studied. Theoretical model of interaction between franchisor and franchisee in the intellectual property market is considered. Examples of the most successful modern Ukrainian franchises are considered. Advantages of franchising as an effective business model and mechanism of intellectual property commercialization are determined. In the context of the commercialization of intellectual property, franchising provides certain benefits for both parties to the franchise agreement and, at the same time, creates additional risks. By entering into a franchise relationship, the owner of intellectual property rights risks losing the business reputation and trust of consumers through the production and sale of low-quality products to the franchisee. Conducted analysis demonstrated that franchising market grew by 18% compared to the same period last year. At the same time, the Ukrainian franchise market remain quite diversified. Enterprises operate in various fields: catering, services, retail trade. Authors proved that in a post-industrial economy, intellectual property becomes a major factor of production, and intellectual property relations are developing rapidly. Under these conditions, franchising forms an effective mechanism for the commercialization of an intellectual product and creates the preconditions for increasing the competitiveness of economic entities in the conditions of post-industrial transformations.