ABSTRACT Computed tomography (CT) imaging was confirmed as one of the important evolving radiological features of disease diagnosis. In this work, we propose an image filtering method for CT images that fuses the spatial and the transform domain. Filters in the transform domain work well in restoring low-contrast details that are usually smoothed by spatial domain filters. The new filter is based on a modified anisotropic diffusion approach combined with the phase congruency (PC) feature. The PC feature is a scale-invariant compared to the classical gradient, where weak edges are usually omitted and undetected with gradient-based feature detectors. This feature is incorporated in the diffusion function to enhance image edges while eliminating noise and texture background. In a further step, a U-net convolutional network is used to segment the lung-infected area. Comparative tests and results show the efficiency of our method, which permits to enhance image features while removing noise perfectly.