Development Of Human Beings Research Articles

Zinc Nutritional Status in Patients with Cystic Fibrosis.

Background: Zinc is an essential nutrient for all forms of life and its deficiency affects the normal growth and development of human beings. Objective: The main aim was to investigate zinc nutritional status by serum zinc concentration (SZC) and dietary zinc intake and their association in cystic fibrosis (CF) patients. Methods: A cross-sectional study was conducted in CF patients. Anthropometric measurements and respiratory and pancreatic tests were conducted. Hypozincemia was determined by SZC while using atomic absorption spectrophotometry and dietary zinc deficiency by prospective 72-h dietary surveys. Results: Mean SZC (87.2 ± 16.7 μg/dL) and dietary zinc intake (97 ± 26.9% Dietary Reference Intake) were normal. Three of 17 patients with CF (17.6%) had hypozincemia and four (23.5%) had a dietary zinc deficiency. No patient with dietary zinc deficiency had hypozincemia. A positive and significant association was observed between SZC and Z-score of BMI-for-age (p = 0.048) and weight-for-height (p = 0.012) and between dietary zinc intake and energy intake (EI, p = 0.036) and Z-score of weight-for-high (p = 0.029). Conclusion: SZC was associated with the nutritional status, expressed as BMI (Body Mass Index) and weight-for-height Z score, and dietary zinc intake with EI and weight-for-height Z-score. No patient with hypozincemia had dietary zinc deficiency. This situation should alert us to a marginal zinc deficiency and it may explain why there were no overlapping cases between the two groups. We suggest that probably 41% of the cases in this study would be at elevated risk of zinc deficiency and a zinc supplementation may be considered.

The principles of sports training as a methodology alternative in the cognitive development of the human being

This research focuses on establishing a relationship between the principles of sports training and the processes of cognitive development of human beings whose general objective lies in the design of a methodological alternative. In this sense, sports training are understood as one of the most widely disseminated and researched topics on an international level in the field of sports, where there is a wealth of theories and trends that help to base and investigate human development processes; hence it is understood as one of the central categories of this work. In this regard, Bautista [1] calls us to recognize sports training as a pedagogical model in the educational field. Therefore, it is very important to establish as fundamental parameters the classification of training principles, divided into two large blocks by Muñoz and Soto [2], the Biological principles and the pedagogical principles. In this thread, it is important to highlight the category where the above is based, cognitive development understood as the axis that implies the identification of changes that influence the different representation structures that operate in the cognitive system and that point to the rediscovery and reconstruction of new knowledge Hence, the guiding question raises: What is the relationship between the principles of sports training and the processes of cognitive development in the human being? Thus, the methodological route of the present study responds to the interpretative paradigm, specifically it is oriented from the qualitative design. Therefore, it exposes an approach to the establishment of possible relationships between the categories of analysis.

FIRST LANGUAGE ACQUISITION OF A THREE YEARS OLD CHILD: AN ANALYSIS OF PHONOLOGICAL COMPONENT (A CASE STUDY)

The process of language acquisition undergone by each child in the world is more and less similar. This is because language is universal in which it is acquired through all language components namely phonology, semantics, and pragmatics. The component of phonology is more related to human neuro-biology. The process of sound produced is genetic and human biological development is not similar. Hence, the language development of human beings is not exactly the same. This paper explores first language acquisition particularly on the phonological component of a three years old child named Andi. The data is the transcripts of dialog taken from causal chit chats with the participant. A qualitative method is used to analyze the data. The findings reveal that the participant acquired vocal sounds of /a/, /i/, /u/, /o/, /e/ and consonant sounds of /p/, /b/, /m/, /t/ more dominant compared to others. He never produced /k/ consonant, fricative [s] and [j]. However, he produced nasal consonants of [m], [n], and [ɳ]. The participant also substituted omitted a few sounds. This might happen because his speech articulation has not developed well yet or genetic factor does not allow him to do so.

