To assess the antimicrobial effects, surface roughness (Ra), and color change (ΔE) of Morinda Citrofolia, Sapindus Mukorossi, Indocyanine green photosensitizer, and 2% NaOCl on metal ceramic crown colonized with C. Albicans, S aureus, S. mutans, and E. coli. An aggregate of 40 (n=10 each) Ni/Cr metal-ceramic crowns were fabricated and inoculated with the American Type Culture Collection (ATCC) of varied microbial colonies colonized by C. Albicans, S aureus, S. mutans, and E. coli. After inoculation, specimens were exposed to four different types of disinfection methods i.e. group 1: MC, group 2: SM, group 3:ICGP, and group 4 2% NaOCl respectively to evaluate antimicrobial efficacy, Ra, and color change. Later, the microbial assay was performed and expressed as CFU/ml (log 10). Ra was assessed using a surface analyzer and color change ΔE was evaluated using a spectrophotometer Statistical analysis was performed by using two-way ANOVA and Post HocTukey's test maintaining a significance level of p less than0.05. The highest antimicrobial efficacy for metallic-ceramic crown decontamination against all inspected microbial colonies was unveiled by group 1: MC, whereas the lowest disinfection efficacy was revealed by group 4 sterilized with 2% NaOCl (control). Metallic ceramic crown decontamination with MC and SM substantiated equivalent antimicrobial efficacy in plummeting CFU/mL (log10) of C.Albicans, S aureus, S.mutans, and E. coli (p>0.05). However, ICGP as a crown disinfectant validated antimicrobial efficacy significantly less compared to MC and SM (p<0.05). Ra was assessed post-disinfection with no changes observed (p>0.05) among all groups. Similarly, ΔE was significantly higher in crowns disinfected with ICGP (p<0.05) CONCLUSION: Metallic ceramic crown decontamination using herbal disinfectants Morinda Citrofolia and Sapindus Mukorossi exhibited favorable antimicrobial efficacies against microbial colonies of C. albicans, S aureus, S.mutans, and E. coli with no changes in surface roughness and color.