Conflicts between large сarnivores and humans have been common in mountainous regions, with the Carpathians being particularly affected. Recently, interest among researchers and wildlife managers in studying and managing these conflicts has grown significantly. Unfortunately, the coexistence between humans and wildlife and its implications for nature and society have been largely overlooked in Ukraine. This study analyzed conflicts between large carnivores (Canis lupus, Ursus arctos and Lynx lynx) and farmers/beekeepers within designated model territories in the Ukrainian Carpathians, focusing on the effectiveness of conflict prevention strategies implemented between 2018 and 2023. Among the stakeholders analyzed, 79.0% were farmers (livestock owners) and 21.0% were beekeepers. It was observed that 73.0% of farms and apiaries experienced conflicts with large carnivores during the study period; incidents included 64.8% with wolf attacks, 31.3% with bear attacks, and 24.2% with lynx attacks. Notably, conflicts involving livestock owners and large carnivores decreased nearly fivefold, from 54.9% in 2018 to 11.0% in 2023. Similarly, bear-related conflicts among beekeepers nearly halved, from 29.2% to 16.8%. The adoption of electric fences significantly increased among farms and apiaries from none to 33.9%, and the proportion of farmers using dogs for livestock protection without experiencing large carnivore conflicts rose from 3.3% to 20.9%. These pilot findings highlight the effectiveness of such measures in reducing conflicts and improving coexistence quality. The results provide valuable insights into the structure, dynamics, and spatial distribution of conflicts in the Ukrainian Carpathians, underscoring their importance for the conservation of rare species and the implementation of effective management strategies for wild animal populations, sustainable farming, and habitat conservation in regions inhabited by large carnivores. An integrated approach that considers the needs of both human communities and wildlife, involving collaboration among scientific bodies, public organizations, and government entities at various levels, is crucial for devising and executing effective conflict management strategies in diverse landscapes.