Perfil de responsabilidad social empresarial del sector solidario en Ibagué, Colombia

Resumen: El presente artículo de investigación muestra la elaboración del perfil de responsabilidad social empresarial del sector solidario en Ibagué, Colombia, sector de gran importancia debido a su enfoque sin ánimo de lucro y a la aplicación de prácticas enfocadas en el desarrollo integral del serhumano. El enfoque es mixto, emplea el análisis de correspondencia como técnica estadística y la descripción de resultados como complemento cualitativo. La recolección de información se realizó a través de un cuestionario aplicado mediante entrevista a empresas del sector solidario en Ibagué. Los resultados permiten establecer las fortalezas y debilidades del sector en materia de responsabilidad social, el nivel de implementación de actividades socialmente responsables y el compromiso de las empresas solidarias con sus colaboradores, asociados y grupos de interés.

A CONCEPTUAL PLOT CENTERED ON CURRIUCLUM INSPIRED BY THE PEDAGOGY OF THE OPPRESSED

In recent decades, curriculum has found itself in an arena of dispute as it deals with decisions related to the education and development of human beings. To speak of curriculum entails confronting the question: What education do we want and need for the society in which we live? This text aims to present a critical analysis centered on the concept of curriculum, by way of a freirean conceptual plot constructed with reference to the Pedagogy of the Oppressed. It is a theoretical reflection that seeks to offer contributions to teaching and research in the subarea of Curriculum. The option for Freirean epistemology has been made on the basis that it takes dialogue as an ethical-political-gnosiological presumption and utopia as a horizon for social transformation that is possible to reach. An excursion through the work of Paulo Freire, taking the Pedagogy of the Oppressed as a base, made it possible to select categories that are connected and allowed for the composition of an original and comprehensive conception of the curriculum construct, through the methodological interweaving of the following categories: critical reflection on practice, languages, dialogue, participation and transformation. The construction of this Freirean conceptual plot, a theoretical-methodological resource for teaching and research, lends itself to the fields of curricular theory and development and can support discussions and curricular practices in every modality and level of teaching.

A MODEL INTEGRATING CULTURAL DIVERSITY EDUCATION INTO THE ACCOUNTING CURRICULUM IN HIGHER INSTITUTION

Education is one of the elements of character formation and development of human beings. Cultural diversity education is a conscious effort to develop personality inside and outside school to learn about the different kinds of social status, race, ethnicity, religion in order to create a good personality in dealing with issues of cultural diversity. In this article we propose a framework of cultural diversity education in academic program for accounting students. The education emphasizes knowledge of and interaction with other cultures and ethnicities.Cultural diversity education and understanding of the relativity of cultural differences is a our growing sense and awareness of the importance of respect, recognize and accept the diversity that already exist

Smart photoactive soft materials for environmental cleaning and energy production through incorporation of nanophotocatalyst on polymers and textiles

Energy and environment are key issues for the sustainable development of human beings and are also the current and long‐term focuses of scientific research. New energy and environmental technologies in combination with polymer and textile science work to create many additional functions for conventional polymers and fabrics. Therefore, some novel technical polymers and textiles, such as photovoltaic and photocatalytic polymers and textiles, have begun to emerge. Generally, light‐activated chemicals, materials, or processes that are produced or enabled by light and the agent absorbing light starting a photochemical alteration in the system is nominated as photocatalyst. This review firstly introduces the different photoactive materials, their classifications, and degradation mechanism. Then, inorganic semiconductor nanoparticles were selected as the best candidate for the application in soft materials. Finally, a detailed study was provided on both preparations of photoactive soft materials using metal oxide semiconductors and their advantages and applications. This paper will be more helpful for the scientists working in the field of photoactive soft materials.

A new methodology for the determination of silicon in plants by wavelength dispersive X‐ray fluorescence

Silicon is an important element for plants at their structure and physiology and plays an important role in bone mineralization and soft tissue development in human beings. Furthermore, its determination is being requested more frequently due to nutritional requirements. However, the methods found in the literature to determine silicon in this type of samples require a sample preparation step, which makes them time‐consuming and provides high uncertainties.In this paper, a method for the determination of silicon in plants by wavelength dispersive X‐ray fluorescence (WD‐XRF) spectrometry has been developed. Horsetail (Equisetum arvense L.) and nettle leaf (Urtica dioica) have been used as a source of silicon due to its medical use. Sample preparation involved calcining the sample at 700°C and preparing fused beads from the calcined sample. Calibration standards for WD‐XRF measurement were prepared by mixing certified reference materials and chemical products to reproduce the samples matrix. The linear range for silicon concentration ranges from 6 to 55 wt% SiO2. The validation of the method was performed measuring a reference material (NCS DC73349 Bush branches and leaves) and comparing the results obtained by WD‐XRF with those obtained by an independent method by atomic absorption spectrometry.The developed methodology is rapid and accurate, provides low uncertainties, and is environmentally friendly, as it does require the use of less hazardous reagents.

