In this study, swimming was performed for 12 weeks, 3 times a week, once for 60 minutes for normal middle-aged women living in P city. Health physical fitness, blood lipid and stress hormone were measured and analyzed using SPSS Ver.21.0 statistical program. The result was as follows.<BR> 1. Within the group, muscle endurance, flexibility, and lean mass significantly increased and body fat percentage significantly decreased in the exercise group. There was no significant difference in muscle strength, muscular endurance, flexibility, cardiorespiratory endurance, body fat percentage, and lean mass in the control group. There was no significant difference in all items between groups.<BR> 2. Within the group, there were no significant differences in all items in the exercise group. In the control group, only high-density lipoprotein cholesterol showed a significant decrease, and there was no significant difference in total cholesterol, triglyceride, and low-density lipoprotein cholesterol. <BR> 3. Within the group, there was no significant difference in both the exercise group and the control group, and there was no significant difference in all items between groups.<BR> Summarizing the above results, regular swimming exercise had a significant effect on health, but did not significantly effect on blood lipids and stress hormones. Regular and continuous aerobic exercise, such as swimming, proper personal fitness level, has a positive effect on preventing the increase of blood lipids and stress hormones. In the future, it is expected that many follow-up studies on changes in blood lipids and stress hormones will be studied for safe and systematic exercise intensity setting.