Abstract Issue/Problem In Serbia, 12,8% of younger adults and 16,5% of sixteen years old adolescents have tried some of the illegal drugs. “Creative workshop with schoolchildren on prevention of drug abuse” program was developed as a part of National strategy against drug abuse, aiming to improve capacities of teachers and children in primary schools. Description of the practice Program based on educational approach “Shared learning in action” changes traditional school roles, transforming teachers into facilitators, allowing full expression of children’s ideas, thus enhancing development of their emotional intelligence. Children’s research about drugs mobilizes an extensive list of supporters in gathering relevant information: health workers, police, psychologists, teachers, parents and media. This information is then shaped into a variety of products with strong public health messages: songs, posters, comics, brochures, short plays and videos. Results Since 2010, around 450 teachers and nearly 7000 children in 115 Belgrade primary schools were included. Children’s knowledge about drugs has an upturn of over 50%, concurrently with improvement of their teamwork skills, self-confidence, research and creative potentials. Both teachers’ and children’s evaluation grades show a high level of satisfaction with the program. Lessons This program is an example of cooperation between educational and health sector, followed by a well implemented monitoring system and quality improvement. Its universal and flexible approach made it a part of official curricula in several schools. It was acknowledged as good practice by the Institute for improvement of education in 2012 and The City of Belgrade in 2018. Since 2014, the program has its Facebook page “Tvoje znanje menja sve”. Key messages High grade of children autonomy, supported by teachers and community, makes the learning process amusing and effective. Program achievements demonstrate its potential for systemic implementation to a wide range of public health topics.