The Education Assessment Capacity Structure of Primary Teachers in Vietnam

Education assessment capacity is considered to be indispensable for teachers at all levels. However, there are currently many difficulties in assessing this capacity, especially for primary teachers when there is a change in assessing students. In this report, we would like to suggest a education capacity assessment structure for primary teachers and to demonstrate such structure through a survey of primary teachers' assessment capacity in Vietnam. Survey results show that the education assessment capacity structure consists of 6 component competencies which suitable for primary teachers in Vietnam. And, the report also points out that Vietnamese primary teachers' education assessment capacity in Vietnam is currently evaluated at a fairly good level.
 Keywords
 Education assessment capacity structure, primary teachers
 References
 1. American Federation of Teachers & National Council on Measurement in Education (1990), Standards for Teacher Competence in Educational Assessment of Students, Washington DC.2. Dinh Quang Bao (2017), Fostering teachers to meet professional standards in the context of general education renovation, The summary record of a scientific conference: Rationale and practice of the professional capacity of teachers and educational administrators in the Northwest, Page 75-84.3. Ministry of Education and Training (2007), Professional standards for primary teachers, issued together with Decision No. 14/2007/QD-BGD dated 04 May 2007.4. Ministry of Education and Training (2010), Charter of primary schools, issued together with Circular No. 41/2010/TT-BGDDT dated 30 December 2010.5. Ministry of Education and Training (2016), Amending and supplementing some articles of the Regulations on the assessment of primary students, issued with Circular No. 22/2016/TT-BGDDT, dated 22 September 2016. 6. Canada Education Assosciation Joint Advisory Committee (1993), Principles for Fair Student Assessment Practices for Education in Canada, Edmonton, Alberta: Emonton.7. Nguyen Duc Chinh (2017), How do principals do to successfully lead teachers to develop student competencies, The summary record of a scientific conference: Rationale and practice of the professional capacity of teachers and educational administrators in the Northwest, Page 20-28.8. Nguyen Huu Chau (2008), Educational quality- Theoretical and practical issues, Vietnam Education Publishing House Limited Company.9. Bui Van Hue (1997), Primary psychology textbook, Vietnam Education Publishing House Limited Company, 1997, Page 33-91.10. Tran Thi Huong, Cao Xuan Hung (2017), Student assessment capacity building activities for primary teachers in District 3, Ho Chi Minh City, Ho Chi Minh City University of Education, Journal of Science , Volume 14, No. 10 (2017), Page 63-71.11. Nguyen Cong Khanh (2015), Student assessment based on the capacity-based approach. The summary record of an international conference: “Psychology and Pedagogy in the development of human beings in Vietnam”. University of Education Publishing House, Page 688-695.12. Nguyen Cong Khanh, Nguyen Vu Bich Hien (2013), Proposing the education assessment capacity framework for high school teachers, The summary record of READ conference, Hanoi.13. Nguyen Thi My Loc (2003), 21st century teachers: Being creative and effective, Journal of Teaching and Learning Today (7), Hanoi.14. Duong Thu Mai (2012), Studying and suggesting of a common capacity framework for the education assessment, The summary record of READ conference, Hanoi.15. Duong Thu Mai (2016), Forms of assessing modern education and methods of assessing the learning capacity of high school students in Vietnam, VNU Journal of Science: Educational research, Volume 32, No. 1 (2016) Page 51-61.16. Pham Duc Quang (2012), Some core components in the general education programs are built based on the competency building orientations, The summary record of a conference: The general core competency system of students for general education programs in Vietnam, Hanoi, Page 36- 49.17. Pham Hong Quang (2013), Development of teacher training programs, theoretical and practical issues, Thai Nguyen Publishing House.18. Nguyen Kim Son, Le Ngoc Hung, Nguyen Quy Thanh, Ta Thi Thu Hien, Pham Van Thuan, Duong Thi Hoang Yen (2018), Education Renovation in Vietnam: From the perspective of teachers, The summary record of an international conference: New trends in education, Page 42-57.19. Stronge, J. H. (2004), Qualities Of Effective Teacher, Le Van Canh translate, Vietnam Education Publishing House.20. Hoang Thi Tuyet (2004), Training of the education assessment capacity: A practical perspective, The summary record of a conference: The role of inspection and assessment activities in the renovation of education in Vietnam, Page 96-103.

