The nuclear fusion reactor ITER (International Thermonuclear Experimental Reactor) foresees a Pressure Suppression System (PSS) in order to manage a Loss of Coolant Accident (LOCA) in the Vacuum Vessel (VV). A LOCA scenario is postulated to occur in the cooling systems of plasma facing components. The Vacuum Vessel Pressure Suppression System (VVPSS) has a key safety function because a large internal pressure in the VV could lead to a breach of the primary confinement barrier.Steam condensation would occur in ITER at sub-atmospheric pressure, differently than the applications in nuclear fission reactors. Steam direct contact condensation (DCC) in sub-atmospheric conditions have never been implemented before, therefore an experimental assessment of the VVPSS is necessary to simulate this phenomenon in ITER's thermal-hydraulic conditions.Under the financial support of ITER Organization, an experimental program was performed at the Department of Civil and Industrial Engineering (DICI) of the University of Pisa in the past 3 years, using a small-scale experimental rig (1/22 scale factor).In order to assess the scale laws elaborated by means of the experimental results obtained in this small scale facility, a Large Scale facility was built at University of Pisa. This facility is almost a full scale mock-up of ITER's VVPSS from the geometric point of view (1/1.09 scale factor) and it is 1/10 scale factor from the steam mass flow rate point of view.This paper illustrates the results of the first test campaign. A 1/10 scale sparger system SPS-A (having a diameter equal to DN125 and 100 holes) was used with a maximum steam mass flow rate of 0.5 kg/s. This experimental configuration represents real operating conditions on the basis of the results of elaborated similitude analysis. The preliminary analysis of the experimental results confirms the agreement in terms of condensation regimes between the two reduced scale (1/22 and 1/10 scale) as foreseen by the elaborated scale laws.