The lightest neutralino (χ˜10) is a good dark matter (DM) candidate in the R-parity conserving minimal supersymmetric Standard Model. In this work, we consider the light Higgsino-like neutralino as the lightest stable particle, thanks to a rather small Higgsino mass parameter μ. We then estimate the prominent radiative corrections to the neutralino-neutralino-Higgs boson vertices. We show that for Higgsino-like χ˜10, these corrections can significantly influence the spin-independent direct detection cross section, even contributing close to 100% in certain regions of the parameter space. These corrections, therefore, play an important role in deducing constraints on the mass of the Higgsino-like lightest neutralino DM, and thus the μ parameter. Published by the American Physical Society 2024