An Examination of the Value of Individual Social Responsibility and Quality in the New Era

With the socialism with Chinese characteristics has entered a new era, which marks a new starting point, China has embarked on a new journey and shouldered a new mission. In this regard, it is the inevitable demand for the modernization of the new era to cultivate the quality of individual social responsibility. The quality of individual social responsibility is the basic requirement for the comprehensive development of human beings, the inevitable demand of social governance modernization, and also the natural demand of ideological and political education in the new era. A rational examination of the value of individual social responsibility quality is of great significance to the construction of spiritual civilization in China in the new era.

Evolutionity – A New Age of Humanity: On the Concept of Human Evolution by Hoene-Wroński

In this article, I present the concept of human evolution by Jozef Hoene-Wronski. I believe that his ideas are still an unexplored resource which can lead us to the better understanding of the evolution of humanity and of our human destiny. Hoene-Wronski has boldly challenged the deterministic picture of the world emerging from modern science and has derived human evolution from the moral and rational development of human beings. I follow closely his discussion of human evolution and describe its seven stages. Further, I argue that the case of human evolution is strongly supported by new scientific theories, especially by quantum theory and the novel perspectives that it opens for humankind. I end my article with the conclusion that the insights on human evolution derived from the Hoene-Wronski’s writings and from new scientific theories can guide us to the new politics based on the awareness of true human identity – the politics, which can overcome old divisions among humankind and conflicts derived from them. Ultimately, they can initiate evolutionity – the new evolutionary epoch, which will replace modernity and postmodernity.

The -31 G/C promoter gene polymorphism of surviving in Turkish colorectal cancers patients

Survivin (also known as birc5) is the first protein discovered among the apoptosis-regulating gene family referred to as inhibitor of apoptosis proteins (IAPs). It is expressed and controlled during cellular differentiation and development in human beings. Survivin expression has been shown in a number of cancers and has been associated with cancer development. In our study, we compared with blood samples as our control and normal- tumoural tissue samples, which obtained from the same tissue of 100 cases diagnosed with colorectal cancer, at Department of Pathology, Istanbul University. The present study employed PCR-RFLP to identify the -31 G/C polymorphism in the promoter region of the survivin gene. Distribution of the survivin polymorphism was compared between control and tumoural tissue samples using the chi-square test. Comparison of all samples revealed that there was significant difference in distribution of survivin promoter -31G/C between control group and tumour and normal tissue of the patient group (p<0.05). When genotypes of the control and tumour tissues were compared according to gender, there was no statistically significant difference in the distribution of survivin promoter -31G/C in females p=0.420 or males p=0.309. A significant difference was seen in distribution of C allele in tumour tissue compared to normal tissue.

Die Sprache der Objekte

Abstract Material objects play a central role in the development of human beings. The following paper reconstructs their importance in the testimony of a holocaust survivor. Materials play an important role in the formation of the lifeworld. In a concentration camp, they often gain an unexpected existential importance. According to the context clothes, wood, food, earth change their meaning for the detainees. The kind of clothes corresponds with the type of camp and may be an indicator for the chances to survive. In a concentration camp, a piece of wood can either be used to heat a room in extreme cold and contribute to the survival of a detainee or to beat and torture a prisoner. Finally, the materiality of food is experienced as a prerequisite of life; its absence is a threat, its availability a hope for survival.

Abstract B062: Proteomic characterization of the secretome from prostate cancer and bone progenitor cell coculture

Abstract Prostate cancer (PCa) is one of the most frequent sites of primary tumor development in human beings. PCa tumor cells tend to disseminate to and form metastatic lesions in the bone. Given the evident prevalence and clinical significance of bone metastases, unraveling the mechanisms exploited by cancer to form these destructive lesions is of critical interest. This is partly due to the fact that the metastatic cascade encompasses many rate-limiting steps demanding tumor cells to employ new mechanisms at each stage. Our work aimed at evaluating which soluble factors could mediate the chemical crosstalk between PCa cells and bone progenitor cells. For this purpose, we used coculture transwell systems of PC3 (human PCa cells) with the preosteoclastic Raw264.7 or preosteoblastic MC3T3 cell lines (murine cells), where cells shared the culture media (CMs) without physical contact for 24h. We employed mass spectrometry—nanoLC-MS/MS(Orbitrap) —for the secretome analysis of the CMs. The obtained spectra were analyzed with the Proteome Discover Software and compared with both human and murine protein databases. Results highlight a differential secretome profile released to the CM when tumor cells are grown in coculture compared to controls. These results could potentially explain the altered mRNA expression levels assessed by RTqPCR in PCa cells growing in coculture, displaying significant upregulation for HO-1 ANXA2, ANXA2R, OPG, and PTHrP (p&amp;lt;0.05). Of note, coculture secretomes showcase highly bone-associated proteins released by tumoral cells such as periostin, cartilage oligomeric matrix protein, OPN, BMP and ILGF-II, IL-7, FGF, Mx-1—involved in prostate carcinogenesis—compared to controls, evidencing a misregulated microenvironment. These results may offer a better understanding of the molecular affinity between PCa cells and the bone microenvironment, allowing the improvement of PCa patient prognosis Citation Format: Nicolás Anselmino, Alejandra Páez, Sofía Lage Vickers, Javier Cotignola, Pía Valacco, Geraldine Gueron, Elba Vázquez. Proteomic characterization of the secretome from prostate cancer and bone progenitor cell coculture [abstract]. In: Proceedings of the AACR Special Conference: Prostate Cancer: Advances in Basic, Translational, and Clinical Research; 2017 Dec 2-5; Orlando, Florida. Philadelphia (PA): AACR; Cancer Res 2018;78(16 Suppl):Abstract nr B062.

Talking about Urban Ecological Environment and Sustainable Development

Ecological environment is an important guarantee for the survival and development of human beings. It has a very important role and impact on human development. The process of human development has brought about serious damage to the ecological environment. This is not only detrimental to the sustainable development of the ecological environment, but also has brought great constraints on the development of the city. Therefore, it is necessary to strengthen the management of the ecological environment. To ensure the sustainable development of the ecological environment. This article not only analyzes the ecological environment problems faced by China’s urban development, but also further elaborates the sustainable development of urban ecological environment.

Louis Lavelle i problemy ponowoczesności

The article presents and analyses the philosophical thought of Louis Lavelle, a representative of the French “Philosophy of Spirit” and a precursor of the philosophy of being. The ideas of Louis Lavelle are confronted and compared with the thought of M. Heidegger or J.-P. Sartre, as well as with the theses of postmodern thinkers, such as M. Foucault and R. Rorty. While all these philosophers reject the Enlightenment domination of Reason, the distinguishing feature of Lavelle’s philosophy is an optimistic vision of human participation in the dynamic being which constitutes the highest value.In the paper it is indicated that the axiology of Louis Lavelle might be a major contribution to the contemporary philosophical discourse. The affirmation of being, which is the basis of his axiology and metaphysics, opens new perspectives for the development of human beings and for the appreciation of values in individual life and within the society. This conception might be a good starting point for refuting the postmodern diagnosis and for developing a new axiology based on the participation in dynamic being, which is a foundation for all values.

AACVOX: mobile application for augmentative alternative communication to help people with speech disorder and motor impairment

AbstractIntroduction: Communication is a fundamental element for the development of human beings, promoting their coexistence in society. However, changes in muscle tone, associated with cerebral palsy (CP), among other conditions, cause phono-articulatory dysfunctions hindering speech capabilities. Although there are resources for augmentative and alternative communication (AAC), most of them do not completely satisfy the needs of individuals with motor impairment. Therefore, this study proposes a tool based on mobile technology for AAC, which can be adapted to the characteristics of the motor limitations of CP users. Methods Mobile system development was conducted employing user-centered design and development methods. Functions were developed allowing the communication of phrases through pictographic resources and a mechanism of speech synthesis, that can be customized according to specific communication needs. To validate this system, 20 CP volunteers with speech difficulties and motor impairment were recruited from two institutions in the State of Sao Paulo, Brazil. They operated the system following a pre-defined test protocol, and they answered a system usability scale (SUS) questionnaire, to rate the ease of learning, memorization, efficiency, occurrence of runtime errors, and the level of user satisfaction. Results The results showed a score of 85.85 ± 2.28 above the average SUS scale, for each one of the quality components assessed by the volunteers. Conclusion The developed software is user-friendly, representing a new option for AAC, and is customized according to the communication needs of people with speech disorder and motor impairment.

Frequency of XRCC1 exon 10 G&gt;A gene polymorphism in the Saudi Arabian Population: Inter-individual study from different ethnic groups

Introduction: The failure of DNA repair genes is the main reason for cancer development in human beings. The normal X-ray repair cross-complementing Group1 (XRCC1) gene play a key role in base excision repair (BER) pathway. The occurrence of XRCC1 exon 10 G>A polymorphism varies in different ethnic groups and the data on the allelic distribution of the same is lacking in Saudi Arabian population. The objective of the current study was to delve deep into the documented studies and analyze the frequency of genetic polymorphism XRCC1 exon 10 G>A in Saudi Arabian population and further do the comparison with other ethnic groups of the world. Methods: PUBMED (Medline), web-databases was searched for the required epidemiological studies of different ethnic group. Results: The frequency of XRCC1 exon 10 variant allele (A) was found to be 22.3%. Further this frequency was compared with various others ethnic groups and a significant difference was found for Thailand (p=0.001), Iran (p=0.025), Japan (p=<0.001), North India (p=<0.001), Poland (p=0.010), France (p=0.001), Norway (p=<0.001), USA (p=<0.001), Pakistan (p=<0.001), Spain (p=<0.001), Belgium (p=<0.018), Australia (p=<0.001), and Portuguese (p=<0.045) population. Conclusions: The overall results of this study suggest that frequency of this DNA repair genes demonstrates distinctive pattern in Saudi Arabia population, which might be possible because of ethnicity variation. This could assist in high-risk screening of humans exposed to environmental carcinogens and cancer predisposition in different ethnic groups.

REMOTE SENSING MONITORING OF WETLAND OF SANYA AND LINGSHUI IN HAINAN PROVINCE, BASED ON GF DATA

Abstract. Wetland is an important land and natural resources with many functions. It is closely related to the survival, reproduction and development of human beings, as well as one of the most important living environments of human beings. Hainan Province, which is located in the northern edge of the tropics with the tropical monsoon climate and covers a variety of wetland types. In this paper, in order to investigate the change of wetland distribution and the variations of area in study region, the remote sensing data of GF-1 and GF-2 from 2009 to 2015 were used. The method used in this study was automatic information extraction and human-computer interaction. The wetland types in study area mainly was divided into three level-1 classes, including coastal wetland, river wetland and lake wetland, and was also divided into eight level-2 classes at the same time. The results showed that the total area of wetland increased 9.13 km2 in study area from 2009 to 2015, in which the area of constructed wetland increased 6.29 km2, the natural wetland increased only 2.83 km2. The area of natural wetland has not changed much, but its proportion has been reduced. This reflected that the wetland in the research area has been more artificially intervened since 2009, which caused the increasing of the area of constructed wetland. As the wetland resources can coordinate the sustainable benefit of the society, the protection of natural wetland should be strengthened and valued.

Medienanthropologie

This article analyses the role of media for human development and education and the importance of anthropology for the understanding of media. It focuses the role of media for the social and cultural development of human beings and for the performative use of media. It demonstrates to what degree media are prerequisites for our understanding of the world and of ourselves and emphasizes the importance of the new media for the ›digital natives‹.